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Wave Life Sciences Ltd. Ordinary Shares - WVE STOCK NEWS

Welcome to our dedicated page for Wave Life Sciences Ltd. Ordinary Shares news (Ticker: WVE), a resource for investors and traders seeking the latest updates and insights on Wave Life Sciences Ltd. Ordinary Shares stock.

Wave Life Sciences Ltd. (Nasdaq: WVE) is a clinical-stage biotechnology company harnessing its groundbreaking synthetic chemistry platform to create stereopure nucleic acid therapeutics. Focused on rare genetic diseases, Wave's pipeline addresses conditions such as alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy (DMD), and Huntington's disease. Wave's proprietary PRISMTM platform integrates various RNA modalities, including RNA editing, antisense, exon-skipping, and RNA interference, enabling scientific breakthroughs that address both rare and common disorders.

Recently, Wave has made significant progress with its Phase 2 FORWARD-53 trial for DMD, showing promising results with WVE-N531. This trial, which began dosing in December 2023, aims to evaluate dystrophin protein generation in boys amenable to exon 53 skipping, with critical data expected in 2024. The company also anticipates delivering first-of-its-kind RNA editing proof-of-mechanism data in 2024 for its WVE-006 program, targeting alpha-1 antitrypsin deficiency.

Financially, Wave is well-capitalized, with substantial cash inflows and strategic partnerships, including a notable collaboration with GSK. This partnership has led to significant milestone payments and the initiation of development programs utilizing Wave's advanced GalNAc-siRNA format.

Wave Life Sciences is at the forefront of RNA medicine, driven by a commitment to transform human health and provide life-changing treatments for devastating diseases.

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Wave Life Sciences Ltd. (Nasdaq: WVE) announced that CEO Paul Bolno and CMO Michael Panzara will participate in a virtual fireside chat at the Third Annual Stifel CNS Day on April 1, 2021, at 11:30 a.m. ET. Investors can access the presentation live via the company's investor relations page, with a replay available for 90 days afterward. Wave Life Sciences focuses on developing genetic medicines through its proprietary PRISM platform, targeting a range of genetically defined diseases.

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Wave Life Sciences (WVE) reported a $28.8 million net loss for Q4 2020, down from $56.8 million in Q4 2019. For the full year, net loss was $149.9 million, improved from $193.6 million. R&D expenses decreased to $30 million in Q4 2020 from $49.1 million in Q4 2019, driven by cost reductions. Wave plans to advance five clinical programs in 2021, including novel therapies for Huntington’s disease and ALS. The company ended 2020 with $184.5 million in cash, projected to last into Q2 2023.

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Wave Life Sciences (Nasdaq: WVE) announced a live webcast and conference call scheduled for March 4, 2021, at 8:00 a.m. ET to discuss its fourth quarter and full year 2020 financial results. The company focuses on developing innovative genetic medicines using proprietary technology aimed at treating genetically defined diseases. Investors can access the call via the company's Investor Relations page or by phone. An archived version will be available post-call.

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Wave Life Sciences (Nasdaq: WVE) announced that CEO Paul Bolno will participate in an analyst-led fireside chat at the 10th Annual SVB Leerink Global Healthcare Conference on February 25, 2021, at 5:00 p.m. ET. The event will be accessible via a live webcast on the company's investor relations page, with a replay available for 90 days post-event. Wave Life Sciences focuses on developing innovative therapies for genetically defined diseases through its proprietary PRISM platform, aiming to create effective treatments and improve patient outcomes.

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Wave Life Sciences (Nasdaq: WVE) announced key milestones for 2021, including the initiation of three clinical trials utilizing novel PN backbone chemistry. These studies will target Huntington’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, and Duchenne muscular dystrophy. Data from ongoing PRECISION-HD trials for Huntington’s disease is expected by the end of Q1 2021, aiding potential Phase 3 decision-making. Wave's proprietary PRISM platform continues to advance, with in vivo data for alpha-1 antitrypsin deficiency anticipated in the first half of 2021.

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Wave Life Sciences Ltd. (Nasdaq: WVE) has appointed Jonathan Rosin as the new Chief Human Resources Officer (CHRO). With over 25 years of HR experience, Rosin aims to enhance Wave's clinical trial support and organizational development. His prior role as CHRO at Ironwood Pharmaceuticals involved significant cultural and capability advancements. Rosin received stock options for 53,000 shares and 27,000 restricted shares as part of his compensation. This strategic leadership change intends to foster growth and maintain Wave's unique culture while advancing their drug development efforts.

