Briacell Therapeutics Corp. Common Shares - BCTX STOCK NEWS

BriaCell Therapeutics Corp. (BCTX, BCTXW) will present new data on its immunotherapy, Bria-IMT™, at the SITC 37th Annual Meeting from November 10-12, 2022, in Boston, MA. The presentation highlights clinical benefits observed in advanced breast cancer patients, showcasing extended survival and tumor reductions in those matching specific HLA types. The session aims to further optimize off-the-shelf personalized immunotherapies. The poster presentation will be available online afterwards, offering insights into BriaCell's innovative approaches to cancer treatment.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has secured an exclusive license from the University of Maryland, Baltimore County to develop Soluble CD80 (sCD80) for cancer treatment. This innovative biologic agent aims to reverse immune suppression in cancer patients and may enhance anti-tumor immunity. Supported by promising animal study data, BriaCell plans to explore sCD80 as a standalone treatment or in combination with existing immunotherapies. The licensing agreement includes royalty payments to UMBC upon commercialization.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has partnered with Waisman Biomanufacturing to manufacture Bria-Pros™, a personalized immunotherapy for advanced prostate cancer. This collaboration aims to ensure the production of clinical supplies under good manufacturing practices (GMP). Bria-Pros™ consists of multiple HLA-specific immunotherapy cell lines tailored to patients' HLA types. The Phase I/II clinical trial is anticipated to begin after completion of manufacturing and regulatory processes. With prostate cancer being a significant health concern, this innovative approach may provide new treatment options.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has entered a research collaboration with Harvard Medical School, led by Dr. Joan S. Brugge, to identify novel anti-cancer treatment targets. The focus will be on enhancing tumor cell response to chemotherapy and immunotherapies for lung, head and neck, cervical, and bladder cancers. Under the one-year agreement, BriaCell may negotiate licenses for any innovations developed. This partnership aims to address significant challenges in precision cancer treatments and aligns with BriaCell's strategy for developing effective cancer therapies.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) announced significant findings from a publication on its lead candidate, Bria-IMT™, for advanced breast cancer. The research, published in Recent Patents on Anti-Cancer Drug Discovery, demonstrated Bria-IMT™'s ability to rapidly destroy tumors in patients with matching HLA types, aligning with BriaCell's strategy for off-the-shelf personalized immunotherapy. Clinical data indicated tumor shrinkage and an overall survival exceeding 33 months in some patients, affirming the drug's efficacy and safety.

Creatv Bio announced the results of its LifeTracDx® blood test for predicting response in metastatic breast cancer (mBC) therapy, to be presented at the ASCO Annual Meeting from June 3-7, 2022, in Chicago, IL. The study highlights the test's ability to assess tumor responsiveness after one therapy cycle, regardless of the therapy type. Notably, the presentation will include collaborations with BriaCell Therapeutics (NASDAQ: BCTX) as part of ongoing clinical developments. This innovative approach may enhance treatment personalization for mBC patients and is part of ongoing research efforts.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has activated Hoag Memorial Hospital and re-engaged Sylvester Comprehensive Cancer Center to enhance patient enrollment in its Phase I/IIa clinical trial for Bria-IMT™ in combination with Incyte’s therapies. The addition of these sites aims to accelerate patient recruitment, as BriaCell prepares for discussions with the FDA regarding safety and efficacy data. This phase of the trial includes several active sites across the U.S., representing BriaCell's ongoing commitment to advancing immunotherapy for advanced breast cancer.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) announced that the FDA has granted Fast Track status to its lead immunotherapy candidate, Bria-IMT™, aimed at treating metastatic breast cancer. This designation allows for quicker communication with the FDA, potentially leading to earlier drug approval and patient access. BriaCell is currently enrolling patients in a Phase I/IIa clinical trial, combining Bria-IMT™ with Incyte's checkpoint inhibitor retifanlimab and immunomodulator epacadostat.

BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has developed Bria-OTS™, a novel off-the-shelf personalized immunotherapy for advanced breast cancer, discussed during the AACR Annual Meeting 2022. This innovative treatment aims to match patients' HLA types using a simple saliva test, enhancing the likelihood of clinical benefits. The Bria-OTS™ therapy utilizes genetically modified cell lines to cater to over 99% of the population, accelerating treatment without complex manufacturing processes. An open-label Phase I/IIa clinical trial is anticipated to evaluate its safety and efficacy.