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AbbVie Reports First-Quarter 2025 Financial Results

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AbbVie (ABBV) reported strong Q1 2025 financial results with worldwide net revenues of $13.343 billion, up 8.4% on a reported basis. The company's immunology portfolio led growth with revenues of $6.264 billion (+16.6%), driven by Skyrizi ($3.425 billion, +70.5%) and Rinvoq ($1.718 billion, +57.2%). Neuroscience portfolio revenues increased 16.1% to $2.282 billion.

Q1 diluted EPS was $0.72 on a GAAP basis (-6.5%) and adjusted diluted EPS was $2.46 (+6.5%). The company raised its 2025 adjusted diluted EPS guidance from $11.99-$12.19 to $12.09-$12.29. Notable developments include FDA approval of Emblaveo for complicated intra-abdominal infections and entrance into the obesity treatment field through a partnership with Gubra.

AbbVie (ABBV) ha riportato solidi risultati finanziari nel primo trimestre 2025 con ricavi netti globali di 13,343 miliardi di dollari, in crescita dell'8,4% su base dichiarata. Il portafoglio di immunologia ha guidato la crescita con ricavi pari a 6,264 miliardi di dollari (+16,6%), trainati da Skyrizi (3,425 miliardi di dollari, +70,5%) e Rinvoq (1,718 miliardi di dollari, +57,2%). I ricavi del portafoglio neuroscienze sono aumentati del 16,1% raggiungendo 2,282 miliardi di dollari.

L'EPS diluito del primo trimestre è stato di 0,72 dollari su base GAAP (-6,5%) mentre l'EPS diluito rettificato è stato di 2,46 dollari (+6,5%). L'azienda ha rivisto al rialzo le previsioni per l'EPS diluito rettificato 2025, portandolo da 11,99-12,19 dollari a 12,09-12,29 dollari. Tra gli sviluppi più importanti si segnalano l'approvazione FDA di Emblaveo per le infezioni intra-addominali complicate e l'ingresso nel campo del trattamento dell'obesità tramite una partnership con Gubra.

AbbVie (ABBV) reportó sólidos resultados financieros para el primer trimestre de 2025 con ingresos netos mundiales de 13,343 millones de dólares, un aumento del 8.4% en términos reportados. La cartera de inmunología lideró el crecimiento con ingresos de 6,264 millones de dólares (+16.6%), impulsados por Skyrizi (3,425 millones de dólares, +70.5%) y Rinvoq (1,718 millones de dólares, +57.2%). Los ingresos de la cartera de neurociencia aumentaron un 16.1% hasta 2,282 millones de dólares.

El BPA diluido del primer trimestre fue de 0.72 dólares según GAAP (-6.5%) y el BPA diluido ajustado fue de 2.46 dólares (+6.5%). La compañía elevó su pronóstico de BPA diluido ajustado para 2025 de 11.99-12.19 dólares a 12.09-12.29 dólares. Entre los desarrollos destacados se incluye la aprobación de la FDA para Emblaveo para infecciones intraabdominales complicadas y la entrada en el campo del tratamiento de la obesidad mediante una asociación con Gubra.

AbbVie (ABBV)는 2025년 1분기 강력한 실적을 발표하며 전 세계 순매출이 133억 4,300만 달러로 전년 대비 8.4% 증가했습니다. 면역학 포트폴리오가 성장을 주도했으며 매출은 62억 6,400만 달러(+16.6%)로, Skyrizi(34억 2,500만 달러, +70.5%)와 Rinvoq(17억 1,800만 달러, +57.2%)가 견인했습니다. 신경과학 포트폴리오 매출은 22억 8,200만 달러로 16.1% 증가했습니다.

1분기 희석 주당순이익(EPS)은 GAAP 기준 0.72달러(-6.5%)였으며, 조정 희석 EPS는 2.46달러(+6.5%)였습니다. 회사는 2025년 조정 희석 EPS 가이던스를 기존 11.99~12.19달러에서 12.09~12.29달러로 상향 조정했습니다. 주요 개발 사항으로는 복잡한 복강내 감염 치료제 Emblaveo의 FDA 승인과 Gubra와의 파트너십을 통한 비만 치료 분야 진출이 포함됩니다.

