Annovis Bio to Present at the New York Academy of Sciences’ Alzheimer's Disease Therapeutics: Alternatives to Amyloid 2020 Virtual Conference

Rhea-AI Summary

Annovis Bio (NYSE American: ANVS), a clinical-stage company focused on neurodegenerative diseases, announces that CEO Maria Maccecchini will present at the New York Academy of Sciences’ virtual conference on December 4, 2020. Her presentation will cover the company's lead candidate, ANVS401, which aims to lower neurotoxic proteins linked to Alzheimer’s and Parkinson’s diseases. Annovis is currently conducting two Phase 2a studies, expecting preliminary results in early 2021, showcasing its unique approach to neurodegeneration.

BERWYN, Pa., Dec. 03, 2020 (GLOBE NEWSWIRE) -- Annovis Bio Inc. (NYSE American: ANVS), a clinical-stage drug platform company addressing Alzheimer’s disease (AD), Parkinson’s disease (PD) and other neurodegenerative diseases, today announced its CEO, Maria Maccecchini, Ph.D., will present at the New York Academy of Sciences’ Alzheimer's Disease Therapeutics: Alternatives to Amyloid 2020 Virtual Conference on Friday, December 4, 2020.

Dr. Maccecchini’s presentation, “Targeting Increased Levels of Neurotoxic Proteins in Down Syndrome, Alzheimer’s and Parkinson’s Animals Normalized Axonal Transport, Cognition and Function,” will highlight the Company’s data that demonstrates by lowering amyloid, tau, and alpha-synuclein, the Company’s lead candidate, ANVS401, restores axonal transport and nerve cell health.

“Our approach to neurodegeneration is unique when compared to the long list of failed trials exclusively targeting amyloid,” stated Dr. Maccecchini. “I am excited to share our promising data with the conference attendees at this first major event of its type dedicated to non-amyloid approaches to AD.”

ANVS401 inhibits more than one neurotoxic protein and, thereby, improves axonal transport and reverses the toxic cascade leading to nerve cell death. The Company is presently in two ongoing double-blind, placebo-controlled Phase 2a studies that were designed to measure the toxic cascade that leads to nerve cell death and expects preliminary data in both AD and PD patients in the first half of 2021.

About Annovis Bio

Headquartered in Berwyn, Pennsylvania, Annovis Bio, Inc. (Annovis) is a clinical-stage, drug platform company addressing neurodegeneration, such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Alzheimer’s in Down Syndrome (AD-DS). We believe that we are the only company developing a drug for AD, PD and AD-DS that inhibits more than one neurotoxic protein and, thereby, improves the information highway of the nerve cell, known as axonal transport. When this information flow is impaired, the nerve cell gets sick and dies. We expect our treatment to improve memory loss and dementia associated with AD and AD-DS, as well as body and brain function in PD. We have an ongoing Phase 2a study in AD patients and have commenced a second Phase 2a study in AD and PD patients. For more information on Annovis, please visit the company’s website: www.annovisbio.com.

Forward-Looking Statements

Statements in this press release contain “forward-looking statements” that are subject to substantial risks and uncertainties. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “expect,” “believe,” “will,” “may,” “should,” “estimate,” “project,” “outlook,” “forecast” or other similar words, and include, without limitation, statements regarding the timing, effectiveness and anticipated results of ANVS401 clinical trials. Forward-looking statements are based on Annovis Bio, Inc.’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate, including that clinical trials may be delayed. These and other risks and uncertainties are described more fully in the section titled “Risk Factors” in the Annual Report on Form 10-K for the year ended December 31, 2019 filed with the Securities and Exchange Commission. Forward-looking statements contained in this announcement are made as of this date, and Annovis Bio, Inc. undertakes no duty to update such information except as required under applicable law.

Investor Relations:

Dave Gentry, CEO
RedChip Companies Inc.
407-491-4498
Dave@redchip.com

SOURCE: Annovis Bio, Inc.

FAQ

What is Annovis Bio's lead candidate, ANVS401?

ANVS401 is a drug aimed at lowering neurotoxic proteins associated with Alzheimer's and Parkinson's diseases, improving axonal transport and nerve cell health.

When will Annovis Bio present at the New York Academy of Sciences conference?

Annovis Bio's CEO will present at the conference on December 4, 2020.

What are the objectives of Annovis Bio's Phase 2a studies?

The Phase 2a studies aim to measure the toxic cascade leading to nerve cell death in Alzheimer's and Parkinson's patients.

What unique approach does Annovis Bio use for treating neurodegeneration?

Annovis Bio targets multiple neurotoxic proteins instead of solely focusing on amyloid, as seen in many failed trials.

When can we expect preliminary data from Annovis Bio's clinical trials?

Preliminary data from the Phase 2a studies is expected in the first half of 2021.