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Zymeworks Inc. (Nasdaq: ZYME) is a global biotechnology company committed to the discovery, development, and commercialization of novel, multifunctional biotherapeutics. The company's mission is to make a meaningful difference for people impacted by difficult-to-treat cancers and other serious diseases.
Zymeworks specializes in developing best-in-class bi-specific antibodies and antibody-drug conjugates (ADCs) to treat oncology, autoimmunity, and inflammatory diseases. Their proprietary platforms, including Azymetric™, Albucore™, and ZymeLink™, enable the creation of highly potent bi-specific antibodies and multivalent protein therapeutics targeting a range of indications.
The company's leading therapeutic candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently in multiple Phase 1, Phase 2, and pivotal clinical trials globally. Zanidatamab is being developed as a targeted treatment for patients with HER2-expressing cancers. Recent milestones include the acceptance of a Biologics License Application (BLA) by the FDA and China's National Medical Products Administration (NMPA) for second-line treatment of HER2-positive biliary tract cancers (BTC).
Zymeworks is also advancing a deep preclinical pipeline, including candidates like zanidatamab zovodotin (ZW49) and new investigational drugs ZW171 and ZW191, with plans for multiple IND filings in 2024 and 2025. The company is financially robust, with a cash runway extending into the second half of 2027, bolstered by strategic partnerships with BeiGene and Jazz Pharmaceuticals, among others.
The company's complementary therapeutic platforms and fully integrated drug development engine enable precise engineering of differentiated product candidates, offering potential best-in-class treatments for various challenging diseases. For more information, visit www.zymeworks.com.
Zymeworks Inc. (Nasdaq: ZYME) presented new data from its clinical and preclinical programs at the 2023 American Association for Cancer Research Annual Meeting. Key highlights include:
- ZW191 showed strong responses in FRα-low expressing patient-derived xenograft models, with positive pharmacokinetic and safety profiles.
- ZW171 effectively killed cancer cells while mitigating risks of toxicity and adverse immune activation.
- ZW251 demonstrated significant anti-tumor activity in various glypican-3-expressing cancer models.
The company aims to advance at least five novel therapeutics into clinical studies by 2027, bolstered by their innovative antibody-drug conjugates and multispecific antibody platforms.
Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company focused on developing innovative biotherapeutics, will report its Q1 2023 financial results on May 8, 2023, after market close. Following this announcement, Zymeworks will host a conference call and webcast at 4:30 p.m. ET on the same day to discuss the results and provide a corporate update. Investors can access the live event and recordings through Zymeworks’ website.
Founded with a mission to address challenging cancers and other serious diseases, Zymeworks specializes in antibody-based therapies using its proprietary Azymetric™ technology. The company is advancing its lead candidate, zanidatamab, and next-generation product zanidatamab zovodotin (ZW49), both targeting HER2-expressing cancers.
Zymeworks Inc. (Nasdaq: ZYME) announced the appointment of Derek J. Miller to its board of directors effective April 10, 2023. Miller brings over 25 years of experience in oncology and corporate development. His expertise is expected to support Zymeworks in its collaboration efforts with Jazz Pharmaceuticals and BeiGene on zanidatamab, a bispecific antibody currently undergoing multiple clinical trials. Kenneth Galbraith, CEO, emphasized Miller's strategic insights will enhance the company's pipeline of drug candidates. Miller's previous roles include leadership positions at Aro Biotherapeutics and Celator Pharmaceuticals, where he contributed to significant collaborations and business strategies that generated substantial revenues. Zymeworks focuses on developing innovative biotherapeutics aimed at improving outcomes for patients with difficult-to-treat cancers.
Zymeworks Inc. (NASDAQ: ZYME), a clinical-stage biotechnology firm, will participate in two upcoming investor conferences. Management will hold one-on-one meetings and present at the 2023 Bloom Burton & Co. Healthcare Investor Conference on April 25 in
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