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Aligos Therapeutics Strengthens Senior Leadership Team with the Appointment of Hardean Achneck, MD as Chief Medical Officer

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Aligos Therapeutics (Nasdaq: ALGS) has appointed Dr. Hardean Achneck as Chief Medical Officer, effective immediately. Dr. Achneck, a seasoned clinical development executive with expertise in hepatology and infectious diseases, will lead the company's global clinical development efforts and join the Senior Leadership Team. This appointment follows Aligos' recent positive topline data for ALG-055009 in MASH subjects.

Dr. Achneck brings extensive experience from previous roles, including Senior Vice President and Head of Clinical Development at Pliant Therapeutics, and Vice President of Clinical Development and Clinical Research at Dicerna Therapeutics. He has successfully advanced liver-targeted oligonucleotide assets and has a strong background in hepatic diseases. Dr. Achneck holds an M.D. from Yale University School of Medicine and is licensed to practice medicine in the U.S. and EU.

Aligos Therapeutics (Nasdaq: ALGS) ha nominato il Dr. Hardean Achneck nuovo Direttore Medico, con effetto immediato. Il Dr. Achneck, un esperto dirigente nello sviluppo clinico con specializzazione in epatologia e malattie infettive, guiderà gli sforzi globali di sviluppo clinico dell'azienda e si unirà al Team di Leadership Senior. Questa nomina segue i recenti dati positivi ottenuti da Aligos per ALG-055009 in soggetti con MASH.

Il Dr. Achneck porta un'ampia esperienza da ruoli precedenti, tra cui Vicepresidente Senior e Capo dello Sviluppo Clinico presso Pliant Therapeutics, e Vicepresidente dello Sviluppo Clinico e della Ricerca Clinica presso Dicerna Therapeutics. Ha promosso con successo asset oligonucleotidici mirati al fegato e ha un solido background nelle malattie epatiche. Il Dr. Achneck possiede un M.D. presso la Yale University School of Medicine ed è autorizzato a praticare la medicina negli Stati Uniti e nell'UE.

Aligos Therapeutics (Nasdaq: ALGS) ha nombrado al Dr. Hardean Achneck como Director Médico, con efecto inmediato. El Dr. Achneck, un experimentado ejecutivo en desarrollo clínico con experiencia en hepatología y enfermedades infecciosas, liderará los esfuerzos globales de desarrollo clínico de la compañía y se unirá al Equipo de Liderazgo Sénior. Esta designación sigue a los recientes datos positivos de Aligos para ALG-055009 en sujetos con MASH.

El Dr. Achneck aporta una amplia experiencia de roles anteriores, incluidos Vicepresidente Senior y Jefe de Desarrollo Clínico en Pliant Therapeutics, y Vicepresidente de Desarrollo Clínico e Investigación Clínica en Dicerna Therapeutics. Ha avanzado con éxito activos de oligonucleótidos dirigidos al hígado y tiene una sólida formación en enfermedades hepáticas. El Dr. Achneck tiene un M.D. de la Yale University School of Medicine y está autorizado para ejercer la medicina en EE. UU. y la UE.

알리고스 치료제 (Nasdaq: ALGS)는 하르딘 아크넥 박사를 최고 의료 책임자로 즉시 임명했습니다. 아크넥 박사는 간질환 및 감염병에 대한 전문 지식을 가진 경험 많은 임상 개발 임원으로, 회사의 글로벌 임상 개발 노력을 이끌고 선임 리더십 팀에 합류할 것입니다. 이번 임명은 알리고스가 MASH 수치에서 ALG-055009에 대한 최근의 긍정적인 최종 데이터를 발표한 후 이루어졌습니다.

아크넥 박사는 Pliant Therapeutics의 임상 개발 수석 부사장 및 책임자를 포함한 이전 역할에서 광범위한 경험을 가져오며, Dicerna Therapeutics에서 임상 개발 및 임상 연구 부사장을 역임했습니다. 그는 간에 타겟팅된 올리고뉴클레오타이드 자산을 성공적으로 발전시켰으며, 간 질환에 대한 강력한 배경을 가지고 있습니다. 아크넥 박사는 예일 대학교 의과대학에서 M.D.를 받았으며, 미국 및 EU에서 의사의 면허를 소지하고 있습니다.

