ANGLE PLC S/ADR - ANPCY STOCK NEWS

ANGLE plc announced its interim results for the six months ending June 30, 2022. Key highlights include FDA De Novo clearance for the Parsortix system, marking a significant advancement for cancer cell analysis. Revenue increased to £0.4 million, despite a loss of £9.2 million, attributed to planned investments. The company has established a partnership with Solaris Health for prostate cancer studies and showcased positive ovarian cancer results with a ROC-AUC of 95.4%. A fundraising initiative raised £20.1 million post-period end.

ANGLE plc has announced significant findings from a study conducted by the University of Birmingham on head and neck squamous cell carcinoma (HNSCC), showcasing the utility of circulating tumor cells (CTCs) in determining the epithelial-mesenchymal transition (EMT) status. The study revealed that 65% of treatment-naïve patients had detectable CTCs, with 77% undergoing EMT, correlating with advanced disease stages. The findings suggest that CTC EMT biomarkers may serve as complementary tools to traditional tumor biopsies, potentially improving patient outcomes in targeted therapy.

ANGLE plc presented a new poster at the 100th American Society for Clinical Pathology (ASCP) meeting, showcasing a novel application of the Pap stain technique to analyze circulating tumor cells (CTCs) harvested using the Parsortix system. This method, which could easily be integrated into standard pathology workflows, was recognized as a finalist for a prestigious Blue Ribbon award. The findings indicate that patient sample CTC analysis can be reliably conducted, aiding in clinical assessments of cancer patients, particularly those in remission.

ANGLE plc has announced the publication of results from a collaborative clinical study with the Wilmot Cancer Institute, demonstrating the effectiveness of the Parsortix system in predicting malignancy in pelvic masses. The MAGIC algorithm used in the study showed a high accuracy of 95.1% in identifying cancer, outperforming traditional serum biomarkers. This novel triage test aims to improve early detection of ovarian cancer, addressing a critical need as 20,000 ovarian cancer diagnoses occur annually in the US. ANGLE plans to establish this test in its clinical laboratories following ongoing verification studies.

ANGLE plc (OTCQX: ANPCY) will release its interim results for the six months ended June 30, 2022, on September 29, 2022. An analyst meeting is scheduled for 11:00 am BST at FTI Consulting’s London office and will be available via a live webcast. The Parsortix® system, which captures circulating tumor cells from blood, is FDA cleared for metastatic breast cancer, marking a significant achievement in liquid biopsy technology. ANGLE's technologies have shown promising results in clinical studies, enhancing diagnostic accuracy and potential in cancer treatment.

ANGLE plc (OTCQX:ANPCY) has announced the issuance of 33,332 new ordinary shares following the exercise of employee options. These shares will rank pari passu with existing shares and are expected to commence trading on AIM on July 13, 2022. Post-admission, the total number of ordinary shares will reach 235,328,048, thereby increasing total voting rights. ANGLE's Parsortix system, FDA cleared for use in metastatic breast cancer, continues to gain traction in the liquid biopsy market, underlining the company's commitment to cancer diagnostics and monitoring.

ANGLE plc (AIM:AGL)(OTCQX:ANPCY) announced that all resolutions were passed at their Annual General Meeting on June 29, 2022. The company specializes in liquid biopsy technology, particularly its Parsortix system, which has received FDA clearance for harvesting circulating tumor cells from blood in metastatic breast cancer patients. ANGLE is developing additional clinical applications, including a pelvic mass triage test showing 95.1% accuracy. Its technologies are supported by collaborations with major corporations and cancer centers to enhance clinical utility.

ANGLE plc has announced significant research results from ETH Zurich, revealing that breast cancer metastasis accelerates during sleep. The study found that circulating tumor cells (CTCs) and their clusters are more prevalent and aggressive at rest. This discovery suggests a potential for time-controlled cancer treatments that could optimize patient care. The findings underscore the role of circadian rhythms and associated hormones in cancer cell behavior, providing new avenues for drug development and improving treatment strategies for breast cancer.

ANGLE plc (OTCQX:ANPCY) has issued 144,999 new ordinary shares following the exercise of employee options. These shares will rank equally with existing shares. The admission for trading is expected to commence on June 28, 2022, increasing the total shares in issue to 235,294,716. This move reflects the company's ongoing efforts to support its liquid biopsy solutions, particularly the Parsortix system, which is FDA cleared for metastatic breast cancer. The press release highlights ANGLE's commitment to innovation and growth in cancer diagnostics.