Welcome to our dedicated page for Wave Life Sciences Ltd. news (Ticker: $WVE), a resource for investors and traders seeking the latest updates and insights on Wave Life Sciences Ltd. stock.
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Wave Life Sciences presents promising data on WVE-N531 for Duchenne muscular dystrophy at the 2024 MDA Conference, showcasing potential therapeutic effects on satellite cells and muscle regeneration.
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Wave Life Sciences Ltd. (Nasdaq: WVE) announced key 2024 milestones across its clinical programs, growing pipeline, and leading RNA medicines platform. The company is well-capitalized with $142 million of cash inflows in 4Q 2023, including $115 million from December financing and $27 million in collaboration milestone payments.
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Wave Life Sciences Ltd. (Nasdaq: WVE) to present at the 42nd Annual J.P. Morgan Healthcare Conference. Paul Bolno, MD, MBA, President and CEO, to speak on January 10, 2024, at 3:00 p.m. PT / 6:00 p.m. ET. A live webcast will be available on the Investor Relations page of the company's website.
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Wave Life Sciences Ltd. (Nasdaq: WVE) has initiated dosing in the Phase 2 FORWARD-53 clinical trial, evaluating WVE-N531 as a treatment for boys with Duchenne muscular dystrophy (DMD) who are amenable to exon 53 skipping. The trial aims to assess functional dystrophin protein at 24 and 48 weeks with every other week dosing of WVE-N531. The company has demonstrated the highest level of exon skipping ever observed in the clinic and high muscle concentrations of WVE-N531 in skeletal muscle of 6.1 micromolar. The potential for monthly dosing in the future is also anticipated.
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Wave Life Sciences Ltd. (Nasdaq: WVE) announced the pricing of its underwritten public offering of 20,000,000 ordinary shares at $5.00 per share, expecting to raise approximately $100 million. The company granted underwriters a 30-day option to purchase up to an additional 3,000,000 shares. The offering is expected to close soon.
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Wave Life Sciences Ltd. (Nasdaq: WVE) has commenced an underwritten public offering of $100 million in aggregate of its ordinary shares, and pre-funded warrants to purchase ordinary shares. The offering is subject to market and other conditions, with J.P. Morgan and Leerink Partners acting as joint book-running managers. The company intends to grant the underwriters a 30-day option to purchase ordinary shares in an amount up to an additional 15% of the total amount of ordinary shares and pre-funded warrants sold in the public offering on the same terms and conditions.
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Wave Life Sciences Ltd. (Nasdaq: WVE) announced the initiation of dosing in healthy volunteers in the RestorAATion clinical trial program, investigating WVE-006 as a potential treatment for alpha-1 antitrypsin deficiency (AATD). WVE-006 is a first-in-class, GalNAc-conjugated RNA editing oligonucleotide designed to restore circulation of healthy, wild-type alpha-1 antitrypsin (M-AAT) protein and reduce dysfunctional Z-AAT protein, addressing AATD-related lung disease, liver disease, or both. Wave earned a $20 million USD milestone from GSK for initiation of dosing and is eligible for additional milestones of up to $505 million for WVE-006. Proof-of-mechanism data in individuals with AATD, as measured by restoration of M-AAT protein, is expected in 2024. Wave is also advancing a pipeline of wholly owned RNA editing therapeutics beyond WVE-006 and across a range of high-impact GalNAc-hepatic and extra hepatic targets.
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Wave Life Sciences Ltd. (WVE) CEO Paul Bolno to participate in fireside chat at Evercore ISI HealthCONx Conference on Nov. 29, 2023
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Wave Life Sciences Ltd. (Nasdaq: WVE) announced the initiation of the RestorAATion clinical program for WVE-006, the industry’s first RNA editing clinical candidate. The program is set to investigate WVE-006 as a treatment for alpha-1 antitrypsin deficiency (AATD). Additionally, the company announced progress in their WVE-N531 and WVE-003 clinical development programs and presented preclinical proof-of-concept data for a new GalNAc-siRNA program targeting INHBE for metabolic disorders, including obesity. The company also reported cash and cash equivalents of $140 million as of September 30, 2023, with a runway expected into 2025.
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Wave Life Sciences Ltd. will host a live webcast and conference call on November 9, 2023, to review their third quarter 2023 financial results and provide business updates. Analysts can join the conference call and a recorded version will be available on the company's website.
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Wave Life Sciences Ltd.
Nasdaq:WVE
WVE Rankings
WVE Stock Data
756.80M
67.25M
18.2%
74.85%
2.94%
Pharmaceutical Preparation Manufacturing
Manufacturing
United States of America
SINGAPORE
About WVE
wave life sciences ltd. (nasdaq: wve) is utilizing its innovative and proprietary synthetic chemistry drug development platform to design, develop and commercialize stereopure nucleic acid therapeutics that precisely target the underlying cause of rare genetic diseases, delivering new treatment options for patients. given the unique versatility of its chemistry platform, wave’s pipeline spans multiple oligonucleotide modalities including antisense, exon-skipping and single-stranded rnai.