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Wave Life Sciences Ltd. (Nasdaq: WVE) is set to present at the 29th Annual Credit Suisse Healthcare Conference on November 11, 2020, at 5:00 p.m. ET. Dr. Paul Bolno, President and CEO, will deliver the presentation. A live webcast can be accessed through the company's Investor Relations page, with a recording available for 60 days post-event. Wave Life Sciences focuses on developing innovative genetic treatments using its proprietary PRISM platform to design and optimize stereopure oligonucleotides, addressing various genetically defined diseases.

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Wave Life Sciences Ltd. (WVE) reported its third quarter 2020 financial results, highlighting a cash balance of $216.4 million. The company is advancing several clinical trials, including WVE-003 for Huntington's disease and WVE-004 for ALS, with clinical trial applications expected in early 2021. Wave announced its first ADAR editing program targeting alpha-1 antitrypsin deficiency. R&D expenses decreased to $28.3 million from $44.6 million in Q3 2019, while the net loss narrowed to $33.1 million. The company anticipates funding through mid-2023 after a $93.7 million capital raise.

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Wave Life Sciences (Nasdaq: WVE) will host a live webcast and conference call on November 9, 2020, at 8:30 a.m. ET to discuss its third quarter 2020 financial results and provide a business update. Investors can access the webcast via the Investor Relations section of the company’s website. Wave focuses on developing genetic medicines for severe diseases using its proprietary PRISM platform, which enables the design and production of stereopure oligonucleotides.

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Wave Life Sciences Ltd. (Nasdaq: WVE) announced that CEO Paul Bolno will present at the Chardan Virtual 4th Annual Genetic Medicines Conference on October 6, 2020, at 4:45 p.m. ET. A live webcast of the presentation will be available on the company's Investor Relations page, with a replay accessible for 90 days post-event. Wave is dedicated to developing transformative genetic medicines using its proprietary PRISM platform to target genetically defined diseases, aiming to improve patients' futures.

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FAQ

What is the current stock price of Wave Life Sciences Ltd. Ordinary Shares (WVE)?

The current stock price of Wave Life Sciences Ltd. Ordinary Shares (WVE) is $14.26 as of November 20, 2024.

What is the market cap of Wave Life Sciences Ltd. Ordinary Shares (WVE)?

The market cap of Wave Life Sciences Ltd. Ordinary Shares (WVE) is approximately 2.2B.

What is Wave Life Sciences Ltd.?

Wave Life Sciences Ltd. (Nasdaq: WVE) is a biotechnology company focused on developing stereopure nucleic acid therapeutics for genetic diseases using its proprietary PRISMTM platform.

What diseases is Wave targeting?

Wave Life Sciences is developing treatments for diseases such as alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington's disease.

What is the PRISMTM platform?

PRISMTM is Wave's proprietary platform that combines multiple RNA modalities, chemistry innovation, and genetic insights to create RNA-targeting therapies.

What is the FORWARD-53 trial?

FORWARD-53 is a Phase 2 trial evaluating WVE-N531 for boys with Duchenne muscular dystrophy amenable to exon 53 skipping. It aims to assess dystrophin protein levels and safety.

What recent achievements has Wave Life Sciences made?

Wave has initiated dosing in the FORWARD-53 trial, advanced its WVE-006 program, and received significant milestone payments through its partnership with GSK.

How is Wave Life Sciences funded?

Wave Life Sciences is well-capitalized with substantial cash inflows, including $142 million in Q4 2023 and additional payments under existing collaborations.

What is WVE-006?

WVE-006 is Wave's RNA editing candidate for alpha-1 antitrypsin deficiency, designed to restore functional M-AAT protein and expected to provide proof-of-mechanism data in 2024.

What is the significance of the partnership with GSK?

The partnership with GSK allows Wave to advance multiple RNA-targeting programs, providing substantial milestone payments and leveraging Wave's PRISMTM platform.

What is Wave's approach to RNA medicines?

Wave Life Sciences employs a multimodal approach, utilizing RNA editing, splicing, RNA interference, and antisense silencing to design precise, effective therapies.

Where is Wave Life Sciences headquartered?

Wave Life Sciences is headquartered in Cambridge, Massachusetts.

Wave Life Sciences Ltd. Ordinary Shares

Nasdaq:WVE

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2.16B
129.41M
15.04%
78.49%
4.48%
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