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GeneDx Reports Second Quarter 2024 Financial Results and Business Highlights

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GeneDx (Nasdaq: WGS) reported strong Q2 2024 financial results, with revenue from continuing operations reaching $68.9 million, a 52% year-over-year increase. Exome and genome test revenue grew 77% to $50.7 million. Adjusted gross margin expanded to 62%, while adjusted net loss narrowed to $2.7 million. The company raised its full-year 2024 revenue guidance to $255-$265 million and reiterated its expectation to reach profitability in 2025.

Key highlights include a 52% year-over-year increase in exome and genome test volume, expanded Medicaid coverage for whole exome sequencing, and new collaborations to enhance access to rapid whole genome sequencing. GeneDx also announced reinvestment in whole genome sequencing products, improving turnaround times and sample collection methods.

GeneDx (Nasdaq: WGS) ha riportato risultati finanziari solidi per il secondo trimestre del 2024, con entrate dalle operazioni continuative che hanno raggiunto 68,9 milioni di dollari, registrando un incremento del 52% rispetto all'anno precedente. Le entrate dai test di esoma e genoma sono cresciute del 77% a 50,7 milioni di dollari. Il margine lordo rettificato è aumentato al 62%, mentre la perdita netta rettificata si è ridotta a 2,7 milioni di dollari. L'azienda ha alzato le previsioni di ricavi per l'intero anno 2024 a 255-265 milioni di dollari e ha ribadito la sua aspettativa di raggiungere la redditività nel 2025.

Tra i principali punti salienti si segnalano un incremento del 52% nel volume dei test di esoma e genoma rispetto all'anno precedente, l'espansione della copertura Medicaid per il sequenziamento dell'intero esoma e nuove collaborazioni per migliorare l'accesso al sequenziamento rapido dell'intero genoma. GeneDx ha anche annunciato un reinvestimento nei prodotti per il sequenziamento dell'intero genoma, migliorando i tempi di risposta e i metodi di raccolta dei campioni.

GeneDx (Nasdaq: WGS) reportó resultados financieros sólidos para el segundo trimestre de 2024, con ingresos de operaciones continuas alcanzando $68.9 millones, un aumento del 52% en comparación con el año anterior. Los ingresos de pruebas de exoma y genoma crecieron un 77% hasta $50.7 millones. El margen bruto ajustado se amplió al 62%, mientras que la pérdida neta ajustada se redujo a $2.7 millones. La compañía elevó su guía de ingresos para todo el año 2024 a $255-$265 millones y reiteró su expectativa de alcanzar la rentabilidad en 2025.

Los puntos clave incluyen un aumento del 52% en el volumen de pruebas de exoma y genoma en comparación con el año anterior, la expansión de la cobertura de Medicaid para el secuenciación del exoma completo y nuevas colaboraciones para mejorar el acceso a la secuenciación rápida del genoma completo. GeneDx también anunció la reinversión en productos de secuenciación del genoma completo, mejorando los tiempos de respuesta y los métodos de recolección de muestras.

GeneDx (Nasdaq: WGS)는 2024년 2분기 재무 실적이 강력하다고 보고했습니다. 지속적인 운영에서의 수익은 6,890만 달러에 달하며, 이는 지난해 대비 52% 증가한 수치입니다. 엑솜 및 유전체 검사 수익은 77% 증가하여 5,070만 달러에 도달했습니다. 조정된 총 마진은 62%로 확대되었으며, 조정된 순손실은 270만 달러로 축소되었습니다. 회사는 2024년 전체 연간 수익 전망을 2억 5천 5백만 - 2억 6천 5백만 달러로 상향 조정하며, 2025년에는 수익성이 달성될 것으로 예상된다고 다시 확인했습니다.

주요 하이라이트로는 엑솜 및 유전체 검사량이 지난해 대비 52% 증가한 것, 전체 엑솜 시퀀싱에 대한 메디케이드 보장 확대, 신속한 전체 유전체 시퀀싱에 대한 접근성을 높이기 위한 새로운 협력 등이 있습니다. GeneDx는 또한 전체 유전체 시퀀싱 제품에 대한 재투자를 발표하며, 응답 시간과 샘플 수집 방법을 개선하였습니다.

GeneDx (Nasdaq: WGS) a annoncé de solides résultats financiers pour le deuxième trimestre 2024, avec des revenus d'opérations continues atteignant 68,9 millions de dollars, soit une augmentation de 52 % par rapport à l'année précédente. Les revenus des tests d'exome et de génome ont augmenté de 77 % pour atteindre 50,7 millions de dollars. La marge brute ajustée s'est élargie à 62%, tandis que la perte nette ajustée s'est réduite à 2,7 millions de dollars. L'entreprise a relevé ses prévisions de revenus pour l'ensemble de l'année 2024 à 255-265 millions de dollars et a réitéré son attente d'atteindre la rentabilité en 2025.

