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Exicure to Present at Upcoming Scientific Conferences

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Exicure, a biotechnology company focused on gene therapy, announced its participation in two significant scientific conferences in November 2021. At TIDES EU, Bart Anderson will present on the development of Spherical Nucleic Acids targeting SCN9A for neuropathic pain on November 16. Additionally, at Neuroscience 2021, presentations will include research on Spherical Nucleic Acids targeting frataxin in Friedreich’s ataxia and their biodistribution in mouse models. Exicure is advancing its therapeutic candidates, including XCUR-FXN for Friedreich’s ataxia and cavrotolimod for advanced solid tumors.

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CHICAGO & CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Exicure, Inc.® (NASDAQ: XCUR), a pioneer in gene regulatory and immunotherapeutic drugs utilizing spherical nucleic acid (SNA™) technology, today announced presentations at the following scientific conferences during the month of November:

TIDES EU
Title: "Development of Spherical Nucleic Acids Targeting SCN9A For the Treatment of Neuropathic Pain"
Presented by: Bart Anderson, Senior Director, R&D
Date: November 16, 2021
Time: 8:45am CET / 1:45am U.S. CST

Neuroscience 2021 (The Society for Neuroscience)
Poster 1: "Spherical Nucleic Acids Targeting FXN Induce Frataxin Expression in Models of Friedreich’s Ataxia"
Presented by: Grant Corbett, Group Lead, Neuroscience
Poster 2: "Biodistribution of Spherical Nucleic Acids in the Mouse CNS Following ICV, ICM and IT Delivery"
Presented by: Lauren Moore, Senior Scientist, Neuroscience
November 8-11, 2021

About Exicure, Inc.

Exicure, Inc. is a clinical-stage biotechnology company developing therapeutics for neurology, immuno-oncology, inflammatory diseases and other genetic disorders based on its proprietary Spherical Nucleic Acid, or SNA technology. Exicure believes that its proprietary SNA architecture has distinct chemical and biological properties that may provide advantages over other nucleic acid therapeutics and may have therapeutic potential to target diseases not typically addressed with other nucleic acid therapeutics. Exicure is in preclinical development of XCUR-FXN, a lipid-nanoparticle SNA–based therapeutic candidate, for the intrathecal treatment of Friedreich’s ataxia (FA). Exicure’s therapeutic candidate cavrotolimod (AST-008) is in a Phase 1b/2 clinical trial in patients with advanced solid tumors. Exicure is based in Chicago, IL and in Cambridge, MA. www.exicuretx.com

Media:

Karen Sharma

MacDougall

781-235-3060

ksharma@macbiocom.com

Source: Exicure, Inc.

FAQ

What is Exicure presenting at TIDES EU on November 16, 2021?

Exicure will present on the development of Spherical Nucleic Acids targeting SCN9A for neuropathic pain.

What research will Exicure showcase at Neuroscience 2021?

Exicure will present studies on Spherical Nucleic Acids targeting frataxin in Friedreich’s ataxia and their biodistribution in mouse CNS models.

What is the significance of Exicure's SNA technology?

Exicure's SNA technology may offer therapeutic advantages for conditions not effectively targeted by traditional nucleic acid therapeutics.

What are Exicure’s current drug candidates?

Exicure is developing XCUR-FXN for Friedreich’s ataxia and cavrotolimod for advanced solid tumors.

Exicure, Inc.

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