AbbVie (ABBV) a annoncé de solides résultats financiers pour le premier trimestre 2025 avec un chiffre d'affaires net mondial de 13,343 milliards de dollars, en hausse de 8,4 % en données publiées. Le portefeuille immunologie a mené la croissance avec des revenus de 6,264 milliards de dollars (+16,6 %), portés par Skyrizi (3,425 milliards de dollars, +70,5 %) et Rinvoq (1,718 milliard de dollars, +57,2 %). Les revenus du portefeuille neurosciences ont augmenté de 16,1 % pour atteindre 2,282 milliards de dollars.

Le BPA dilué du premier trimestre s'est élevé à 0,72 dollar selon les normes GAAP (-6,5 %) et le BPA dilué ajusté à 2,46 dollars (+6,5 %). La société a relevé ses prévisions de BPA dilué ajusté pour 2025, passant de 11,99-12,19 dollars à 12,09-12,29 dollars. Parmi les développements notables figurent l'approbation par la FDA d'Emblaveo pour les infections intra-abdominales compliquées et l'entrée dans le domaine du traitement de l'obésité grâce à un partenariat avec Gubra.

AbbVie (ABBV) meldete starke Finanzergebnisse für das erste Quartal 2025 mit weltweiten Nettoumsätzen von 13,343 Milliarden US-Dollar, was einem Anstieg von 8,4 % auf Berichtsbasis entspricht. Das Immunologie-Portfolio trieb das Wachstum mit Umsätzen von 6,264 Milliarden US-Dollar (+16,6 %) an, getragen von Skyrizi (3,425 Milliarden US-Dollar, +70,5 %) und Rinvoq (1,718 Milliarden US-Dollar, +57,2 %). Die Umsätze des Neurowissenschafts-Portfolios stiegen um 16,1 % auf 2,282 Milliarden US-Dollar.

Das verwässerte Ergebnis je Aktie (EPS) im ersten Quartal betrug 0,72 US-Dollar auf GAAP-Basis (-6,5 %), das bereinigte verwässerte EPS lag bei 2,46 US-Dollar (+6,5 %). Das Unternehmen hob seine Prognose für das bereinigte verwässerte EPS 2025 von 11,99-12,19 US-Dollar auf 12,09-12,29 US-Dollar an. Zu den bemerkenswerten Entwicklungen zählen die FDA-Zulassung von Emblaveo für komplizierte intraabdominale Infektionen und der Einstieg in den Bereich der Adipositas-Behandlung durch eine Partnerschaft mit Gubra.

Positive
  • Strong revenue growth of 8.4% to $13.343 billion
  • Immunology portfolio growth of 16.6% led by Skyrizi (+70.5%) and Rinvoq (+57.2%)
  • Neuroscience portfolio growth of 16.1% to $2.282 billion
  • Raised full-year 2025 EPS guidance
  • Expansion into obesity treatment market through Gubra partnership
Negative
  • GAAP EPS decreased 6.5% to $0.72
  • Humira revenues declined 50.6% to $1.121 billion
  • Aesthetics portfolio declined 11.7%
  • Imbruvica revenues decreased 11.9% to $738 million

Insights

Strong Q1 with 8.4% revenue growth and raised 2025 guidance, as Skyrizi and Rinvoq growth offsets Humira decline.

AbbVie delivered impressive first-quarter results with revenues of $13.343 billion, increasing 8.4% year-over-year on a reported basis and 9.8% on an operational basis. These results exceeded management's expectations, prompting a guidance raise for 2025.

The company's adjusted diluted EPS grew 6.5% to $2.46, despite absorbing a $0.13 per share impact from acquired IPR&D and milestone expenses. Management has increased its full-year 2025 EPS guidance from $11.99-$12.19 to $12.09-$12.29, signaling confidence in continued performance.

AbbVie's portfolio transformation is successfully navigating the Humira patent cliff. While Humira revenues declined 50.6% to $1.121 billion, this was more than offset by stellar performance from newer immunology assets. Skyrizi generated $3.425 billion (+70.5%) and Rinvoq reached $1.718 billion (+57.2%), collectively driving the immunology portfolio to $6.264 billion (+16.6%).

