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Athira Pharma, Inc. - ATHA STOCK NEWS

Welcome to our dedicated page for Athira Pharma news (Ticker: ATHA), a resource for investors and traders seeking the latest updates and insights on Athira Pharma stock.

Athira Pharma, Inc. (NASDAQ: ATHA) is a late clinical-stage biopharmaceutical company based in the Seattle, Washington area, dedicated to developing small molecule therapeutics aimed at restoring neuronal health and slowing neurodegeneration. Athira's innovative pipeline includes several promising compounds, particularly targeting the neurotrophic hepatocyte growth factor (HGF) system, which plays a crucial role in nervous system maintenance and repair.

The company’s lead candidate, Fosgonimeton (ATH-1017), is a subcutaneously administered small molecule designed to positively modulate the HGF/MET system. It is currently being evaluated in the Phase 2/3 LIFT-AD clinical trial for the treatment of mild-to-moderate Alzheimer’s disease, with topline data expected in the second half of 2024. Fosgonimeton has shown potential in enhancing neuroprotective, neurotrophic, and anti-inflammatory pathways, which are critical in combating neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.

In addition to Fosgonimeton, Athira’s pipeline includes ATH-1105 and ATH-1020, both designed to be orally available treatments enhancing the HGF/MET system. ATH-1105 is particularly promising in preclinical models of amyotrophic lateral sclerosis (ALS), demonstrating significant neuroprotective effects, enhanced survival, and improved motor and nerve functions. The company plans to initiate first-in-human studies for ATH-1105 in the first half of 2024.

Athira's research is bolstered by funding from notable organizations such as the Alzheimer’s Drug Discovery Foundation, Washington’s Life Sciences Discovery Fund, and Dolby Family Ventures. This support underscores the company’s strong financial position and its capacity to advance its therapeutic candidates through key development milestones.

Recent updates highlight the therapeutic potential of Athira’s small molecules. For instance, fosgonimeton has demonstrated promising results in preclinical models of Alzheimer’s and Parkinson’s diseases, showing neuroprotective effects and improvement in cognitive and motor functions. Additionally, ATH-1105's preclinical studies have shown consistent beneficial effects in ALS models, reinforcing Athira’s approach and commitment to developing novel therapies for neurodegenerative diseases.

Athira is also active in the scientific community, regularly presenting its findings at major conferences and publishing in peer-reviewed journals. The company’s efforts are focused on leveraging its patented technologies to develop cost-effective treatments that address the root causes of neurodegenerative diseases, setting it apart from competitors that primarily target disease symptoms.

For more information about Athira Pharma, Inc., visit www.athira.com and follow the company on Facebook, LinkedIn, X (formerly known as Twitter), and Instagram.

Rhea-AI Summary

Athira Pharma (NASDAQ: ATHA) recently showcased preclinical data at the AD/PD 2023 conference, indicating that fosgonimeton may provide significant neuroprotective, neurotrophic, and anti-inflammatory benefits. Highlights include protection against neurite degeneration and cell death in neuronal cultures, reduced hyperphosphorylated tau levels, and decreased α-synuclein aggregation. The data suggests fosgonimeton could play a role in addressing Alzheimer’s and Parkinson’s diseases. Athira focuses on developing small molecules to restore neuronal health and progress its pipeline targeting the HGF/MET neurotrophic system.

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Athira Pharma, Inc. (NASDAQ: ATHA) reported its financial results for the year ending December 31, 2022. The company is advancing its Phase 2/3 LIFT-AD trial of fosgonimeton for mild-to-moderate Alzheimer’s disease, aiming for enrollment completion by mid-2023 and topline data in early 2024. Athira also progresses with ATH-1105 for ALS and maintains a robust balance sheet with $245.2 million in cash, down from $319.7 million in 2021. The net loss for 2022 was $95.6 million, or $2.53 per share, compared to a loss of $54.9 million, or $1.49 per share, in 2021. Increased operational costs were noted in R&D and G&A expenses.

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Athira Pharma (NASDAQ: ATHA) is set to showcase its innovative small molecule therapeutics aimed at enhancing the HGF/MET system for treating various neurodegenerative diseases.

On March 15, 2023, Athira's management will participate in the Needham Neurosciences Investor Forum, followed by the Stifel 2023 CNS Days on March 28-29, 2023. Investors can access live webcasts of the presentations on Athira's website.

Focused on restoring neuronal health, Athira is advancing treatments for Alzheimer's and Parkinson's diseases, among others. The company emphasizes its commitment to developing effective therapies.

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Rhea-AI Summary

Athira Pharma, a late clinical-stage biopharmaceutical company, will present at two scientific conferences: ASENT 2023 from March 13-15 and AD/PD 2023 from March 28-April 1. The presentations will showcase preclinical data on enhancing the HGF/MET pathway for neurodegenerative diseases. Key presentations include oral and poster sessions focused on ATH-1105, ATH-1020, and Fosgonimeton, highlighting their neuroprotective properties in models of ALS, diabetic neuropathic pain, Alzheimer's, and Parkinson's diseases. These engagements aim to demonstrate the therapeutic potential of Athira's product candidates, emphasizing their innovative approach to restoring neuronal health.

