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Aileron Therapeutics to be Included in the Russell Microcap® Index

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Aileron Therapeutics (NASDAQ: ALRN), a biopharmaceutical company focusing on orphan pulmonary and fibrosis indications, announced that it will be included in the Russell Microcap® Index. This inclusion will take effect on July 1, 2024, following the annual reconstitution of Russell U.S. Indexes, which ranks the 4,000 largest U.S. stocks by market capitalization. Membership in the Russell Microcap® Index means automatic inclusion in applicable growth and value style indexes, and will last for one year.

Aileron's inclusion is attributed to the clinical progress of its lead asset, LTI-03, for idiopathic pulmonary fibrosis, with positive data from a Phase 1b trial. Russell indexes are benchmarks for about $10.5 trillion in assets and are widely used by investment managers and institutional investors.

Positive
  • Inclusion in the Russell Microcap® Index increases visibility and credibility for Aileron Therapeutics.
  • The company's lead asset, LTI-03, has shown positive data in a Phase 1b trial, achieving statistical significance in three out of eight biomarkers.
Negative
  • None.

AUSTIN, Texas, July 1, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron" or the "Company") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that the Company is set to join the Russell Microcap® Index at the conclusion of the 2024 Russell U.S. Indexes annual reconstitution, effective at the open of US equity markets on Monday, July 1, 2024.

The annual Russell U.S. Indexes reconstitution captures the 4,000 largest U.S. stocks as of Tuesday, April 30th, ranking them by total market capitalization. Membership in the Russell Microcap® Index, which remains in place for one year, means automatic inclusion in the appropriate growth and value style indexes. FTSE Russell determines membership for its Russell indexes primarily by objective, market-capitalization rankings and style attributes.

"Aileron's inclusion in the Russell Microcap Index is an exciting step in the Company's evolution, and representative of the clinical progress made for our lead asset, LTI-03, in patients with idiopathic pulmonary fibrosis," said Brian Windsor, Ph.D., President and Chief Executive Officer of Aileron. "This increased exposure highlights our positive data reported from Cohort 1 of the Phase 1b trial which included biomarker movement which achieved statistical significance in three out of eight markers that reinforce the potential of LTI-03 to improve lung function and reverse the course of the disease."

Russell indexes are widely used by investment managers and institutional investors for index funds and as benchmarks for active investment strategies. Russell's U.S. indexes serve as the benchmark for about $10.5 trillion in assets as of the close of December 2023. Russell indexes are part of FTSE Russell, a leading global index provider.

For more information on the Russell Microcap® Index and the Russell indexes reconstitution, go to the "Russell Reconstitution" section on the FTSE Russell website.

About Aileron Therapeutics

Aileron Therapeutics, Inc. is a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications. Aileron's lead product candidate, LTI-03, is a novel, synthetic peptide with a dual mechanism targeting alveolar epithelial cell survival as well as inhibition of profibrotic signaling. Currently, LTI-03 is being evaluated in a Phase 1b clinical trial for the treatment of idiopathic pulmonary fibrosis. Aileron's second product candidate, LTI-01, is a proenzyme that has completed Phase 1b and Phase 2a clinical trials for the treatment of loculated pleural effusions. LTI-01 has received Orphan Drug Designation in the US and EU and Fast Track Designation in the US.

About FTSE Russell
FTSE Russell is a leading global provider of benchmarking, analytics, and data solutions for investors, giving them a precise view of the market relevant to their investment process. A comprehensive range of reliable and accurate indexes provides investors worldwide with the tools they require to measure and benchmark markets across asset classes, styles, or strategies.

FTSE Russell index expertise and products are used extensively by institutional and retail investors globally. For over 30 years, leading asset owners, asset managers, ETF providers and investment banks have chosen FTSE Russell indexes to benchmark their investment performance and create ETFs, structured products, and index-based derivatives.

FTSE Russell is focused on applying the highest industry standards in index design and governance, employing transparent rules-based methodology informed by independent committees of leading market participants. FTSE Russell fully embraces the IOSCO Principles, and its Statement of Compliance has received independent assurance. Index innovation is driven by client needs and customer partnerships, allowing FTSE Russell to continually enhance the breadth, depth and reach of its offering.

FTSE Russell is wholly owned by London Stock Exchange Group.

For more information, visit https://www.lseg.com/en/ftse-russell

Investor Relations & Media Contact:

Argot Partners 
aileron@argotpartners.com 
212-600-1902 

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SOURCE AILERON THERAPEUTICS

FAQ

What does Aileron Therapeutics' inclusion in the Russell Microcap® Index mean?

Aileron Therapeutics' inclusion in the Russell Microcap® Index means the company will be automatically included in the applicable growth and value style indexes, increasing its visibility and credibility among investors.

When will Aileron Therapeutics be included in the Russell Microcap® Index?

Aileron Therapeutics will be included in the Russell Microcap® Index at the open of U.S. equity markets on July 1, 2024.

Why is Aileron Therapeutics being included in the Russell Microcap® Index?

Aileron Therapeutics is being included due to its market-capitalization ranking among the 4,000 largest U.S. stocks as of April 30, 2024.

What impact could Aileron Therapeutics' inclusion in the Russell Microcap® Index have on its stock?

Inclusion in the Russell Microcap® Index could increase investor interest and investment due to greater visibility and credibility.

What recent clinical progress has Aileron Therapeutics made?

Aileron Therapeutics has reported positive data from a Phase 1b trial of its lead asset, LTI-03, for idiopathic pulmonary fibrosis, achieving statistical significance in three out of eight biomarkers.

Aileron Therapeutics, Inc.

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