Welcome to our dedicated page for Windtree Therapeutics news (Ticker: WINT), a resource for investors and traders seeking the latest updates and insights on Windtree Therapeutics stock.
Windtree Therapeutics, Inc. (NASDAQ: WINT) is a pioneering biotechnology company specializing in the development of innovative therapies for critical cardiovascular and respiratory conditions. The company's advanced research and proprietary technologies aim to address significant unmet medical needs, offering hope to patients and their families.
At the core of Windtree's portfolio is its KL4 surfactant technology, a synthetic, peptide-containing surfactant structurally similar to human pulmonary surfactant. This technology is being developed for noninvasive administration via aerosolization, with a primary focus on treating Respiratory Distress Syndrome (RDS) in premature infants. The potential of this technology extends to various other respiratory diseases, promising new therapeutic avenues where few or no approved treatments exist.
In the cardiovascular domain, Windtree is advancing istaroxime, a Phase 2 candidate exhibiting unique dual mechanisms that enhance both systolic and diastolic cardiac functions. Istaroxime targets acute heart failure and cardiogenic shock, conditions with high mortality and limited treatment options. Recent collaborations, including a significant license agreement with Lee's Pharmaceutical, aim to develop and commercialize istaroxime in Greater China, reflecting its global potential.
Windtree is also exploring preclinical SERCA2a activators for heart failure, aiming to develop both intravenous and oral formulations to treat acute and chronic heart failure, respectively. Additionally, the company is advancing rostafuroxin, targeting hypertension in patients with specific genetic markers, and a preclinical atypical protein kinase C iota (aPKCi) inhibitor, for potential oncology applications.
Financially, Windtree's strategic licensing and partnerships, such as the recent agreement with Deerfield Management to retire a $15 million liability, have strengthened its balance sheet. The company is strategically positioned to advance its late-stage clinical programs while optimizing its financial resources to support ongoing and future endeavors.
Windtree's commitment to scientific innovation and strategic collaborations is poised to transform treatment paradigms in cardiovascular and respiratory care, with a robust pipeline that holds significant promise for the future.
Windtree Therapeutics announced the issuance of U.S. Patent No. 11197869, covering the intravenous delivery of istaroxime for treating acute heart failure, protecting its intellectual property until late 2039. This patent allows for longer infusion durations, enhancing outcomes related to diastolic function. Istaroxime, a dual mechanism therapy, has shown significant improvements in cardiac function and has received FDA Fast Track designation. Windtree plans to expand its intellectual property around istaroxime as it approaches crucial clinical study results in 2022.
Windtree Therapeutics is advancing its study on istaroxime for early cardiogenic shock patients, highlighting the urgent need for new treatments; inpatient mortality rates reached 30% in 2020 for this condition. The company aims to complete its phase 2 study, evaluating istaroxime's effectiveness to improve blood pressure and cardiac function without severe side effects. Results are expected in Q1 2022, aiming for regulatory discussions to expedite development.
Windtree Therapeutics, Inc. (NasdaqCM: WINT) reported its Q3 2021 financial results, highlighting ongoing clinical advancements for istaroxime as a treatment for early cardiogenic shock. The company posted an operating loss of $8.1 million, a slight improvement from $8.7 million in Q3 2020. R&D expenses increased to $4.7 million, reflecting the development of istaroxime. Windtree raised $3.2 million in October 2021, bringing cash reserves to $24.5 million, expected to sustain operations for the next year. Topline data for istaroxime is anticipated in Q1 2022.
Windtree Therapeutics (NasdaqCM: WINT) announced a Notice of Allowance for a new patent by the USPTO, which will protect the istaroxime formulation until late 2039. This patent covers longer infusion durations aimed at improving treatment outcomes for acute heart failure. Following successful Phase 2 studies showing enhanced cardiac function, Windtree plans to initiate a new study in mid-2022 targeting patients with normal to low blood pressure. The ongoing development of istaroxime continues to position Windtree for future clinical advancement.
Windtree Therapeutics (NasdaqCM: WINT) will host a Key Opinion Leader (KOL) webinar on istaroxime, targeting acute heart failure, on October 19, 2021, at 8:00 am ET. Dr. John Teerlink from UCSF will present insights on current treatments and the unmet needs in acute heart failure. The event will include discussions on istaroxime's clinical development, which includes two Phase 2 trials and a Phase 2 study in early cardiogenic shock. A live Q&A will follow. Registration for the webinar is available here.
Windtree Therapeutics (NasdaqCM: WINT) announced that Craig Fraser, CEO, will present at the Oppenheimer Fall Healthcare Life Sciences and MedTech Summit on September 22, 2021, at 9:55 am ET. The live webcast will be accessible via the company's Investor Events page. Windtree focuses on late-stage interventions for acute cardiovascular and pulmonary disorders, with its lead candidate, istaroxime, aimed at treating acute heart failure. They also develop AEROSURF® for respiratory distress in infants and are exploring treatments for COVID-19-related respiratory issues.
Windtree Therapeutics (WINT) reported second-quarter results for 2021, highlighting ongoing clinical trials for istaroxime and lucinactant, targeting cardiogenic shock and COVID-19 lung injury respectively. The operating loss reached $45.4 million, largely due to a $37.8 million impairment on rostafuroxin assets. R&D expenses decreased to $4.2 million, and general administrative costs were stable at $3.4 million. A net loss of $37.4 million ($1.42 per share) was recorded. The company maintains a cash position of $30 million, expected to support operations for at least the next year.
Windtree Therapeutics (NasdaqCM: WINT) has appointed Randall White, Ph.D., as Vice President of Clinical Program Management. Dr. White brings over 20 years of pharmaceutical research experience, previously serving at Daiichi Sankyo and Bristol-Myers Squibb. His expertise will support Windtree's clinical development projects. To incentivize his employment, the company granted Dr. White a stock option for 100,000 shares at the closing price on the grant date. Windtree focuses on interventions for acute cardiovascular and pulmonary disorders, with key products including istaroxime and AEROSURF®.
Windtree Therapeutics, focused on acute cardiovascular and pulmonary therapies, announced CEO Craig Fraser's upcoming presentation at the Access to Giving Virtual Investor conference from July 13-15, 2021. Windtree is scheduled to present on July 15, 2021, at 10:00 AM ET. The conference will feature over 50 companies and aims to promote investor education and advocacy, with funds raised directed to financial literacy initiatives. The presentation will be available for replay on the company’s website, and one-on-one meetings can be arranged with management.
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