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Angle PLC Announces Notice of Interim Results and Webcast

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ANGLE plc (OTCQX:ANPCY) will release its interim results for the six months ending June 30, 2021, on September 30, 2021. A virtual meeting for analysts starts at 10:00 AM BST the same day. Registration is required to attend the webcast, which serves as a watch-only platform with Q&A reserved for analysts. ANGLE is a leader in liquid biopsy, known for its Parsortix technology enabling non-invasive cancer cell analysis. The company aims for FDA clearance for CTC harvesting, which could elevate its market position significantly.

Positive
  • ANGLE aims for first-ever FDA clearance for CTC harvesting, enhancing market credibility.
  • Parsortix technology is patented and CE Mark approved, indicating a strong legal standing.
Negative
  • No significant financial metrics or results prior to interim results release, leading to uncertainty.

GUILDFORD, SURREY / ACCESSWIRE / September 7, 2021 / ANGLE plc (AIM:AGL)(OTCQX:ANPCY), a world-leading liquid biopsy company, will be releasing its interim results for the six months ended 30 June 2021 on Thursday 30 September 2021.

A virtual meeting and webcast for analysts will be held at 10:00 am BST on Thursday 30 September 2021. If you wish to attend, please register in advance and log on to the webcast approximately 5 minutes before 10.00 am on the day of the results. Details of how to attend can be accessed via ANGLE's Investor Centre page, https://angleplc.com/investor-relations. This link is to watch and listen only as Q&A time is reserved for analysts. A recording of the webcast will be made available on ANGLE's website following the results meeting.

For further information:

ANGLE plc

+44 (0) 1483 343434

Andrew Newland, Chief Executive
Ian Griffiths, Finance Director
Andrew Holder, Head of Investor Relations

finnCap Ltd (NOMAD and Joint Broker)
Corporate Finance - Carl Holmes, Simon Hicks, Teddy Whiley
ECM - Alice Lane, Sunila de Silva

+44 (0)20 7220 0500

WG Partners (Joint Broker)
Nigel Barnes, Nigel Birks

+44 (0) 203 705 9330

FTI Consulting
Simon Conway, Ciara Martin
Matthew Ventimiglia (US)


+44 (0) 203 727 1000
+1 (212) 850 5624

For Frequently Used Terms, please see the Company's website on https://angleplc.com/investor-relations/glossary/

Notes for editors

About ANGLE plc www.angleplc.com

ANGLE is a world leading liquid biopsy company with sample-to-answer solutions. ANGLE's proven patent protected platforms include a circulating tumor cell (CTC) harvesting technology and a downstream analysis system for cost effective, highly multiplexed analysis of nucleic acids and proteins.

ANGLE's cell separation technology is called the Parsortix® system, and it enables a liquid biopsy (a simple blood test) to be used to provide the cells of interest to the user in a format suitable for multiple types of downstream analyses. The system is based on a microfluidic device that captures cells based on a combination of their size and compressibility. The system is epitope independent and can capture all types of CTCs as well as CTC clusters in a viable form (alive). CTCs enable the complete picture of a cancer to be seen; as being an intact cell they allow DNA, RNA and protein analysis and may provide comparable analysis to a tissue biopsy. Because CTC analysis is a non-invasive process, unlike tissue biopsy, it can be repeated as often as needed. This is important because cancer develops and changes over time and there is a clear medical need for up-to-date information on the status of a patient's tumor. In addition, the live CTCs harvested by the Parsortix system can be cultured, which offers the potential for testing tumor response to drugs outside the patient.

The Parsortix technology is the subject of 26 granted patents in Europe, the United States, China, Australia, Canada, India, Japan and Mexico with three extensive families of patents are being progressed worldwide.

The Parsortix system has a CE Mark in Europe for the indicated use and, in the United States, a De Novo Submission has been made to FDA for the Parsortix® PC1 system seeking FDA clearance with Class II Classification for use with metastatic breast cancer patients. FDA clearance is seen as the global standard. ANGLE is seeking to be the first ever FDA cleared system for harvesting CTCs for subsequent analysis.

ANGLE has also completed two separate 200 subject clinical studies under a program designed to develop an ovarian cancer pelvic mass triage test, with the results showing best in class accuracy (AUC-ROC) of 95.1%. The pelvic mass triage assay has undergone further refinement and optimisation and a 200 patient clinical verification study has now completed enrolment.

ANGLE's technology for the multiplex evaluation of proteins and nucleic acids of all types is called the HyCEADTM platform and is based on a patented flow through array technology. It provides for low cost, highly multiplexed, rapid and sensitive capture of targets from a wide variety of sample types. A proprietary chemistry approach (the HyCEAD method) allows for the capture and amplification of over 100 biomarkers simultaneously in a single reaction. The HyCEAD system is extremely sensitive and is ideal for measuring gene expression and other markers directly from Parsortix harvests and was used in the ovarian cancer pelvic mass triage test to achieve best in class accuracy (AUC-ROC) of 95.1%.

ANGLE's proprietary technologies can be combined to provide automated, sample-to-answer results in both centralised laboratory and point-of-use cartridge formats.

ANGLE has established formal collaborations with world-class cancer centres and major corporates such as Abbott, Philips and QIAGEN, and works closely with leading CTC translational research customers. These Key Opinion Leaders (KOLs) are working to identify applications with medical utility (clear benefit to patients), and to secure clinical data that demonstrates that utility in patient studies. The body of evidence as to the benefits of the Parsortix system is growing rapidly from our own clinical studies in metastatic breast cancer and ovarian cancer and also from KOLs with 47 peer-reviewed publications and numerous publicly available posters, available on our website.

ANGLE has established clinical services laboratories in the UK and USA to accelerate commercialisation of the Parsortix system and act as demonstrators to support product development. The laboratories offer services to pharmaceutical and biotech customers for use of Parsortix in cancer drug trials and, once the laboratories are accredited and tests validated, will provide Laboratory Developed Tests (LDTs) for patient management.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: ANGLE plc



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FAQ

When will ANGLE plc release its interim results for 2021?

ANGLE plc will release its interim results on September 30, 2021.

What is the stock symbol for ANGLE plc?

ANGLE plc's stock symbol is ANPCY on the OTCQX.

What technology does ANGLE plc specialize in?

ANGLE plc specializes in liquid biopsy technology, particularly the Parsortix system.

What is the significance of the FDA clearance for ANGLE plc?

FDA clearance for CTC harvesting would be a significant milestone, positioning ANGLE as a leader in the market.

What time is the webcast for ANGLE plc’s interim results?

The webcast for ANGLE plc’s interim results is scheduled for 10:00 AM BST on September 30, 2021.

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