Profitability metrics remain robust with an adjusted gross margin of 84.1% and adjusted operating margin of 42.3%. R&D investment remains significant at 15.4% of revenues on an adjusted basis, supporting future growth.

The neuroscience portfolio showed strong momentum at $2.282 billion (+16.1%), with Vraylar, Botox Therapeutic, and migraine treatments Ubrelvy and Qulipta all delivering double-digit growth. Oncology revenues grew more modestly at 5.8% to $1.633 billion, with Venclexta growth and Elahere contribution offsetting Imbruvica decline.

The only notable weakness was in the aesthetics portfolio, which declined 11.7% to $1.102 billion, with both Botox Cosmetic and Juvederm showing double-digit decreases. This suggests continued softness in the discretionary aesthetics market.

AbbVie successfully transitioning beyond Humira with immunology growth drivers, strategic pipeline expansions, and entry into obesity market.

AbbVie's Q1 results demonstrate the successful execution of its post-Humira strategy. The company has established Skyrizi and Rinvoq as powerful growth drivers, with combined quarterly sales surpassing $5.1 billion – more than four times Humira's current revenue. This transformation validates the company's strategic focus on immunology leadership beyond Humira.

Recent regulatory milestones strengthen AbbVie's market position. The European Commission approval of Rinvoq for giant cell arteritis marks its eighth indication in the EU, showcasing the drug's expanding therapeutic potential. Meanwhile, the FDA approval of Emblaveo as the first monobactam/β-lactamase inhibitor combination for complicated intra-abdominal infections addresses an important unmet need in serious bacterial infections.

The Elahere data presented at the Society of Gynecologic Oncology meeting reinforces its efficacy in folate receptor alpha-positive platinum-resistant ovarian cancer, showing significant improvements in both progression-free survival and overall survival compared to chemotherapy. This strengthens AbbVie's position in targeted oncology therapeutics.

Strategically significant is AbbVie's entrance into the obesity market through its Gubra partnership for GUB014295, a long-acting amylin analog. With positive Phase 1 multiple ascending dose data showing sustained weight loss, this represents AbbVie's calculated move into one of healthcare's fastest-growing therapeutic areas.

The company continues innovating in its aesthetics business despite current market headwinds, with the FDA submission for trenibotulinumtoxinE potentially creating a first-in-class neurotoxin with rapid onset (8 hours) for patients seeking more immediate results. The planned expansion of Allergan Medical Institute training centers in the US also demonstrates continued long-term investment in this business segment.

AbbVie's diversified portfolio strategy across immunology, neuroscience, oncology, aesthetics and now obesity positions it for sustained growth beyond the Humira transition period.

  • Reports First-Quarter Diluted EPS of $0.72 on a GAAP Basis, a Decrease of 6.5 Percent; Adjusted Diluted EPS of $2.46, an Increase of 6.5 Percent; These Results Include an Unfavorable Impact of $0.13 Per Share Related to Acquired IPR&D and Milestones Expense 
     
  • Delivers First-Quarter Net Revenues of $13.343 Billion, an Increase of 8.4 Percent on a Reported Basis or 9.8 Percent on an Operational Basis 
     
  • First-Quarter Global Net Revenues from the Immunology Portfolio Were $6.264 Billion, an Increase of 16.6 Percent on a Reported Basis, or 18.1 Percent on an Operational Basis; Global Skyrizi Net Revenues Were $3.425 Billion; Global Rinvoq Net Revenues Were $1.718 Billion; Global Humira Net Revenues Were $1.121 Billion 
     
  • First-Quarter Global Net Revenues from the Neuroscience Portfolio Were $2.282 Billion, an Increase of 16.1 Percent on a Reported Basis, or 17.0 Percent on an Operational Basis; Global Vraylar Net Revenues Were $765 Million; Global Botox Therapeutic Net Revenues Were $866 Million; Combined Global Ubrelvy and Qulipta Net Revenues Were $433 Million 
     
