Welcome to our dedicated page for Xenon Pharmaceuticals news (Ticker: XENE), a resource for investors and traders seeking the latest updates and insights on Xenon Pharmaceuticals stock.
Xenon Pharmaceuticals Inc. (Nasdaq: XENE) is a pioneering biopharmaceutical company headquartered in Vancouver, British Columbia. Focused on neurology, Xenon leverages its proprietary discovery platform, termed 'extreme genetics', to develop innovative medications. The company’s approach involves studying families with severe phenotypes to identify single-gene defects, which offer insights into human biology and serve as potential drug targets.
Xenon’s development pipeline targets a range of neurological disorders, particularly epilepsy and depression. The flagship product, XEN1101, is a potent, selective potassium channel opener currently in various phases of clinical trials for epilepsy and major depressive disorder (MDD). Xenon has ongoing Phase 3 trials for XEN1101 in focal onset seizures (X-TOLE2, X-TOLE3) and primary generalized tonic-clonic seizures (X-ACKT). The drug has shown promising efficacy in reducing seizures and improving quality of life in long-term extension studies.
Additionally, Xenon is exploring XEN1101's potential in treating MDD, with a Phase 3 program expected to begin in 2024. Recent interim data from the X-NOVA Phase 2 trial revealed significant improvements in depression symptoms, supporting further development for this indication. Xenon’s pre-clinical work includes investigations into Nav1.1 and Nav1.7 potentiators for various neurological conditions.
Key developments include a partnership with Neurocrine Biosciences to develop XEN901 (NBI-921352) for epilepsy. Xenon's financial stability, robust clinical pipeline, and strategic collaborations position it for continued growth and innovation in neurology-focused therapeutics.
Recent Achievements:
- Strong presence at AES 2023 with multiple presentations on XEN1101
- Presented new data from the Phase 2b X-TOLE trial demonstrating significant seizure freedom rates
- Expanded open-label extension study collecting over 500 patient years of data
- Announced positive topline results from X-NOVA Phase 2 trial for MDD
- Ongoing collaboration with Icahn School of Medicine for additional MDD studies
For more updates and detailed information, visit the official website.
Xenon Pharmaceuticals Inc. (Nasdaq: XENE) announced an underwritten public offering of its common shares and pre-funded warrants to purchase common shares. The offering is part of its existing shelf registration statement, and underwriters may purchase an additional 15% of shares at the public offering price within 30 days. The offering is subject to market conditions, and completion is uncertain.
Jefferies, J.P. Morgan, SVB Securities, and Stifel are the joint book-running managers for this offering.
Xenon Pharmaceuticals (Nasdaq:XENE) announced significant efficacy results from the Phase 2b X-TOLE trial of XEN1101, showing rapid reduction in focal onset seizures within one week across all doses. The median percent reduction was 55.4% for the 25 mg dose (p<0.001), with continued effectiveness in the open-label extension (OLE) phase, exceeding 70% reduction at 3 months and 80% at 12 months. The company plans to extend the OLE from three to five years. XEN1101 has shown a favorable safety profile, aligning with other anti-seizure medications.
Xenon Pharmaceuticals announced plans to initiate the Phase 3 clinical program for XEN1101 targeting focal onset seizures in the second half of 2022. Following a successful End-of-Phase 2 meeting with the FDA, Xenon expects to submit a New Drug Application (NDA) post-completion of the X-TOLE2 trial, built on strong Phase 2b data indicating significant seizure reduction. An additional Phase 3 trial, X-ACKT, for primary generalized tonic clonic seizures is also set to begin. Approximately 360 patients will partake in pivotal trials assessing the efficacy and safety of XEN1101.
Xenon Pharmaceuticals Inc. (Nasdaq:XENE), a biopharmaceutical company specializing in neurology, will participate in one-on-one investor meetings and present at the 2022 Jefferies Healthcare Conference from June 8-10, 2022, in New York, NY. Ian Mortimer, President and CEO, will present on June 8 at 2:30 pm Eastern Time. A live webcast will be available on the company’s website, with archived recordings to follow. Xenon focuses on developing therapies for neurological disorders, particularly epilepsy.
Xenon Pharmaceuticals (Nasdaq:XENE) reported its financial results for Q1 2022, highlighting key developments in its clinical programs. The company is progressing towards an end-of-Phase 2 meeting with the FDA regarding XEN1101 for epilepsy, with Phase 3 initiation expected in H2 2022. Xenon has also initiated a Phase 2 trial for XEN1101 in major depressive disorder (MDD). Financially, the company recorded revenues of $8.8 million, up from $4.4 million YoY, but incurred a net loss of $19.7 million due to increased operational costs.
Xenon Pharmaceuticals Inc. (Nasdaq:XENE) will report its first quarter 2022 financial results on May 10, 2022, after U.S. market close. The company, focused on developing therapeutics for neurological disorders, particularly epilepsy, will host a conference call at 4:30 PM ET to discuss the results. Participants can join using the provided dial-in numbers, with international access available. The event will also be streamed live on the company's investor website. Further information about their ongoing pipeline and developments can be found online.
Xenon Pharmaceuticals (NASDAQ:XENE) has announced the initiation of the Phase 2 'X-NOVA' clinical trial to assess the efficacy and safety of XEN1101 in treating Major Depressive Disorder (MDD). The study will involve approximately 150 subjects and include placebo controls. The trial aims to evaluate the impact of XEN1101 on depressive and anhedonia symptoms over six weeks. Promising pre-clinical data and previous studies support the potential of XEN1101 as a novel treatment approach for MDD. Topline results are expected in 2023.
Xenon Pharmaceuticals, focused on neurology, announced its participation in key investor conferences. The Jefferies Biotech on the Bay Summit is scheduled for April 26-27, 2022, in Miami, FL, featuring one-on-one meetings. The Bloom Burton & Co. Healthcare Investor Conference will take place on May 2-3, 2022, in Toronto, with a presentation on May 3 at 11:30 am ET. Lastly, the RBC Capital Markets Global Healthcare Conference will occur on May 17-18, 2022, in New York, highlighted by a fireside chat on May 18 at 11:00 am ET. For further details, visit Xenon's investor page.
Xenon Pharmaceuticals Inc. (Nasdaq:XENE) has announced participation in one-on-one investor meetings and a fireside chat at the 21st Annual Needham (Virtual) Healthcare Conference on April 11, 2022. The fireside chat will occur from 10:15-10:55 am Eastern Time, featuring Ian Mortimer, President and CEO, and Sherry Aulin, CFO. Recordings of the presentation will be available post-event on their website. The company is dedicated to developing innovative therapies for neurological disorders, particularly focusing on epilepsy.
Xenon Pharmaceuticals (Nasdaq:XENE) announced participation in the Stifel 2022 CNS Days virtual conference on March 29, 2022. Management will engage in one-on-one investor meetings and a fireside chat from 11:00-11:25 am Eastern Time. Presenters include Ian Mortimer, President and CEO, and Chris Von Seggern, Chief Commercial Officer.
The company focuses on developing innovative therapeutics for neurological disorders and has a pipeline aimed at addressing high unmet medical needs, particularly in epilepsy.
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