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Zai Lab Limited American Depositary Shares - ZLAB STOCK NEWS

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Zai Lab Limited (NASDAQ: ZLAB) is a pioneering biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines. Established in 2013 by industry veterans, Zai Lab addresses some of the world's most pressing unmet medical needs with a vision to transform patients’ lives globally.

The company employs a dual approach of in-licensing products and internal research and development to maintain a robust pipeline. This strategy has led to the development of promising drug candidates aimed at treating a range of severe health conditions, particularly in oncology, autoimmune, and infectious diseases.

Core Products and Pipeline:

  • ZL-2306: An investigational treatment for multiple solid tumor types, including ovarian, breast, and lung cancers.
  • ZL-2401: A novel antibiotic belonging to a new class of tetracycline derivatives, significant in the battle against resistant bacterial infections.
  • ZL-2301: An oral small molecule targeting hepatocellular carcinoma (HCC), promising for liver cancer treatment.

Zai Lab's leadership team is acclaimed for their innovative regulatory approval pathways in China, which have expedited the introduction of new therapies. The company's partnerships with global pharmaceutical giants underscore its commitment to conducting world-class clinical development both in China and internationally.

Financially, Zai Lab has strong support from a cadre of leading healthcare investors, ensuring robust backing for its ambitious projects. This financial stability allows the company to explore cutting-edge research and expand its therapeutic offerings continually.

Recent Achievements and Current Projects:

  • Successful initiation of multiple late-stage clinical trials across various therapeutic areas.
  • Establishment of strategic partnerships with multinational pharmaceutical companies to enhance drug development and commercialization.
  • Ongoing expansion of their research facilities to accommodate new projects and collaborations.

Zai Lab remains committed to leveraging its expertise, innovation, and strategic partnerships to bring life-changing therapies to market, ultimately improving patient outcomes worldwide.

Rhea-AI Summary

Zai Lab Limited (NASDAQ: ZLAB) announced the initiation of patient dosing in China for the global POD1UM-101 study, assessing retifanlimab for previously treated, microsatellite instability-high endometrial cancer. This study aims to enroll around 100 patients and primarily evaluates the overall response rate. Endometrial cancer, prevalent in China, has a significant unmet medical need, particularly for patients with high microsatellite instability. Retifanlimab is an investigational anti-PD1 antibody also being assessed for other cancers, with Orphan Drug Designation granted for anal cancer.

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On October 28, 2020, Zai Lab announced its participation in several virtual investor conferences in November. Key events include the Citi China Investor Conference on November 5, the BioCentury 7th China Healthcare Summit and Nomura Investment Forum on November 12, and the Goldman Sachs Asia Pacific Healthcare Forum on November 17, followed by the Jefferies Virtual London Healthcare Conference on November 18. A live webcast of the Jefferies conference will be available for 90 days post-event. Zai Lab aims to deliver transformative medicines for various diseases.

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Zai Lab Limited (NASDAQ: ZLAB; HKEX: 9688) has fully exercised its over-allotment option, resulting in the issuance of 1,584,600 additional shares. This represents 15% of the total number of Offer Shares available under the recent Global Offering. The shares will be priced at HK$562 each, generating approximately HK$890.55 million in gross proceeds. The Hong Kong Stock Exchange has approved the listing of these shares, scheduled to commence on October 16, 2020. Zai Lab aims to utilize the proceeds for purposes outlined in its Prospectus.

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Zai Lab announced the dosing of the first patient in Greater China for the global MAHOGANY study, evaluating margetuximab in combination with a checkpoint inhibitor for HER2-positive gastric cancer and gastroesophageal junction cancer. This Phase 2/3 trial aims to assess margetuximab’s efficacy with or without chemotherapy. Gastric cancer is prevalent, with significant unmet medical needs. Zai Lab collaborates with MacroGenics for this study, which is crucial for addressing advanced stage cancers in China, where the prognosis is often poor.

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Zai Lab Limited (NASDAQ: ZLAB) has initiated dosing of the first patient in China for the global Phase 3 POD1UM-304 study, evaluating retifanlimab alongside platinum-based chemotherapy for first-line metastatic non-small-cell lung cancer (NSCLC). The trial aims to enroll approximately 530 patients and focuses on overall survival and progression-free survival as primary endpoints. The collaboration with Incyte aims to address the significant unmet medical need for NSCLC treatment in China, where lung cancer is the leading cause of cancer deaths.