  • First-Quarter Global Net Revenues from the Oncology Portfolio Were $1.633 Billion, an Increase of 5.8 Percent on a Reported Basis, or 7.5 Percent on an Operational Basis; Global Imbruvica Net Revenues Were $738 Million; Global Venclexta Net Revenues Were $665 Million; Global Elahere Net Revenues Were $179 Million
     
  • First-Quarter Global Net Revenues from the Aesthetics Portfolio Were $1.102 Billion, a Decrease of 11.7 Percent on a Reported Basis, or 10.2 Percent on an Operational Basis; Global Botox Cosmetic Net Revenues Were $556 Million; Global Juvederm Net Revenues Were $231 Million
     
  • Raises 2025 Adjusted Diluted EPS Guidance Range from $11.99 - $12.19 to $12.09 - $12.29, which Includes an Unfavorable Impact of $0.13 Per Share Related to Acquired IPR&D and Milestones Expense Incurred Year-To-Date Through the First Quarter 2025

NORTH CHICAGO, Ill., April 25, 2025 /PRNewswire/ -- AbbVie (NYSE:ABBV) announced financial results for the first quarter ended March 31, 2025.

"AbbVie's first-quarter results were well ahead of our expectations and reflect an excellent start to the year," said Robert A. Michael, chief executive officer, AbbVie. "The fundamentals of our business are strong and we continue to bolster our outlook with pipeline advancements and strategic investments. Based on the progress we are making, AbbVie is well positioned for the long term."

First-Quarter Results

  • Worldwide net revenues were $13.343 billion, an increase of 8.4 percent on a reported basis, or 9.8 percent on an operational basis.
     
  • Global net revenues from the immunology portfolio were $6.264 billion, an increase of 16.6 percent on a reported basis, or 18.1 percent on an operational basis.
    • Global Skyrizi net revenues were $3.425 billion, an increase of 70.5 percent on a reported basis, or 72.0 percent on an operational basis.
    • Global Rinvoq net revenues were $1.718 billion, an increase of 57.2 percent on a reported basis, or 59.7 percent on an operational basis.
    • Global Humira net revenues were $1.121 billion, a decrease of 50.6 percent on a reported basis, or 49.5 percent on an operational basis.
       
  • Global net revenues from the neuroscience portfolio were $2.282 billion, an increase of 16.1 percent on a reported basis, or 17.0 percent on an operational basis.
    • Global Vraylar net revenues were $765 million, an increase of 10.3 percent.
    • Global Botox Therapeutic net revenues were $866 million, an increase of 15.8 percent on a reported basis, or 17.0 percent on an operational basis.
    • Global Ubrelvy net revenues were $240 million, an increase of 17.8 percent on a reported basis, or 18.0 percent on an operational basis.
    • Global Qulipta net revenues were $193 million, an increase of 47.6 percent on a reported basis, or 48.3 percent on an operational basis.
       
  • Global net revenues from the oncology portfolio were $1.633 billion, an increase of 5.8 percent on a reported basis, or 7.5 percent on an operational basis.
    • Global Imbruvica net revenues were $738 million, a decrease of 11.9 percent.
    • Global Venclexta net revenues were $665 million, an increase of 8.3 percent on a reported basis, or 12.3 percent on an operational basis.
    • Global Elahere net revenues were $179 million.
       
  • Global net revenues from the aesthetics portfolio were $1.102 billion, a decrease of 11.7 percent on a reported basis, or 10.2 percent on an operational basis.
    • Global Botox Cosmetic net revenues were $556 million, a decrease of 12.3 percent on a reported basis, or 10.7 percent on an operational basis.
    • Global Juvederm net revenues were $231 million, a decrease of 22.2 percent on a reported basis, or 20.0 percent on an operational basis.
       
  • On a GAAP basis, gross margin in the first quarter was 70.0 percent. The adjusted gross margin was 84.1 percent.
     
  • On a GAAP basis, selling, general and administrative (SG&A) expense was 24.7 percent of net revenues. The adjusted SG&A expense was 24.6 percent of net revenues.
     
