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Bruker Announces Three New GHz NMR Systems Orders for Functional Structural Biology and Clinical Phenomics Research

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Bruker Corporation has received three new orders for its Ascend Evo 1.0 GHz NMR magnets, designed for structural biology and clinical research in single-story laboratories. These orders are from the RIKEN Center for Biosystems Dynamics Research in Japan, and research centers in Spain. The Ascend Evo 1.0 GHz offers enhanced sensitivity, reduced helium consumption by 65%, and a smaller footprint, making advanced research accessible. Additionally, Bruker introduced the Heliosmart Recovery system for efficient helium recovery.

Positive
  • Three new orders for Ascend Evo 1.0 GHz NMR magnets enhance Bruker's market position.
  • Ascend Evo 1.0 GHz reduces helium consumption by 65%, lowering operational costs.
  • The compact design allows for installation in single-story labs, expanding accessibility for research.
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  • None.

Three Labs in Japan and Spain to Receive Novel Compact Ascend Evo 1.0 GHz Magnets

UTRECHT, The Netherlands--(BUSINESS WIRE)-- At the Euromar 2022 Conference, Bruker announced three new customer orders for GHz systems, which will incorporate novel, compact 1.0 GHz NMR magnets for structural biology applications and clinical research in single-story laboratories. The new Ascend Evo 1.0 GHz NMR magnet, operating at 4.2 Kelvin, allows functional structural biology and clinical phenomics researchers to dive deeper into the structural details, binding and dynamics of molecular structures and complexes for fundamental cell biology and pathobiology research. It complements Bruker’s Avance Neo 1.1 GHz and 1.2 GHz NMR systems with two-story 2 Kelvin magnets, which typically are used at shared national NMR facilities, such as the 1.2 GHz NMR at the Dutch Ultra-high Field Magnetic Resonance Consortium, operating at Utrecht University.

Compact 1.0 GHz NMR magnet Ascend Evo for structural biology applications and clinical research in single-story laboratories (Graphic: Business Wire)

Compact 1.0 GHz NMR magnet Ascend Evo for structural biology applications and clinical research in single-story laboratories (Graphic: Business Wire)

A first new 1.0 GHz NMR order comes from the RIKEN Center for Biosystems Dynamics Research in Yokohama, Japan. The RIKEN team under Dr. Ichio Shimada will use GHz NMR to study dynamical structures of biomolecules in solution and to investigate the relationships between dynamical structures and biological function or pathobiology.

Bruker also confirms two 1.0 GHz NMR orders from major research centers and universities in Bilbao and Barcelona, both in Spain, for clinical and biological research:

Professor Óscar Millet, Principal Investigator of the Precision Medicine and Metabolism Lab at CIC bioGUNE stated: “The Ascend Evo 1.0 GHz will advance our research in clinical metabolomics. This novel magnet provides highest-resolution NMR to investigate the molecular patterns and mechanism of action of prevalent and rare diseases in precision medicine, all in a single-story lab and with a smaller footprint.”

Professor Miquel Pons Valles, Group Leader of the BioNMR Group at Universitat de Barcelona and his team use biophysical methods, especially NMR, as well as chemical biology, molecular biology, and computations to study proteins in regulatory processes, where dynamics is essential for function. The Ascend Evo 1.0 GHz will also advance their research on intrinsically disordered proteins (IDPs).

The recently introduced, compact Ascend Evo 1.0 GHz NMR magnet has significantly reduced footprint, weight, and ceiling height requirements to fit into most single-story laboratories. Along with a 65% reduction in helium consumption, this provides more structural biology principal investigators, individual universities and research centers, as well as advanced biopharma companies access to the sensitivity and resolution of GHz NMR in order to enable new research capabilities.

Another innovation is Bruker’s new Heliosmart Recovery, a compact and easy-to-site system that collects helium boil-off from NMR magnets. Helium gas is stored in high-pressure cylinders, which can be used by cryogen suppliers for reliquification. The Heliosmart Recovery system can collect the steady-state boil-off of several NMR magnets in parallel with typical recovery rates of 80%85%.

Dr. Falko Busse, President of the Bruker BioSpin Group, commented: "We are excited to announce the three new GHz orders, which will incorporate our innovative, single-story Ascend Evo 1.0 GHz magnet. This technological marvel brings the power of GHz NMR to more laboratories due to its smaller footprint, reduced maintenance requirements and lower Helium consumption.”

Please join Bruker at Euromar at our booth for interaction with our NMR and EPR teams.

About Bruker Corporation (Nasdaq: BRKR)

Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular and cell biology research, in applied and pharma applications, in microscopy and nanoanalysis, as well as in industrial applications. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics. For more information, please visit: www.bruker.com.

Investors:

Justin Ward

Sr. Director, Investor Relations & Corporate Development

Bruker Corporation

T: +1 (978) 663-3660 x1479

E: Investor.Relations@bruker.com

Media:

Thorsten Thiel, Ph.D.

VP of Group Marketing

Bruker BioSpin

T: +49 7243 769 5500

E: pr@bruker.com

Source: Bruker Corporation

FAQ

What recent orders has Bruker Corporation received for its NMR systems?

Bruker received three orders for its Ascend Evo 1.0 GHz NMR magnets from Japan and Spain.

How does the <b>Ascend Evo 1.0 GHz</b> NMR magnet benefit researchers?

The Ascend Evo 1.0 GHz offers enhanced sensitivity, a smaller footprint, and 65% reduced helium consumption.

What is the significance of the <b>Heliosmart Recovery</b> system?

The Heliosmart Recovery system collects helium boil-off, achieving recovery rates of 80% – 85%, improving helium usage efficiency.

Who are the key customers for the new <b>Ascend Evo 1.0 GHz</b> systems?

Key customers include the RIKEN Center for Biosystems Dynamics Research in Japan and CIC bioGUNE and Universitat de Barcelona in Spain.

When was the announcement regarding new NMR systems made?

The announcement was made during the Euromar 2022 Conference.

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