Welcome to our dedicated page for Altimmune news (Ticker: ALT), a resource for investors and traders seeking the latest updates and insights on Altimmune stock.
Altimmune Inc (ALT) is a clinical-stage biopharmaceutical company pioneering peptide-based therapeutics for obesity, metabolic disorders, and liver diseases. This page serves as the definitive source for verified news and press releases directly from the company and trusted financial publications.
Investors and researchers will find timely updates on clinical trial progress, including developments for pemvidutide, the company’s GLP-1/glucagon dual receptor agonist candidate. Track regulatory milestones, partnership announcements, and strategic initiatives that shape Altimmune’s research pipeline.
Our curated news feed includes earnings reports, scientific presentations, and manufacturing updates, providing a holistic view of the company’s trajectory. All content is rigorously vetted to ensure alignment with financial reporting standards and clinical accuracy.
Bookmark this page for efficient access to Altimmune’s latest material events. Check regularly for updates on pivotal studies in metabolic-associated steatohepatitis (MASH) and obesity therapeutics, ensuring you stay informed on developments impacting this innovative biopharma leader.
Altimmune (ALT) announced key developments in Q3 2024, including completion of enrollment in the Phase 2b IMPACT trial of pemvidutide for MASH, with top-line data expected in Q2 2025. The company successfully completed its End-of-Phase 2 FDA meeting for pemvidutide's obesity program, planning four Phase 3 trials. At EASD, they presented promising data showing pemvidutide's lean mass preservation and visceral fat reduction. The company plans to submit INDs for up to three additional pemvidutide indications starting Q4 2024.
Financial results showed $139.4 million in cash and investments, R&D expenses of $19.8 million, and a net loss of $22.8 million ($0.32 per share) for Q3 2024.
Altimmune (Nasdaq: ALT) has appointed Greg Weaver as Chief Financial Officer, effective immediately. Weaver brings over 25 years of finance experience in life sciences companies and will lead the company's finance, accounting, and investor relations functions. His previous role was CFO at Cognito Therapeutics, and he notably led a $225 million IPO at atai Life Sciences. Throughout his career, Weaver has managed various capital market transactions and served as CFO at multiple biotech companies, including Sirna Therapeutics and ILEX Oncology. The appointment comes at a important time as Altimmune advances its lead program, pemvidutide, which targets metabolic disorders through liver-targeting mechanisms.
Altimmune (Nasdaq: ALT) announced equity awards granted to incoming Chief Financial Officer Gregory Weaver, effective November 11, 2024. The compensation package includes options to purchase 225,000 shares of common stock and 75,000 restricted stock units (RSUs). Based on November 8 closing price, approximately 172,920 options would be issued as inducement awards, with the remainder as incentive stock options. The options and RSUs will vest over four years, with 25% vesting after the first year and the remainder vesting gradually, subject to continued employment.
Altimmune (Nasdaq: ALT) announced successful completion of End-of-Phase 2 Meeting with FDA for pemvidutide in obesity treatment. The company received agreement on Phase 3 registrational program design, which will include four Phase 3 trials (VELOCITY-1,2,3,4) enrolling approximately 5,000 subjects over 60-week periods. The trials will evaluate pemvidutide doses of 1.2 mg, 1.8 mg, and 2.4 mg, focusing on different patient populations including those with elevated LDL cholesterol, elevated liver fat, and elderly with sarcopenia. The program aims to leverage pemvidutide's balanced GLP-1/glucagon dual agonism benefits.
Altimmune (Nasdaq: ALT) has announced its participation in two upcoming investor conferences. The company will attend the Guggenheim Inaugural Healthcare Innovation Conference in Boston on November 11, 2024, featuring a fireside chat at 11:30 a.m. Eastern Time. Additionally, they will participate in the UBS Global Healthcare Conference in Rancho Palos Verdes on November 13, 2024, with a fireside chat scheduled for 9:30 a.m. Pacific Time and availability for one-on-one meetings. Both sessions will be accessible via webcast through the Events section of Altimmune's website.
Altimmune (Nasdaq: ALT) announced it will release its third quarter 2024 financial results on Tuesday, November 12, 2024. The clinical-stage biopharmaceutical company will host a conference call at 8:30 am E.T. on the same day to discuss the financial results and provide a business update. The conference call will be webcast live on Altimmune's Investor Relations website, with a replay available for up to three months after the call.
Altimmune (Nasdaq: ALT) announced new data on the lipidomic profile of subjects treated with pemvidutide will be presented at The Liver Meeting® 2024 of the American Association for the Study of Liver Diseases (AASLD) in San Diego, CA, November 15-19, 2024. The data shows reductions in multiple classes of atherogenic and cardio-inflammatory lipids from a 12-week Phase 1b randomized, placebo-controlled study in subjects with metabolic dysfunction-associated steatotic liver disease (MASLD).
The presentation, titled "Effect of Pemvidutide, a GLP-1/Glucagon Dual Receptor Agonist, on Plasma Lipidomic Profiles in Subjects with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)," will be given by Dr. Sarah K. Browne on Friday, November 15, 2024, at 1:00 pm PST. Altimmune has also completed enrollment in a Phase 2b efficacy trial of pemvidutide in patients with biopsy-confirmed F2/F3 MASH, with topline data expected in Q2 2025.
Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, has announced its participation in the H.C. Wainwright 8th Annual MASH Virtual Conference. The company's Chief Executive Officer, Vipin Garg, Ph.D., and Chief Medical Officer, Scott Harris, M.D., will take part in a fireside chat during the event.
The presentation is scheduled for Monday, October 7, 2024, at 11:30 a.m. EDT. Interested parties can access the webcast of the session by visiting the Events section of the Altimmune website. This participation provides an opportunity for the company to share insights and updates with investors and industry professionals in a virtual setting.
Altimmune (Nasdaq: ALT) has completed enrollment in its Phase 2b IMPACT trial, evaluating pemvidutide for metabolic dysfunction-associated steatohepatitis (MASH). The trial includes approximately 190 subjects, with top-line efficacy data expected in Q2 2025. An End-of-Phase 2 Meeting with the FDA for the obesity program is scheduled for early November 2024.
The company plans to submit Investigational New Drug (IND) applications for pemvidutide in up to three additional indications starting in Q4 2024. Altimmune aims to expand pemvidutide's differentiation in the metabolic disease space and enhance its long-term value proposition. The IMPACT trial is notable as the first incretin-based study to evaluate a biopsy-driven fibrosis endpoint at 24 weeks.
Altimmune presented results from a Phase 2 MRI-based body composition sub-study of pemvidutide at the 60th Annual Meeting of the European Association for the Study of Diabetes. The study, involving 67 subjects from the MOMENTUM obesity trial, showed promising outcomes for pemvidutide, a novel GLP-1/glucagon dual receptor agonist:
1. Lean loss ratio of only 21.9%, indicating excellent preservation of lean mass.
2. Even better lean mass preservation in subjects aged 60+, with a lean loss ratio of 19.9%.
3. 25.6% reduction in visceral adipose tissue (VAT) at the 2.4mg dose, compared to 20.1% loss in subcutaneous adipose tissue.
These results suggest pemvidutide's potential in reducing fall and fracture risks, especially in older adults, while also lowering cardiovascular disease risk through VAT reduction.
