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Biognosys and Alamar Biosciences Forge Strategic Partnership in Proteomics to Advance Biopharma and Precision Medicine Research

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Biognosys and Alamar Biosciences announce a strategic partnership to advance scientific discovery in biofluid proteomics biomarkers. The collaboration combines Biognosys' DIA-MS platform with Alamar's NULISA assays for deep proteomics insights. The partnership will be showcased at the AACR 2024 Annual Meeting with a focus on Non-Small Cell Lung Cancer.
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The strategic partnership between Biognosys and Alamar Biosciences signifies a notable advancement in the field of biofluid proteomics. The integration of Biognosys' DIA-MS platform with Alamar's NULISA assays could lead to significant improvements in the detection and quantification of low-abundance proteins, such as cytokines and chemokines, which are critical in understanding disease mechanisms and developing targeted therapies.

From an industry perspective, this collaboration is poised to enhance the capabilities of proteomics in clinical research. The potential to identify new biomarkers for diseases like Non-Small Cell Lung Cancer (NSCLC) could translate into better diagnostic tools and more personalized treatment options, which in turn may drive growth for both companies in the precision medicine market. The success of the proof-of-concept study in integrating data from both platforms suggests that this partnership could lead to commercially viable products and services, which would be of interest to investors monitoring the biotechnology sector.

The use of Biognosys' DIA-MS and Alamar's NULISA assays represents a dual approach to unraveling the complexities of the plasma proteome. The ability to cover the full dynamic range of protein abundance in plasma is a significant step forward in biomarker discovery and disease research. This could facilitate a deeper understanding of the pathophysiology of various conditions, potentially leading to breakthroughs in early disease detection and treatment.

For stakeholders, the implications of this partnership extend beyond the immediate commercial and scientific collaboration. The long-term benefits could include the acceleration of therapeutic development and a shift towards more predictive and preventative healthcare models. However, the scalability and cost-effectiveness of these technologies in clinical settings will be critical factors determining their adoption and impact on the market.

The announcement of the partnership between Biognosys and Alamar Biosciences may have a positive impact on investor sentiment, particularly as it highlights a successful proof-of-concept study and plans for further commercial and scientific collaboration. The focus on NSCLC, a disease with significant unmet medical needs, could position the companies favorably in a high-value segment of the healthcare market.

Investors should monitor the progression of this partnership closely, as the integration of these technologies into marketable products and services has the potential to capture a sizable share of the proteomics market. It is also worth noting that collaborations like this can often lead to increased interest from larger pharmaceutical companies, possibly resulting in acquisition opportunities or additional partnerships that can further enhance shareholder value.

  • Strategic partnership expands Biognosys' services to include Alamar's NULISA assays as well as joint scientific research in biofluid-based proteomics
  • Complementary value of Biognosys' DIA-MS unbiased proteomics platform and Alamar's game-changing immunoassay platforms to be presented at the AACR 2024 Annual Meeting

ZURICH and FREMONT, Calif. , April 4, 2024 /PRNewswire/ -- Biognosys, a global leader in mass spectrometry-based proteomics, and Alamar Biosciences, Inc., a company powering precision proteomics to enable the earliest detection of disease, are pleased to announce a strategic partnership aimed at advancing scientific discovery in the field of biofluid proteomics biomarkers. This collaboration brings together Biognosys' expertise in unbiased discovery through data independent acquisition mass spectrometry (DIA-MS) and Alamar's cutting-edge immunoassays. This integrated approach enhances our understanding of biomarkers by combining deep unbiased DIA-MS discovery proteomics with highly specific and ultra-sensitive mid- and high-plex NULISA assays for low-abundance proteins such as cytokines, chemokines and important disease protein biomarkers from plasma.

In the Industry Spotlight Theater session hosted by Alamar at the American Society for Cancer Research (AACR) 2024 Annual Meeting in San Diego on April 9 at 12:30 pm PT, the companies will jointly present data from a collaborative study focused on Non-Small Cell Lung Cancer (NSCLC). In this study, plasma samples from a cohort of NSCLC patients were analyzed using both the Biognosys TrueDiscovery® unbiased discovery platform and Alamar's NULISAseq™ Inflammation Panel 250. The findings demonstrate the feasibility of integrated analysis and highlight the complementary insights derived from mass spectrometry and affinity-based assays in plasma.

