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BriaCell Therapeutics Corp (NASDAQ: BCTX) is a pioneering biotechnology company headquartered in Los Angeles, specializing in the development of immunotherapy treatments for cancer management. The company’s innovative approach focuses on harnessing the body's immune system to target and eliminate cancer cells, providing new hope for patients battling this devastating disease.
Central to BriaCell's portfolio is the BriaVax vaccine, which has shown promising results in early-phase clinical trials. In two compelling FDA Phase I studies involving late-stage breast cancer patients, BriaVax demonstrated unique and unprecedented outcomes, showcasing its potential as a groundbreaking treatment. Building on these successes, BriaCell is aggressively advancing towards a Phase I/II clinical trial, aiming to expand its vaccine's application to a larger cohort of breast cancer patients.
In addition to BriaVax, the company is also developing Bria-IMT, currently in a Phase I/IIa clinical trial targeting metastatic breast cancer. Bria-IMT represents a targeted and safe approach to treating advanced-stage breast cancer, reinforcing BriaCell's commitment to innovative cancer therapies. Another significant development in their pipeline is the Bria-OTS ('off-the-shelf') personalized immunotherapy, designed to match the patient's HLA type, further customizing and enhancing the treatment's effectiveness.
While BriaCell's current focus remains on breast cancer, the company is exploring the potential of applying its vaccine technology to other cancer types, broadening its impact in the oncology field. With a strategic vision and robust pipeline, BriaCell is poised to make significant contributions to cancer treatment and patient care.
For more detailed updates and the latest news about BriaCell Therapeutics Corp, visit their website or contact them directly. The company remains committed to transparency and regularly shares progress on their groundbreaking research and clinical trials.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has announced the addition of Mayo Clinic in Jacksonville, Florida, as a clinical site for its Phase I/II study of Bria-IMT™ combined with Incyte's PD-1 inhibitor, retifanlimab, aimed at treating advanced breast cancer. The study is part of BriaCell's mission to leverage innovative immunotherapy approaches to improve patient outcomes. Dr. Giuseppe Del Priore, the Chief Medical Officer, expressed optimism about the collaboration and the potential for advancements in cancer treatment.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has announced that its lead product candidate, Bria-IMT™, will be featured in three poster presentations at the 2022 San Antonio Breast Cancer Symposium from December 6-10. The presentations aim to share clinical findings with healthcare professionals treating advanced breast cancer patients who are unresponsive to existing therapies. The posters will be displayed at the Henry B. Gonzalez Convention Center in San Antonio, Texas. Copies will be available online after the event.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has partnered with Caris Life Sciences to enhance its capabilities in patient identification for clinical trials. The collaboration aims to expedite enrollment in a Phase I/II trial focused on advanced metastatic breast cancer. Caris will utilize its extensive oncology network and molecular profiling technologies to assist BriaCell in targeting patients most likely to benefit from its immunotherapy treatments. This partnership is expected to leverage Caris' advanced biomarker technology to improve patient outcomes.
BriaCell Therapeutics Corp. (BCTX, BCTXW) will present new data on its immunotherapy, Bria-IMT™, at the SITC 37th Annual Meeting from November 10-12, 2022, in Boston, MA. The presentation highlights clinical benefits observed in advanced breast cancer patients, showcasing extended survival and tumor reductions in those matching specific HLA types. The session aims to further optimize off-the-shelf personalized immunotherapies. The poster presentation will be available online afterwards, offering insights into BriaCell's innovative approaches to cancer treatment.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has secured an exclusive license from the University of Maryland, Baltimore County to develop Soluble CD80 (sCD80) for cancer treatment. This innovative biologic agent aims to reverse immune suppression in cancer patients and may enhance anti-tumor immunity. Supported by promising animal study data, BriaCell plans to explore sCD80 as a standalone treatment or in combination with existing immunotherapies. The licensing agreement includes royalty payments to UMBC upon commercialization.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has partnered with Waisman Biomanufacturing to manufacture Bria-Pros™, a personalized immunotherapy for advanced prostate cancer. This collaboration aims to ensure the production of clinical supplies under good manufacturing practices (GMP). Bria-Pros™ consists of multiple HLA-specific immunotherapy cell lines tailored to patients' HLA types. The Phase I/II clinical trial is anticipated to begin after completion of manufacturing and regulatory processes. With prostate cancer being a significant health concern, this innovative approach may provide new treatment options.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has entered a research collaboration with Harvard Medical School, led by Dr. Joan S. Brugge, to identify novel anti-cancer treatment targets. The focus will be on enhancing tumor cell response to chemotherapy and immunotherapies for lung, head and neck, cervical, and bladder cancers. Under the one-year agreement, BriaCell may negotiate licenses for any innovations developed. This partnership aims to address significant challenges in precision cancer treatments and aligns with BriaCell's strategy for developing effective cancer therapies.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) announced significant findings from a publication on its lead candidate, Bria-IMT™, for advanced breast cancer. The research, published in Recent Patents on Anti-Cancer Drug Discovery, demonstrated Bria-IMT™'s ability to rapidly destroy tumors in patients with matching HLA types, aligning with BriaCell's strategy for off-the-shelf personalized immunotherapy. Clinical data indicated tumor shrinkage and an overall survival exceeding 33 months in some patients, affirming the drug's efficacy and safety.
Creatv Bio announced the results of its LifeTracDx® blood test for predicting response in metastatic breast cancer (mBC) therapy, to be presented at the ASCO Annual Meeting from June 3-7, 2022, in Chicago, IL. The study highlights the test's ability to assess tumor responsiveness after one therapy cycle, regardless of the therapy type. Notably, the presentation will include collaborations with BriaCell Therapeutics (NASDAQ: BCTX) as part of ongoing clinical developments. This innovative approach may enhance treatment personalization for mBC patients and is part of ongoing research efforts.
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) has activated Hoag Memorial Hospital and re-engaged Sylvester Comprehensive Cancer Center to enhance patient enrollment in its Phase I/IIa clinical trial for Bria-IMT™ in combination with Incyte’s therapies. The addition of these sites aims to accelerate patient recruitment, as BriaCell prepares for discussions with the FDA regarding safety and efficacy data. This phase of the trial includes several active sites across the U.S., representing BriaCell's ongoing commitment to advancing immunotherapy for advanced breast cancer.
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