  • On a GAAP basis, research and development (R&D) expense was 15.5 percent of net revenues. The adjusted R&D expense was 15.4 percent of net revenues.
     
  • Acquired IPR&D and milestones expense was 1.9 percent of net revenues.
     
  • On a GAAP basis, operating margin in the first quarter was 28.0 percent. The adjusted operating margin was 42.3 percent.
     
  • Net interest expense was $627 million.
     
  • On a GAAP basis, the tax rate in the quarter was 22.4 percent. The adjusted tax rate was 14.2 percent.
     
  • Diluted EPS in the first quarter was $0.72 on a GAAP basis. Adjusted diluted EPS, excluding specified items, was $2.46. These results include an unfavorable impact of $0.13 per share related to acquired IPR&D and milestones expense.

Note: "Operational" comparisons are presented at constant currency rates that reflect comparative local currency net revenues at the prior year's foreign exchange rates. 

Recent Events

  • AbbVie announced that its board of directors unanimously elected chief executive officer (CEO) Robert A. Michael to assume the additional position of chairman of the board of directors, effective July 1, 2025. He will succeed Richard A. Gonzalez, who formerly served as AbbVie's CEO and has been chairman since the Company's formation in 2013.
     
  • AbbVie announced that the European Commission (EC) granted marketing authorization to Rinvoq (upadacitinib) for the treatment of giant cell arteritis (GCA) in adult patients. The approval was supported by data from the pivotal Phase 3 SELECT-GCA trial which demonstrated that Rinvoq achieved the primary endpoint of sustained remission and key secondary endpoints, including reduction in disease flares, lower cumulative steroid exposure and complete remission. This authorization marks the eighth approved indication for Rinvoq in the European Union (EU).
     
  • At the Society of Gynecologic Oncology (SGO) Annual Meeting, AbbVie announced final data analysis from the Phase 3 MIRASOL trial evaluating the efficacy and safety of Elahere (mirvetuximab soravtansine-gynx) in women with folate receptor alpha (FRα)-positive platinum-resistant ovarian cancer (PROC) compared to chemotherapy. At 30.5 months median follow-up, treatment with Elahere continued to show significant improvements in progression-free survival (PFS) and overall survival (OS) compared to investigator's choice (IC) chemotherapy.
     
  • AbbVie and Xilio Therapeutics, a clinical-stage biotechnology company, announced a collaboration and option-to-license agreement that will combine AbbVie's oncology expertise with Xilio's proprietary tumor-activation technology to develop novel immunotherapies, including masked T-cell engagers, for people living with cancer.
     
  • AbbVie announced that it submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of trenibotulinumtoxinE (BoNT/E) for the treatment of moderate to severe glabellar lines. TrenibotulinumtoxinE is a first-in-class botulinum neurotoxin serotype E characterized by a rapid onset of action as early as 8 hours after administration and short duration of effect of 2-3 weeks. If approved, trenibotulinumtoxinE will be the first neurotoxin of its kind available to patients.
     
  • Allergan Aesthetics announced that the Allergan Medical Institute (AMI) will open three new state-of-the-art training centers in the U.S., expanding access to high-quality, tailored training for licensed aesthetics providers. The first training center is scheduled to open in Irvine, CA, with additional locations to follow in Atlanta, GA and Austin, TX.
     
  • AbbVie and Gubra announced a license agreement to develop GUB014295 (ABBV-295), a potential best-in-class, long-acting amylin analog for the treatment of obesity. This partnership marks AbbVie's entrance into the obesity field and under the terms of the agreement, AbbVie will lead development and commercialization of GUB014295 globally. Prior to the close of the agreement, Gubra announced positive interim results from Part A of a Phase 1 multiple ascending dose (MAD) study, which showed that GUB014295 was well tolerated with body weight loss that was sustained in a manner consistent with data from a previously announced single ascending dose (SAD) study.
     
  • AbbVie announced that the FDA approved Emblaveo (aztreonam and avibactam), as the first monobactam/β-lactamase inhibitor combination antibiotic therapy to treat complicated intra-abdominal infections, including those caused by Gram-negative bacteria. The approval of Emblaveo was supported by prior findings regarding the efficacy and safety of aztreonam for the treatment of complicated intra-abdominal infections as well as clinical trial results from the Phase 3 REVISIT study, which evaluated the efficacy, safety, and tolerability of Emblaveo for the treatment of serious infections due to Gram-negative bacteria.