Les principaux points saillants incluent une augmentation de 52 % du volume des tests d'exome et de génome par rapport à l'année précédente, une extension de la couverture Medicaid pour le séquençage de l'exome complet et de nouvelles collaborations pour améliorer l'accès au séquençage rapide du génome entier. GeneDx a également annoncé un réinvestissement dans les produits de séquençage de l'ensemble du génome, visant à améliorer les délais de réponse et les méthodes de collecte des échantillons.

GeneDx (Nasdaq: WGS) berichtete über starke Finanzzahlen im zweiten Quartal 2024, mit einem Umsatz aus fortgeführten Betrieben von 68,9 Millionen Dollar, was einem Anstieg von 52 % im Vergleich zum Vorjahr entspricht. Die Einnahmen aus Exom- und Genomtests wuchsen um 77 % auf 50,7 Millionen Dollar. Die bereinigte Bruttomarge erweiterte sich auf 62%, während der bereinigte Nettoverlust auf 2,7 Millionen Dollar gesenkt wurde. Das Unternehmen hob seine Umsatzprognose für das Gesamtjahr 2024 auf 255-265 Millionen Dollar und bestätigte seine Erwartung, 2025 profitabel zu werden.

Zu den wichtigsten Highlights gehören ein Anstieg des Volumens bei Exom- und Genomtests um 52 % im Jahresvergleich, eine erweiterte Medicaid-Abdeckung für die vollständige Exom-Sequenzierung und neue Kooperationen zur Verbesserung des Zugangs zur schnellen vollständigen Genomsequenzierung. GeneDx kündigte außerdem eine Reinvestition in Produkte zur vollständigen Genomsequenzierung an, um die Bearbeitungszeiten und die Probenahmemethoden zu verbessern.

Positive
  • Revenue from continuing operations grew 52% year-over-year to $68.9 million
  • Exome and genome test revenue increased 77% year-over-year to $50.7 million
  • Adjusted gross margin expanded to 62%, up from 37% in Q2 2023
  • Adjusted net loss narrowed by 93% year-over-year to $2.7 million
  • Raised full-year 2024 revenue guidance to $255-$265 million
  • Exome and genome test volume grew 52% year-over-year
  • Expanded Medicaid coverage for whole exome sequencing in multiple states
  • Launched Patient Access Program to expand access to exome testing for pediatric epilepsy patients
  • Grew biopharma partner programs to 32
Negative
  • GAAP net loss of $29.2 million, including a one-time net litigation charge of $13 million
  • Total net use of cash was $6.1 million in Q2 2024

GeneDx's Q2 2024 results demonstrate impressive growth and improved financial performance. The company reported $68.9 million in revenue from continuing operations, marking a substantial 52% year-over-year increase. Notably, exome and genome test revenue surged by 77% year-over-year to $50.7 million, indicating strong market demand for these advanced genetic tests.

The company's focus on operational efficiency is evident in its expanded adjusted gross margins, which reached 62% in Q2 2024, up from 37% in the same quarter last year. This significant margin improvement, coupled with a 24% year-over-year reduction in adjusted operating expenses, has led to a narrowed adjusted net loss of $2.7 million - a 93% improvement from the previous year.

GeneDx's cash burn has also improved dramatically, with total net use of cash at $6.1 million in Q2 2024, an 89% year-over-year improvement. The company maintains a solid cash position of $107.8 million, providing runway for future growth initiatives.

Based on these strong results, GeneDx has raised its full-year 2024 revenue guidance to $255-$265 million, up from the previous $235-$245 million range. The company also reaffirmed its expectation to reach profitability in 2025, which is a critical milestone for investors.

While the overall picture is positive, it's important to note the $13 million one-time net litigation charge, which contributed to a GAAP net loss of $29.2 million. Investors should monitor any potential future legal liabilities.

GeneDx's Q2 2024 results highlight the growing adoption of advanced genetic testing in clinical settings. The 52% year-over-year increase in exome and genome test volume, reaching 18,017 tests, underscores the increasing integration of these technologies into patient care. This trend is particularly evident in the rising proportion of exome and genome tests, now representing 31% of all test results, up from 22% in Q2 2023.

The company's strategic focus on whole exome sequencing (WES) and whole genome sequencing (WGS) is well-aligned with the evolving landscape of precision medicine. The launch of the Patient Access Program for pediatric epilepsy patients and the expansion of rapid whole genome sequencing (rWGS) services through the Epic Aura collaboration demonstrate GeneDx's commitment to broadening access to critical genetic information.

