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Bicycle Therapeutics to Participate at the 11th Annual SVB Leerink Global Healthcare Conference

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Bicycle Therapeutics plc (NASDAQ: BCYC), a pioneering biopharmaceutical company, announced participation in a fireside chat at the 11th Annual SVB Leerink Global Healthcare Conference on February 16, 2022, at 9:20 a.m. ET. The virtual event will be accessible on Bicycle's website, with an archived playback available for 90 days post-event. The company specializes in developing innovative therapeutics called Bicycles, which are being evaluated in multiple Phase I/II trials, targeting various cancer-related antigens.

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CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)-- Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today announced that management will participate in a fireside chat at the 11th Annual SVB Leerink Global Healthcare Conference on February 16, 2022 at 9:20 a.m. ET. The conference will be held in a virtual meeting format.

A live webcast of the fireside chat will be accessible in the Investors and Media section of Bicycle’s Website at www.bicycletherapeutics.com. An archived replay of the webcast will be available for 90 days following the fireside chat date.

About Bicycle Therapeutics

Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycles, for diseases that are underserved by existing therapeutics. Bicycles are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycles attractive candidates for drug development. Bicycle is evaluating BT5528, a second-generation Bicycle Toxin Conjugate (BTC™) targeting EphA2; BT8009, a second-generation BTC targeting Nectin-4, a well-validated tumor antigen; and BT7480, a Bicycle TICATM targeting Nectin-4 and agonizing CD137, in company-sponsored Phase I/II trials. In addition, BT1718, a BTC that targets MT1-MMP, is being investigated in an ongoing Phase I/IIa clinical trial sponsored by the Cancer Research UK Centre for Drug Development. Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, MA. For more information, visit bicycletherapeutics.com.

Investors:

David Borah, CFA

VP, Capital Markets & Investor Relations

david.borah@bicycletx.com

617-203-8300

Media:

Consilium Strategic Communications

Sukaina Virji or Mary-Jane Elliott

bicycle@consilium-comms.com

Source: Bicycle Therapeutics plc

FAQ

When is Bicycle Therapeutics participating in the SVB Leerink Global Healthcare Conference?

Bicycle Therapeutics will participate in the conference on February 16, 2022, at 9:20 a.m. ET.

How can I access the live webcast of Bicycle Therapeutics' fireside chat?

The live webcast can be accessed on Bicycle Therapeutics' website in the Investors and Media section.

What innovative therapeutics does Bicycle Therapeutics develop?

Bicycle Therapeutics develops a new class of medicines known as Bicycles, aimed at treating diseases underserved by current therapeutics.

What are the ongoing clinical trials involving Bicycle Therapeutics?

Bicycle Therapeutics has several ongoing Phase I/II trials, including BT5528, BT8009, and BT7480, targeting various cancer antigens.

Is there a replay available for the Bicycle Therapeutics fireside chat?

Yes, an archived replay of the fireside chat will be available for 90 days following the event.

Bicycle Therapeutics plc American Depositary Shares

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