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Athira Pharma (NASDAQ: ATHA) recently released a review paper emphasizing the urgent need for innovative treatments for Alzheimer’s disease, specifically highlighting the potential of fosgonimeton, a small molecule modulator of the HGF/MET system. Published in the Journal of Alzheimer’s Disease, the article discusses current drug development limitations and the necessity for novel research methodologies. Athira's clinical candidate is currently being evaluated in the Phase 2/3 LIFT-AD study, targeting mild-to-moderate Alzheimer’s disease, with enrollment expected to conclude by mid-2023 and topline results anticipated in early 2024.

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Athira Pharma, Inc. (NASDAQ: ATHA) has promoted Kevin Church, Ph.D., to Chief Scientific Officer, recognizing his vital role in advancing the company’s research on neurodegenerative diseases. Dr. Church, who has been with Athira since 2016, previously served as Executive Vice President of Research and has been instrumental in exploring the HGF/MET pathway for potential therapies targeting Alzheimer's, Parkinson's, and other neurological disorders. His leadership is expected to strengthen the company’s innovative approach to restoring neuronal health.

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Athira Pharma (NASDAQ: ATHA) provided a pipeline update, highlighting its ongoing Phase 2/3 LIFT-AD study for mild-to-moderate Alzheimer’s disease with expected topline data in early 2024. The study aims to investigate the candidate fosgonimeton for neuroprotective effects. Additionally, ATH-1105, targeting amyotrophic lateral sclerosis (ALS), is set for an IND filing in 2023. Athira reported a solid financial position with $260 million in cash as of September 30, 2022, reinforcing its capability to advance its development programs.

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Athira Pharma (NASDAQ: ATHA) published preclinical data on December 20, 2022, highlighting the neuroprotective and cognitive-enhancing effects of fosgonimeton (ATH-1017). This research demonstrates fosgonimeton's potential in enhancing the HGF/MET neurotrophic system, crucial for addressing dementia and neurodegenerative diseases. The study shows that fosgonimeton promotes neuronal protection and cognitive improvement in various animal models affected by neurodegeneration. These findings support ongoing clinical development efforts targeting diseases like Alzheimer's and Parkinson's.

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Athira Pharma (NASDAQ: ATHA) presented findings on ATH-1105, a small molecule positive modulator of the HGF/MET neurotrophic system, at the 33rd International Symposium on ALS/MND. In a TDP-43 mouse model of ALS, ATH-1105 demonstrated significant improvements in motor function, nerve function, and reductions in neurodegeneration markers. Treated mice showed better weight retention, enhanced motor skills, and reduced inflammation biomarkers. These results support ATH-1105 as a potential therapeutic candidate for ALS and possibly other neurodegenerative diseases.

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Athira Pharma (NASDAQ: ATHA) announced a virtual R&D event titled “Enhancing the HGF/MET System to Fight Neurodegenerative Diseases,” scheduled for December 7, 2022, from 2:00 p.m. to 3:30 p.m. EST. The event will showcase preclinical and clinical data supporting the potential of HGF/MET in treating neurodegenerative diseases. Key executives, including Mark Litton, will present updates on Athira’s therapeutic pipeline, followed by an interactive Q&A session. Interested participants can pre-register and access the live webcast on Athira's website.

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FAQ

What is the current stock price of Athira Pharma (ATHA)?

The current stock price of Athira Pharma (ATHA) is $0.576 as of December 20, 2024.

What is the market cap of Athira Pharma (ATHA)?

The market cap of Athira Pharma (ATHA) is approximately 20.7M.

What is Athira Pharma, Inc.?

Athira Pharma, Inc. is a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and slow neurodegeneration.

What are Athira's lead compounds?

Athira's lead compounds include Fosgonimeton (ATH-1017) for Alzheimer's disease, ATH-1105 for ALS, and ATH-1020 for neurodegenerative disorders.

What is the focus of Athira's research?

Athira's research focuses on modulating the neurotrophic hepatocyte growth factor (HGF) system to treat neurodegenerative diseases.

When are the next significant milestones for Athira?

Athira expects to report topline data from its Phase 2/3 LIFT-AD trial for Fosgonimeton in Alzheimer’s disease in the second half of 2024 and to initiate first-in-human studies for ATH-1105 in 2024.

Who funds Athira's research?

Athira's research is funded by organizations such as the Alzheimer’s Drug Discovery Foundation, Washington’s Life Sciences Discovery Fund, and Dolby Family Ventures.

What differentiates Athira's approach from other companies?

Athira differentiates itself by targeting the neurodegenerative process and developing cost-effective solutions that address the root causes of neurodegenerative diseases.

What is Fosgonimeton?

Fosgonimeton (ATH-1017) is Athira's lead compound, designed to enhance the neurotrophic HGF system and currently being tested for Alzheimer's disease.

What recent achievements has Athira reported?

Recent achievements include promising preclinical results for ATH-1105 in ALS models and the completion of Phase 2/3 LIFT-AD trial enrollment for Fosgonimeton in Alzheimer’s disease.

How does Athira contribute to the scientific community?

Athira regularly presents its research at major scientific conferences and publishes in peer-reviewed journals, contributing to the broader understanding of neurodegenerative diseases.

Where can I find more information about Athira Pharma?

More information about Athira Pharma, Inc. can be found on their official website at www.athira.com and their social media pages on Facebook, LinkedIn, X (formerly Twitter), and Instagram.

Athira Pharma, Inc.

Nasdaq:ATHA

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ATHA Stock Data

20.71M
31.97M
1.95%
62.14%
4.05%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
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