Full-Year 2025 Outlook

AbbVie is raising its adjusted diluted EPS guidance for the full year 2025 from $11.99 - $12.19 to $12.09 - $12.29, which includes an unfavorable impact of $0.13 per share related to acquired IPR&D and milestones expense incurred year-to-date through the first quarter 2025. The company's 2025 adjusted diluted EPS guidance excludes any impact from acquired IPR&D and milestones that may be incurred beyond the first quarter of 2025, as both cannot be reliably forecasted. This guidance does not reflect the acquired IPR&D and milestones impact related to AbbVie and Gubra's licensing agreement to develop GUB014295, as that transaction closed after the first quarter of 2025. Additionally, this guidance is based on the existing trade environment and does not reflect any trade policy shifts, including pharmaceutical sector tariffs, that could impact AbbVie's business.

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, neuroscience, oncology, and eye care - and products and services across our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X (formerly Twitter), Facebook, Instagram, YouTube or LinkedIn.

Conference Call

AbbVie will host an investor conference call today at 8:00 a.m. Central Time to discuss our first-quarter performance. The call will be webcast through AbbVie's Investor Relations website at investors.abbvie.com. An archived edition of the call will be available after 11:00 a.m. Central Time.

Non-GAAP Financial Results

Financial results for 2025 and 2024 are presented on both a reported and a non-GAAP basis. Reported results were prepared in accordance with GAAP and include all revenue and expenses recognized during the period. Non-GAAP results adjust for certain non-cash items and for factors that are unusual or unpredictable, and exclude those costs, expenses, and other specified items presented in the reconciliation tables later in this release. AbbVie's management believes non-GAAP financial measures provide useful information to investors regarding AbbVie's results of operations and assist management, analysts, and investors in evaluating the performance of the business. Non-GAAP financial measures should be considered in addition to, and not as a substitute for, measures of financial performance prepared in accordance with GAAP.

Forward-Looking Statements

Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry, the impact of global macroeconomic factors, such as economic downturns or uncertainty, international conflict, trade disputes and tariffs, and other uncertainties and risks associated with global business operations. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2024 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its Quarterly Reports on Form 10-Q and in other documents that AbbVie subsequently files with the Securities and Exchange Commission that update, supplement or supersede such information. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law.

Media:

Investors:

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Liz Shea

(224) 244-0111

(847) 935-2211




Todd Bosse


(847) 936-1182




Jeffrey Byrne


(847) 938-2923

 

AbbVie Inc.

Key Product Revenues

Quarter Ended March 31, 2025

(Unaudited)









% Change vs. 1Q24


Net Revenues (in millions)


Reported


Operationala


U.S.


Int'l.


Total


U.S.


Int'l.


Total


Int'l.


Total

NET REVENUES

$9,979


$3,364


$13,343


10.4 %


2.9 %


8.4 %


8.3 %


9.8 %

















Immunology

4,883


1,381


6,264


17.6


13.4


16.6


20.1


18.1

Skyrizi

2,919


506


3,425


76.2


43.9


70.5


52.3


72.0

Rinvoq

1,220


498


1,718


68.3


35.3


57.2


42.8


59.7

Humira

744


377


1,121


(58.0)


(24.4)


(50.6)


(19.5)


(49.5)

















Neuroscience

1,972


310


2,282


15.0


24.0


16.1


31.0


17.0

Vraylar

763


2


765


10.3


13.1


10.3


20.2


10.3

Botox Therapeutic

723


143


866


18.2


4.8


15.8


11.4


17.0

Ubrelvy

233


7


240


17.6


23.3


17.8


29.3


18.0

Qulipta

172


21


193


34.2


>100.0


47.6


>100.0


48.3

Vyalev

6


57


63


n/m


>100.0


>100.0


>100.0


>100.0

Duodopa

20


76


96


(19.4)


(16.0)


(16.7)


