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XORTX Announces Appointment of Chief Technology Officer

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XORTX Therapeutics has appointed Dr. David MacDonald as the new Chief Technology Officer (CTO), enhancing its leadership with over 30 years of drug development expertise. Dr. MacDonald previously held senior roles at MSI Methylation Sciences and Active Pass Pharmaceutics, demonstrating a solid track record in R&D and clinical development. The company also issued 127,500 stock options priced at $2.54 CAD, set to expire in five years. XORTX focuses on developing therapies for progressive kidney diseases, with clinical products aimed at ADPKD and acute organ injury related to COVID-19.

Positive
  • Appointment of Dr. David MacDonald as CTO strengthens leadership with extensive experience in drug development.
  • Dr. MacDonald’s background aligns with the company's clinical and commercialization plans.
  • Issuance of stock options may incentivize employees and align interests with shareholders.
Negative
  • None.

CALGARY, Alberta, Jan. 20, 2022 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. ("XORTX" or the “Company”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a pharmaceutical therapeutics company focused on developing innovative therapies to treat progressive kidney disease, is pleased to announce the appointment of Dr. David MacDonald as Chief Technology Officer (CTO). Dr. MacDonald has an over 30-year record of achievement in drug development and leadership in pharma and biotech, achieving critical, value-inflection milestones for those companies. 

Dr. Allen Davidoff, CEO of XORTX stated, “We are delighted to welcome Dr. MacDonald to the management team and into a leadership role with the Company. David brings to team C-Suite leadership, extensive regulatory and clinical experience as well as a strong background innovating technology in drug development - qualities that align with the clinical, regulatory and commercialization plans for the future.”

Prior to XORTX, Dr. MacDonald held positions as CTO and later President of MSI Methylation Sciences Inc. a clinical-stage pharmaceutical company (“MSI”). As CTO David led R&D, pharmaceutical product and clinical development.  Prior to his position at MSI, David acted as President and CEO of Active Pass Pharmaceutics. In addition, he has held leadership positions in several small and large pharma biotech companies during which he was responsible for a broad range of technical departments and stages of development covering basic research, IND-enabling studies, formulation, CMC, clinical trials, intellectual property, and regulatory submissions and inspections. 

Dr. MacDonald is an inventor on over 20 patents issued globally and has published 14 manuscripts in peer reviewed journals.  He obtained his Ph.D. in Chemistry from the University of Alberta where his research was focused on enzymology.  https://www.linkedin.com/in/dmac36/.

In other news, the Company has issued an aggregate of 127,500 options to purchase common shares of the Company to certain officers, employees and consultants in accordance with the Company’s stock option plan. The options are exercisable at a price of $2.54 CAD per common share and expire five years from the date of grant.

About XORTX Therapeutics Inc.

XORTX Therapeutics Inc. is a pharmaceutical company with two clinically advanced products in development – XRx-008 for Autosomal Dominant Polycystic Kidney Disease (ADPKD), XRx-101 for acute kidney and other acute organ injury associated with Coronavirus / COVID-19 infection and XRx-225 is a pre-clinical stage program for Type 2 Diabetic Nephropathy (T2DN). XORTX is working to advance its clinical development stage products that target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid. At XORTX Therapeutics, we are dedicated to developing medications to improve the quality of life and future health of patients. Additional information on XORTX Therapeutics is available at www.xortx.com.

For further information, please contact:
  
Allen Davidoff, CEONick Rigopulos, Director of Communications
adavidoff@xortx.com or +1 403 455 7727 nick@alpineequityadv.com or +1 617 901 0785

The TSX Venture Exchange and Nasdaq have neither approved nor disapproved the contents of this news release. No stock exchange, securities commission or other regulatory authority has approved or disapproved the information contained herein.


FAQ

Who has been appointed as the new CTO of XORTX Therapeutics?

Dr. David MacDonald has been appointed as the new Chief Technology Officer of XORTX Therapeutics.

What is Dr. David MacDonald's experience prior to joining XORTX?

Dr. MacDonald has over 30 years of experience in drug development and leadership roles in various pharmaceutical companies.

What is the significance of Dr. MacDonald's appointment for XORTX?

His extensive regulatory and clinical experience is expected to bolster XORTX's clinical and commercialization plans.

What stock options were issued by XORTX Therapeutics?

XORTX issued 127,500 stock options to officers, employees, and consultants, exercisable at $2.54 CAD each.

What products is XORTX Therapeutics developing?

XORTX is developing therapies for Autosomal Dominant Polycystic Kidney Disease and COVID-19 related organ injuries.

XORTX Therapeutics Inc.

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Biotechnology
Healthcare
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United States of America
Alberta Beach