XORTX Therapeutics Inc. - XRTX STOCK NEWS

XORTX Therapeutics has filed a Pre-Phase 3 Meeting Briefing Package with the FDA regarding its XRx-008 program for treating autosomal dominant polycystic kidney disease (ADPKD). The virtual meeting is set for September 16, 2022. Recent R&D milestones include the manufacturing of clinical quality GMP oxypurinol and improvements in drug formulation. This progress positions XORTX favorably for key discussions with the FDA about essential clinical steps ahead of filing a New Drug Application (NDA).

XORTX Therapeutics Inc. (NASDAQ: XRTX) announced positive outcomes from its 2022 Annual and Special Meeting of Shareholders on July 20, 2022. Approximately 4.5 million shares were voted, representing 35% of outstanding shares. All proposed resolutions passed with near-unanimous support, including the election of seven directors and the re-appointment of Smythe LLP as auditors. The meeting also saw the approval of a 10% rolling stock option plan, underscoring shareholder confidence in the company's future.

XORTX Therapeutics (NASDAQ: XRTX) announced that it has submitted a request for a scientific advice review to the European Medicines Agency (EMA) regarding its XRx-008 program for autosomal dominant polycystic kidney disease (ADPKD). This submission aims to discuss the program's status and plans for a global phase 3 trial, which follows recent successful R&D activities, including increased oral bioavailability of XRx-008. The company aims to enhance the drug's approval potential, benefiting over 10 million worldwide affected by ADPKD.

XORTX Therapeutics has announced positive topline results from Part 1 of its XRX-OXY-101 Pharmacokinetics Bridging Study, demonstrating a significant increase in oral bioavailability of its proprietary oxypurinol formulations. The trial, which had no adverse events, is a precursor to a planned phase 3 registration trial focused on treating autosomal dominant polycystic kidney disease (ADPKD). Key objectives include determining the optimal formulation and dosing regimen. Part 1 confirmed improved bioavailability and established a pharmacokinetics dataset that aids in future drug development.

XORTX Therapeutics Inc. (NASDAQ: XRTX) has submitted a type B pre-Phase 3 meeting request to the FDA, anticipated in about 70 days. This request follows successful R&D activities for its XRx-008 program targeting autosomal dominant polycystic kidney disease (ADPKD). Key milestones include GMP oxypurinol manufacturing and improved drug formulation. CEO Dr. Allen Davidoff emphasized the meeting's importance for discussing the registration trial protocol and New Drug Application (NDA) for their lead product, which aims to slow renal function decline in ADPKD patients.

XORTX Therapeutics Inc. (NASDAQ: XRTX) announced a "Fireside Chat" hosted by CEO Dr. Allen Davidoff on June 22, 2022, at 11 am EST. The session will present updates on innovative therapies aimed at treating progressive kidney diseases, specifically focusing on the company's clinical products: XRx-008 for Autosomal Dominant Polycystic Kidney Disease and XRx-101 for acute kidney injury related to COVID-19. Investors can register for the event through a provided link. XORTX is committed to improving patient quality of life through targeted therapies addressing purine metabolism and uric acid production.

XORTX Therapeutics Inc. (NASDAQ: XRTX) announced its participation in the BIO International Convention 2022, from June 13-16, 2022, in San Diego. CEO Dr. Allen Davidoff will present the company's progress and future plans on June 13 at 2 PM. The event aims to enhance outreach to pharmaceutical partners, with over 30 meetings scheduled. XORTX is developing innovative therapies for progressive kidney disease, including XRx-008 for ADPKD and XRx-101 targeting COVID-19 related acute kidney injury. The company focuses on improving patient quality of life.

XORTX Therapeutics, a late-stage clinical pharmaceutical company, announced its participation in the LD Micro Invitational 2022, taking place from June 7-9, 2022. CEO Dr. Allen Davidoff will present on June 8 at 9:25 am PST, providing updates on the company's progress and future plans. XORTX focuses on innovative therapies for progressive kidney disease, with products in development addressing conditions like Autosomal Dominant Polycystic Kidney Disease (ADPKD) and COVID-19 related acute kidney injury. For more details, visit www.xortx.com.

XORTX Therapeutics Inc. has appointed Mr. Anthony Giovinazzo as Chair of the Board of Directors. With over 43 years of experience in the pharmaceutical industry, Giovinazzo aims to bolster XORTX's growth, particularly in advancing the FDA-reviewed drug for kidney diseases into a Phase 3 trial. The company is focusing on developing innovative therapies for progressive kidney disease. Concurrently, XORTX granted stock options to executives, including 150,000 options to Giovinazzo, exercisable at $1.60 over five years.