(11.7)


(13.3)

Other Neuroscience

55


4


59


(9.5)


(1.0)


(8.9)


6.5


(8.4)

















Oncology

1,027


606


1,633


6.0


5.4


5.8


10.0


7.5

Imbruvicab

529


209


738


(13.3)


(8.2)


(11.9)


(8.2)


(11.9)

Venclexta

312


353


665


11.0


6.0


8.3


13.4


12.3

Elahere

165


14


179


>100.0


n/m


>100.0


n/m


>100.0

Epkinlyc

21


30


51


66.7


>100.0


89.8


>100.0


94.8

















Aesthetics

640


462


1,102


(17.4)


(2.4)


(11.7)


1.6


(10.2)

Botox Cosmetic

295


261


556


(24.3)


6.9


(12.3)


11.1


(10.7)

Juvederm Collection

75


156


231


(29.0)


(18.5)


(22.2)


(15.0)


(20.0)

Other Aesthetics

270


45


315


(3.5)


18.1


(0.9)


23.2


(0.3)

















Eye Care

221


285


506


(2.6)


(8.0)


(5.7)


(2.0)


(2.2)

Ozurdex

30


93


123


(12.1)


(3.8)


(6.0)


1.1


(2.4)

Lumigan/Ganfort

48


58


106


69.2


(6.8)


17.0


(0.5)


21.4

Alphagan/Combigan

26


34


60


68.5


(21.4)


1.9


(15.4)


6.3

Other Eye Care

117


100


217


(21.4)


(7.1)


(15.4)


(0.2)


(12.5)

















Other Key Products

636


173


809


(7.2)


(19.4)


(10.1)


(14.8)


(9.0)

Mavyret

142


164


306


(0.7)


(20.4)


(12.3)


(15.8)


(9.6)

Creon

355



355


24.6


n/m


24.6


n/m


24.6

Linzess/Constella

139


9


148


(46.1)


3.1


(44.4)


9.3


(44.2)



a

"Operational" comparisons are presented at constant currency rates that reflect comparative local currency net revenues at the prior year's foreign exchange rates.

b

Reflects profit sharing for Imbruvica international revenues.

c

Epkinly U.S. revenues reflect profit sharing. International revenues reflect product revenues as well as profit sharing from certain international territories.

n/m = not meaningful

 

AbbVie Inc.

Consolidated Statements of Earnings

(Unaudited)


(in millions, except per share data)


 First Quarter

Ended March 31



2025


2024

Net revenues


$       13,343


$        12,310

Cost of products sold


4,002


4,094

Selling, general and administrative


3,293


3,315

Research and development


2,067


1,939

Acquired IPR&D and milestones


248


164

Total operating costs and expenses


9,610


9,512






Operating earnings


3,733


2,798






Interest expense, net


627


453

Net foreign exchange loss


4


4

Other expense, net


1,441


586

Earnings before income tax expense


1,661


1,755

Income tax expense


372


383

Net earnings


1,289


1,372

Net earnings attributable to noncontrolling interest


3


3

Net earnings attributable to AbbVie Inc.


$          1,286


$          1,369






Diluted earnings per share attributable to AbbVie Inc.                                                         


$            0.72


$            0.77






Adjusted diluted earnings per sharea


$            2.46


$            2.31






Weighted-average diluted shares outstanding


1,772


1,773



a

Refer to the Reconciliation of GAAP Reported to Non-GAAP Adjusted Information for further details.

 

AbbVie Inc.

Reconciliation of GAAP Reported to Non-GAAP Adjusted Information

(Unaudited)


1.     Specified items impacted results as follows:



Quarter Ended March 31, 2025

(in millions, except per share data)

Earnings


Diluted


Pre-tax


After-taxa


EPS

As reported (GAAP)

$              1,661


$              1,286


$                0.72

Adjusted for specified items:






Intangible asset amortization

1,858


1,574


0.89

Change in fair value of contingent consideration                            

1,518


1,477


0.83

Other

62


33


0.02

As adjusted (non-GAAP)

$              5,099


$              4,370


$                2.46


a     Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.


Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2025 included acquired
IPR&D and milestones expense of $248 million on a pre-tax and $238 million on an after-tax basis, representing an
unfavorable impact of $0.13 to both diluted EPS and adjusted diluted EPS.


2.     The impact of the specified items by line item was as follows: 



Quarter Ended March 31, 2025

(in millions)

Cost of
products
sold


SG&A


R&D


Other
expense,
net

As reported (GAAP)

$      4,002


$      3,293


$      2,067


$      1,441

Adjusted for specified items:








Intangible asset amortization

(1,858)




Change in fair value of contingent consideration                     




(1,518)

Other

(28)


(13)


(16)


(5)

As adjusted (non-GAAP)

$      2,116


$      3,280


$      2,051


$          (82)


3.     The adjusted tax rate for the first quarter of 2025 was 14.2 percent, as detailed below:



Quarter Ended March 31, 2025

(dollars in millions)

Pre-tax
earnings


Income taxes


Tax rate

As reported (GAAP)                            

$              1,661


$                 372


22.4 %

Specified items

3,438


354


10.3 %

As adjusted (non-GAAP)                                                              

$              5,099


$                 726


14.2 %

 

AbbVie Inc.

Reconciliation of GAAP Reported to Non-GAAP Adjusted Information

(Unaudited)


1.     Specified items impacted results as follows:



Quarter Ended March 31, 2024

(in millions, except per share data)

Earnings


Diluted


Pre-tax


After-taxa


EPS

As reported (GAAP)

$              1,755


$              1,369


$                0.77

Adjusted for specified items:






Intangible asset amortization

1,891


1,603


0.90

Acquisition and integration costs

511


486


0.27

Change in fair value of contingent consideration                          

660


643


0.36

Other

21


19


0.01

As adjusted (non-GAAP)

$              4,838


$              4,120


$                2.31


 a    Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.


Acquisition and integration costs primarily reflect costs related to the ImmunoGen acquisition.


Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2024 included acquired
IPR&D and milestones expense of $164 million on a pre-tax and $138 million on an after-tax basis, representing an
unfavorable impact of $0.08 to both diluted EPS and adjusted diluted EPS.


2.     The impact of the specified items by line item was as follows: 



Quarter Ended March 31, 2024

(in millions)

Cost of
products
sold


SG&A


R&D


Interest
expense,
net


Other
expense,
net

As reported (GAAP)

$     4,094


$     3,315


$     1,939


$        453


$        586

Adjusted for specified items:










Intangible asset amortization

(1,891)





Acquisition and integration costs

(79)


(280)


(128)


(24)


Change in fair value of contingent consideration   





(660)

Other

(16)


(3)




(2)

As adjusted (non-GAAP)

$     2,108


$     3,032


$     1,811


$        429


$        (76)


3.     The adjusted tax rate for the first quarter of 2024 was 14.8 percent, as detailed below:



Quarter Ended March 31, 2024

(dollars in millions)

Pre-tax
earnings


Income taxes


Tax rate

As reported (GAAP)

$              1,755


$                 383


21.8 %

Specified items

3,083


332


10.8 %

As adjusted (non-GAAP)                                                             

$              4,838


$                 715


14.8 %

 

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SOURCE AbbVie

FAQ

What were AbbVie's (ABBV) Q1 2025 revenue and earnings results?

AbbVie reported Q1 2025 revenues of $13.343 billion (+8.4%) and adjusted diluted EPS of $2.46 (+6.5%), with GAAP EPS at $0.72.

How did AbbVie's Skyrizi and Rinvoq perform in Q1 2025?

Skyrizi revenues grew 70.5% to $3.425 billion, while Rinvoq revenues increased 57.2% to $1.718 billion in Q1 2025.

What is AbbVie's updated EPS guidance for 2025?

AbbVie raised its 2025 adjusted diluted EPS guidance to $12.09-$12.29 from previous $11.99-$12.19.

How did AbbVie's aesthetics portfolio perform in Q1 2025?

The aesthetics portfolio declined 11.7% to $1.102 billion, with Botox Cosmetic at $556 million (-12.3%) and Juvederm at $231 million (-22.2%).
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