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Biotech Acquisition Company (Nasdaq: BIOT) announced it will not extend the time period for completing an initial business combination due to an investor's failure to deposit required funds. Consequently, the Company will dissolve and liquidate, redeeming its Public Shares at approximately $10.15 per share. This decision follows an extraordinary general meeting held on January 19, 2023. The liquidation process will involve instructing the Trust Account trustee to liquidate securities, with funds held in a non-interest bearing account until disbursement. The redemption is expected to complete within ten days after January 27, 2023.
Blade Therapeutics, a clinical-stage biopharmaceutical company, announced that Dr. Wendye Robbins will participate in the panel discussion "Drug Development in Pulmonary Medicine" on August 9, 2022, at the BTIG Biotechnology Conference in New York City. The company focuses on developing treatments for fibrotic and neurodegenerative diseases, with its lead drug, cudetaxestat, expected to enter phase 2 trials for idiopathic pulmonary fibrosis. Blade Therapeutics is positioned to deliver innovative therapies targeting key biological pathways integral to fibrosis and neurodegeneration.
Blade Therapeutics announced promising preclinical results for cudetaxestat, an investigational drug aimed at treating idiopathic pulmonary fibrosis (IPF). The findings reveal cudetaxestat's direct anti-fibrotic effects in a lung fibrosis model and its ability to inhibit autotaxin non-competitively, maintaining potency in fibrotic conditions. The company is set to initiate a phase 2 clinical trial in Q2 2022, showcasing its commitment to advancing treatments for fibrotic diseases. Additionally, the drug has received orphan drug designation, emphasizing its potential significance in this therapeutic area.
Blade Therapeutics announced positive results from phase 1 studies of cudetaxestat, an investigational treatment for idiopathic pulmonary fibrosis (IPF). No significant drug-drug interactions were found with the approved therapies pirfenidone and nintedanib, and cudetaxestat was well tolerated with no serious adverse events reported. The company plans to initiate a phase 2 clinical trial in Q2 2022, assessing cudetaxestat as a monotherapy and in combination with existing IPF treatments. This research highlights the potential of cudetaxestat to enhance current therapies for IPF.
Blade Therapeutics has received FDA feedback to advance its investigational drug, cudetaxestat, into a 26-week phase 2 clinical trial targeting patients with idiopathic pulmonary fibrosis (IPF). The trial is set to launch in Q2 2022, pending preclinical toxicology studies. This study will assess the safety and efficacy of cudetaxestat administered alone or with approved therapies. With orphan drug designation, cudetaxestat aims to address unmet needs in fibrotic disease treatment. Blade's merger with Biotech Acquisition Company is also progressing, potentially enhancing their market capabilities.
Blade Therapeutics will present three posters featuring data on cudetaxestat, an investigational drug for idiopathic pulmonary fibrosis (IPF), at the American Thoracic Society (ATS) 2022 International Conference from May 13-18, 2022. The presentations include findings from a phase 1 clinical study of cudetaxestat's interaction with approved IPF medications, including pirfenidone and nintedanib. The data aims to enhance understanding of safety, tolerability, and drug-drug interactions, which are critical for advancing treatment options for IPF and other fibrotic diseases.
On March 16, 2022, Biotech Acquisition Company (NASDAQ: BIOT) announced the public filing of a registration statement on Form S-4 with the SEC regarding its proposed merger with Blade Therapeutics, Inc. A definitive merger agreement was previously announced on November 8, 2021. The combined entity will be named Blade Biotherapeutics, Inc., and listed on Nasdaq as 'BBTX.' The transaction is supported by notable institutional investors, including Deerfield Management and Pfizer Ventures, with an initial IPO raising $230 million.
Blade Therapeutics, a biopharmaceutical company specializing in treatments for fibrotic and neurodegenerative diseases, announced that CEO Wendye Robbins will present at two investor conferences in March 2022. The events include Oppenheimer’s 32nd Annual Healthcare Conference on March 15 at 8:40 a.m. ET (virtual) and the Barclays Global Healthcare Conference on March 16 at 3:50 p.m. ET in Miami. Live and archived presentations can be accessed via Blade's website. Additionally, Biotech Acquisition Company (NASDAQ: BIOT) is set to merge with Blade, leading to the rebranding as Blade Biotherapeutics, Inc.
Blade Therapeutics announced positive results from a phase 1 clinical study of cudetaxestat, a non-competitive autotaxin inhibitor. The study showed that cudetaxestat was well tolerated with no serious adverse events reported during co-administration with approved IPF therapies, pirfenidone and nintedanib. Blade plans to submit data to the FDA in Q1 2022 and advance to a phase 2 study for idiopathic pulmonary fibrosis (IPF) in Q2 2022. Cudetaxestat has received orphan drug designations for IPF and systemic sclerosis, indicating a promising treatment avenue.
Blade Therapeutics has reported positive topline data from a Phase 1 clinical study of cudetaxestat, a non-competitive autotaxin inhibitor, indicating a favorable safety profile and no significant drug-drug interactions with CYP450 substrates. The study supports the initiation of a Phase 2 trial in idiopathic pulmonary fibrosis (IPF) planned for H1 2022. The drug received orphan designation from the FDA for systemic sclerosis. Blade’s focus on innovative therapies for fibrotic conditions highlights its potential in a critical market segment.