Aligos Therapeutics (Nasdaq: ALGS) a nommé le Dr Hardean Achneck en tant que Directeur Médical, avec effet immédiat. Le Dr Achneck, un cadre expérimenté en développement clinique avec une expertise en hépatologie et en maladies infectieuses, dirigera les efforts mondiaux de développement clinique de l'entreprise et rejoindra l'équipe de direction senior. Cette nomination fait suite aux récents résultats positifs d'Aligos pour ALG-055009 chez les patients MASH.

Le Dr Achneck apporte une vaste expérience de ses précédents postes, notamment Vice-Président senior et Responsable du développement clinique chez Pliant Therapeutics, et Vice-Président du développement clinique et de la recherche clinique chez Dicerna Therapeutics. Il a réussi à faire progresser des actifs d'oligonucleotides ciblant le foie et possède une solide expérience en maladies hépatiques. Le Dr Achneck détient un M.D. de la Yale University School of Medicine et est autorisé à exercer la médecine aux États-Unis et dans l'UE.

Aligos Therapeutics (Nasdaq: ALGS) hat Dr. Hardean Achneck als Chief Medical Officer mit sofortiger Wirkung ernannt. Dr. Achneck, ein erfahrener leitender Angestellter im klinischen Bereich mit Fachkenntnissen in Hepatologie und Infektionskrankheiten, wird die globalen klinischen Entwicklungsbemühungen des Unternehmens leiten und dem Senior Leadership Team beitreten. Diese Ernennung erfolgt nach den kürzlich positiven Topline-Daten von Aligos zu ALG-055009 bei MASH-Patienten.

Dr. Achneck bringt umfassende Erfahrungen aus früheren Positionen mit, darunter Senior Vice President und Leiter der klinischen Entwicklung bei Pliant Therapeutics sowie Vice President für klinische Entwicklung und klinische Forschung bei Dicerna Therapeutics. Er hat erfolgreich leberspezifische Oligonukleotid-Ressourcen weiterentwickelt und hat einen soliden Hintergrund in Hepatologischen Erkrankungen. Dr. Achneck hat einen M.D. von der Yale University School of Medicine und ist in den USA und der EU als Arzt lizenziert.

Positive
  • Appointment of experienced Chief Medical Officer with expertise in liver indications
  • Recent positive topline data for ALG-055009 in MASH subjects
  • Strengthening of senior leadership team to progress towards later stage clinical development
Negative
  • None.

SOUTH SAN FRANCISCO, Calif., Sept. 24, 2024 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on improving patient outcomes through best-in-class therapies for liver and viral diseases, today announced the appointment of Dr. Hardean Achneck as Chief Medical Officer, effective immediately. Dr. Achneck will lead the Company’s global clinical development efforts and serve as a member of Aligos’ Senior Leadership Team. Dr. Hardean Achneck is a seasoned clinical development executive with extensive experience across multiple therapeutic areas, including hepatology and infectious diseases.

“I am excited to welcome Hardean to Aligos as our Chief Medical Officer, with expertise across liver indications, including both MASH and CHB,” said Lawrence Blatt, Ph.D., MBA, Chairman, President, and Chief Executive Officer of Aligos Therapeutics. “Following our recent positive topline data for ALG-055009 in MASH subjects, we look forward to his strategic vision as we progress towards later stage clinical development with our best-in-class pipeline of liver and viral therapies.”

“Joining Aligos at this time is a compelling opportunity, especially after the positive Phase 2a HERALD topline data readout,” stated Hardean Achneck, MD, Chief Medical Officer at Aligos. “I look forward to partnering with the team to strategically lead the Company’s current and future clinical development with the mission to improve patient outcomes.”