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On September 28, 2020, Zai Lab announced its secondary listing on the Hong Kong Stock Exchange (stock code: 9688), successfully closing an offering of 10,564,050 new ordinary shares at HK$562.00 per share, equating to approximately US$72.52 per American depositary share. The gross proceeds from this offering are around HK$5.94 billion before costs. The international underwriters have an over-allotment option for an additional 1,584,600 shares. Zai Lab aims to enhance its presence in the rapidly growing Chinese pharmaceutical market.

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Zai Lab Limited (NASDAQ: ZLAB) has successfully completed its secondary listing on the Hong Kong Stock Exchange under stock code '9688'. The listing involved the offering of 10,564,050 new ordinary shares at HK$562.00 per share, translating to approximately US$72.52 per American depositary share. The offering raised approximately HK$5.94 billion in gross proceeds. J.P. Morgan, Goldman Sachs, and Citigroup acted as joint sponsors and bookrunners for the listing. This strategic move aims to enhance Zai Lab’s presence in the fast-growing Asian market.

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Zai Lab (SEHK:9688, NASDAQ:ZLAB), a biopharmaceutical company, has officially listed on the Main Board of The Stock Exchange of Hong Kong Limited as of September 27, 2020. The stock opened at HK$613.5, reflecting a 9.16% increase and a market capitalization of HK$52.724 billion. Founded in 2014 with Qiming Venture Partners as its earliest investor, Zai Lab focuses on innovative treatments for cancer, infectious, and autoimmune diseases. The company has a robust pipeline of 16 products, including two already commercialized in Greater China.

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Zai Lab Limited (NASDAQ: ZLAB) announced the pricing of its Hong Kong secondary listing of 10,564,050 new ordinary shares at HK$562.00, approximately US$72.52 per ADS. The gross proceeds from this listing are estimated at HK$5.94 billion, with trading beginning on September 28, 2020, subject to regulatory approval. The company plans to utilize the funds for R&D and commercialization of core products, ongoing clinical trials, and expanding its internal pipeline. Notably, Zai Lab's ADSs will continue to be traded on NASDAQ.

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Zai Lab Limited (NASDAQ: ZLAB) announced positive results from the NORA study, a Phase 3 trial showcasing niraparib as an effective maintenance therapy for patients with recurrent ovarian cancer. The treatment resulted in a 68% reduction in disease progression or death compared to placebo, with median progression-free survival of 18.3 months versus 5.4 months. An individualized dosing regimen reduced the incidence of hematological adverse events. The study's findings are critical for improving treatment standards in China.

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FAQ

What is the current stock price of Zai Lab American Depositary Shares (ZLAB)?

The current stock price of Zai Lab American Depositary Shares (ZLAB) is $26.72 as of December 20, 2024.

What is the market cap of Zai Lab American Depositary Shares (ZLAB)?

The market cap of Zai Lab American Depositary Shares (ZLAB) is approximately 2.8B.

What does Zai Lab Limited specialize in?

Zai Lab Limited focuses on the discovery, development, and commercialization of innovative medicines, particularly in oncology, autoimmune, and infectious diseases.

When was Zai Lab Limited founded?

Zai Lab Limited was founded in 2013 by a team of industry veterans.

What are some key products in Zai Lab's pipeline?

Key products include ZL-2306 for various solid tumors, ZL-2401, a novel antibiotic, and ZL-2301, an oral small molecule targeting hepatocellular carcinoma.

How does Zai Lab Limited approach drug development?

Zai Lab employs a dual approach of in-licensing products and internal R&D to develop a rich pipeline of promising drug candidates.

What recent achievements has Zai Lab Limited made?

Recent achievements include initiating multiple late-stage clinical trials, forming strategic partnerships, and expanding research facilities.

Who are the founders of Zai Lab Limited?

The company was founded by industry veterans known for their contributions to China's biotech industry and their successful regulatory filings.

What partnerships has Zai Lab Limited established?

Zai Lab has developed various partnership models with multinational pharmaceutical companies to enhance drug development and commercialization.

Where does Zai Lab Limited conduct clinical development?

Zai Lab conducts clinical development both in China and internationally.

Who backs Zai Lab Limited financially?

A leading group of healthcare investors provides strong financial backing to Zai Lab Limited.

What is Zai Lab Limited's vision?

Zai Lab aims to address the largest unmet medical needs and transform patients’ lives around the world.

Zai Lab Limited American Depositary Shares

Nasdaq:ZLAB

ZLAB Rankings

ZLAB Stock Data

2.84B
105.82M
1.97%
44.44%
4.96%
Biotechnology
Pharmaceutical Preparations
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United States of America
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