Building upon this successful proof-of-concept study, Biognosys and Alamar are planning to further collaborate both commercially and scientifically as part of their strategic partnership.

  1. NULISA Assay Services: Biognosys will offer NULISA assays from its state-of-the-art facility in Switzerland for previously hard to measure cytokines, chemokines, as well as other important disease specific markers from plasma and biofluids. These ultra-high sensitivity assays enable precise quantification of low abundance proteins, providing researchers with valuable insights into complex biological processes. They complement unbiased DIA-MS analysis of thousands of plasma proteins to elucidate systemic host response, and other inflammation or disease-related protein-fold changes.

  2. Research Collaboration: Biognosys and Alamar will embark on a joint research initiative to explore plasma biology. By leveraging Biognosys' unbiased discovery methods alongside Alamar's ultra-high sensitivity assays, the teams seek to unravel biological disease mechanisms by providing a more complete picture of the plasma proteome, enabling for the first time the coverage of essentially the complete dynamic range of protein abundance in plasma.

Oliver Rinner, Ph.D., Founder and CEO of Biognosys, expressed enthusiasm about the collaboration: "We are excited to join forces with Alamar to advance proteomics research. Our combined efforts will pave the way for breakthroughs in plasma biology by analyzing in an unbiased way more than 5,000 proteins together with panels of hundreds of well characterized cytokines and other high value low abundance proteins using highly specific NULISA assays. With this approach we are aiming to cover the whole dynamic range of plasma proteins."

"We are thrilled to partner with Biognosys to provide the research community with expanded access to proteomic insights from discovery through to clinical research," said Yuling Luo, Ph.D., Chairman, Founder and CEO of Alamar. "Biognosys is a leading provider of advanced mass spec proteomics services to researchers around the world, and we look forward to adding the highest sensitivity high-multiplex immunoassays to their plasma proteomics offering."

This partnership underscores the commitment of both companies to scientific excellence and their shared vision of advancing precision medicine through innovative technologies.

About Biognosys
At Biognosys, we believe that deep proteome insights hold the key to breakthrough discoveries that transform science for better lives. With our versatile portfolio of next-generation proteomics solutions, including the TrueDiscovery®, TrueTarget®, and TrueSignature® research service platforms, our flagship software Spectronaut®, and the PQ500™ kit, we make the proteome actionable to empower research, drug development, and clinical decision-making. Our solutions provide a multi-dimensional view of protein expression, function, and structure in all biological species and sample types. Our unique, patented technologies utilize high-resolution mass spectrometry to quantify thousands of proteins with industry-leading precision, depth, and throughput. Through our strategic partnership with Bruker (Nasdaq: BRKR), we make proteomics globally accessible. For more information, visit biognosys.com.

About Alamar
Alamar Biosciences is a privately held life sciences company with a mission to power precision proteomics to enable the earliest detection of disease. The company's proprietary NULISA Platform along with the ARGO™ HT System work seamlessly with the latest advances in genomics to achieve single digit attomolar detection sensitivity, greatly surpassing the most sensitive protein detection technology on the market today. For more information, please visit alamarbio.com.

Investor contact:
investors@alamarbio.com

Biognosys’ DIA mass spectrometry unbiased proteomics platform

Biognosys’ DIA proteomics analysis software, Spectronaut®

(PRNewsfoto/Alamar Biosciences, Inc.)

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SOURCE Alamar Biosciences, Inc.

FAQ

What is the strategic partnership announced between Biognosys and Alamar Biosciences?

The strategic partnership aims to advance scientific discovery in biofluid proteomics biomarkers by combining Biognosys' DIA-MS platform with Alamar's NULISA assays.

Where will the joint scientific research be presented?

The joint scientific research will be presented at the AACR 2024 Annual Meeting in San Diego.

What is the focus of the collaborative study presented at the AACR 2024 Annual Meeting?

The focus of the study is on Non-Small Cell Lung Cancer (NSCLC) using plasma samples from NSCLC patients.

What services will Biognosys offer as part of the partnership?

Biognosys will offer NULISA assays for cytokines, chemokines, and disease-specific markers from plasma and biofluids.

What is the goal of the joint research initiative between Biognosys and Alamar?

The goal is to explore plasma biology by combining unbiased discovery methods with ultra-high sensitivity assays to unravel biological disease mechanisms.

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