Most recently, Dr. Achneck served as the Senior Vice President and Head of Clinical Development at Pliant Therapeutics (NASDAQ: PLRX) where he oversaw all clinical programs, including those in hepatic diseases. Before joining Pliant, Dr. Achneck was the Vice President of Clinical Development and Clinical Research at Dicerna Therapeutics (Nasdaq: DRNA). Following its acquisition by Novo Nordisk (NYSE: NVO; Nasdaq: Novo-B) in 2021, he continued his role at the Novo Nordisk Dicerna Transformational Research Unit. He successfully advanced liver-targeted oligonucleotide assets from early to late-stage development, notably xalnesiran for chronic hepatitis B. Prior to his tenure at Dicerna, Dr. Achneck led Medical Affairs and Clinical Development at Haemonetics Corporation (NYSE: HAE). Before this, he served as Vice President and Chief Medical Officer at Hemostemix Inc.

Prior to his industry roles, Dr. Achneck was an Assistant Professor of Surgery and in Pathology at Duke University School of Medicine, with a co-appointment as Assistant Professor of Cardiovascular & Metabolic Disorders at Duke-National University of Singapore. Dr. Achneck holds an M.D. from Yale University School of Medicine and a B.A. in Molecular Biophysics & Biochemistry, magna cum laude, from Yale University. Licensed to practice medicine in the U.S. and EU, he has authored over 30 peer-reviewed publications and was named an inventor on several patents.

About Aligos

Aligos Therapeutics, Inc. (NASDAQ: ALGS) is a clinical stage biopharmaceutical company founded with the mission to improve patient outcomes by developing best-in-class therapies for the treatment of liver and viral diseases. Aligos applies its science driven approach and deep R&D expertise to advance its purpose-built pipeline of therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) and viruses with high unmet medical need such as hepatitis B and coronaviruses.

For more information, please visit www.aligos.com or follow us on LinkedIn or X.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this press release that are not historical facts may be considered “forward-looking statements,” including without limitation, statements regarding Aligos’ financial results and performance as well as research and development activities, including regulatory status and the timing of announcements and updates relating to our regulatory filings and clinical trials. Such forward looking statements are subject to substantial risks and uncertainties that could cause our development programs, future results, performance, or achievements to differ materially from those anticipated in the forward-looking statements. Such risks and uncertainties include, without limitation, risks and uncertainties inherent in the drug development process, including Aligos’ clinical-stage of development, the process of designing and conducting clinical trials, the regulatory approval processes, and other matters that could affect the sufficiency of Aligos’ capital resources to fund operations. For a further description of the risks and uncertainties that could cause actual results to differ from those anticipated in these forward-looking statements, as well as risks relating to the business of Aligos in general, see Aligos’ Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 6, 2024 and its future periodic reports to be filed or submitted with the Securities and Exchange Commission. Except as required by law, Aligos undertakes no obligation to update any forward-looking statements to reflect new information, events or circumstances, or to reflect the occurrence of unanticipated events.  
        
Aligos Therapeutics

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jtarazi@aligos.com

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FAQ

Who is the new Chief Medical Officer of Aligos Therapeutics (ALGS)?

Dr. Hardean Achneck has been appointed as the new Chief Medical Officer of Aligos Therapeutics (ALGS), effective immediately.

What is Dr. Hardean Achneck's background before joining Aligos Therapeutics (ALGS)?

Dr. Achneck previously served as Senior Vice President and Head of Clinical Development at Pliant Therapeutics and Vice President of Clinical Development and Clinical Research at Dicerna Therapeutics. He has extensive experience in hepatology and infectious diseases.

What recent positive data did Aligos Therapeutics (ALGS) report?

Aligos Therapeutics (ALGS) recently reported positive topline data for ALG-055009 in MASH (Metabolic dysfunction-Associated SteatoHepatitis) subjects.

What is the focus of Aligos Therapeutics (ALGS)?

Aligos Therapeutics (ALGS) is a clinical stage biopharmaceutical company focused on improving patient outcomes through best-in-class therapies for liver and viral diseases.

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Biotechnology
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