Notably, the increased Medicaid coverage for WES and rWGS in several states, including North Carolina, Tennessee and Connecticut, signals growing recognition of the clinical utility of these tests. This expanded coverage is likely to drive further adoption and could contribute to sustained revenue growth for GeneDx.

The company's investment in improving its WGS offerings, including faster turnaround times and non-invasive sample collection methods, addresses key barriers to adoption and could further accelerate market penetration. The expansion of repeat expansions covered by WGS is particularly significant, as it has the potential to increase diagnostic yield and streamline the testing process for patients and providers.

GeneDx's Q2 2024 results and strategic initiatives reveal a company well-positioned in the rapidly growing genetic testing market. The 77% year-over-year growth in exome and genome test revenue suggests strong market demand and effective commercialization strategies. This growth outpaces the overall revenue increase, indicating a shift towards higher-value genetic tests.

The company's collaboration with Epic Aura is a strategic move to expand its footprint in health systems, potentially leading to increased test volumes and market share. Similarly, the Patient Access Program for pediatric epilepsy patients demonstrates GeneDx's commitment to market expansion and patient engagement.

The growth in biopharma partner programs to 32, primarily with biotech companies seeking specific variants for clinical trials, highlights GeneDx's role in the broader pharmaceutical research ecosystem. This diversification of revenue streams could provide stability and growth opportunities beyond clinical diagnostics.

Expanded Medicaid coverage for whole exome sequencing (WES) and rapid whole genome sequencing (rWGS) in multiple states is a positive market signal, potentially leading to increased test volumes and revenue. This trend suggests growing recognition of the value of advanced genetic testing in healthcare systems.

GeneDx's investments in improving its whole genome sequencing offerings, including faster turnaround times and non-invasive sample collection, address key market needs and could enhance its competitive position. These improvements, coupled with the expansion of repeat expansions covered, could drive market share gains and customer loyalty.

The raised revenue guidance for 2024 and the reiterated path to profitability in 2025 suggest management's confidence in the company's market position and growth trajectory. However, investors should monitor competitive pressures and potential market saturation in the rapidly evolving genetic testing landscape.

Reported second quarter 2024 revenue from continuing operations1 of $68.9M with 77% year-over-year growth of exome and genome test revenue

Expanded second quarter 2024 adjusted gross margins2 from continuing operations to 62%

Narrowed second quarter 2024 adjusted net loss2 to $2.7M

Raising guidance to deliver between $255M and $265M in FY 2024 revenue and reiterate path to profitability in 2025

GeneDx to host conference call today at 4:30 p.m. ET

STAMFORD, Conn.--(BUSINESS WIRE)-- GeneDx Holdings Corp. (Nasdaq: WGS), a leader in delivering improved health outcomes through genomic insights, today reported its financial results for the second quarter of 2024.

“Our continued organizational focus on execution fueled our strong second quarter results, giving us confidence to raise full year 2024 revenue guidance to between $255-$265 million and reiterate our expectation to reach profitability in the next several quarters,” said Katherine Stueland, President and Chief Executive Officer at GeneDx. “The strength in our performance across all measures of the business has enabled us to begin investments in future growth opportunities for our business with a focus on extending our leadership in whole exome sequencing to whole genome sequencing to ensure we continue to lead the charge in quickly providing the most accurate and actionable genetic information to diagnose disease for as many patients and families as possible.”

Second Quarter 2024 Financial Results (Unaudited)1,2

Revenues

  • Revenues from continuing operations grew to $68.9 million, an increase of 52% year-over-year and 12% sequentially.
    • Total company revenues were $70.5 million.
  • Exome and genome test revenue grew to $50.7 million, an increase of 77% year-over-year and 15% sequentially.

Exome and genome volume

  • Exome and genome test results volume grew to 18,017, an increase of 52% year-over-year and 9% sequentially.
  • Exome and genome represented 31% of all test results, up from 22% in the second quarter of 2023 and up from 30% in the first quarter of 2024.

Gross margin

  • Adjusted gross margin from continuing operations expanded to 62%, up from 37% in the second quarter of 2023 and up from 61% in the first quarter of 2024.
    • Total company gross margin was 61%.

Operating expenses

  • Adjusted total operating expenses reduced to $45.0 million, a decrease of 24% year-over-year and 1% sequentially.
    • Total GAAP operating expenses were $52.7 million.

Net loss

  • Adjusted net loss narrowed to $2.7 million, an improvement of 93% year-over-year and 68% sequentially.
    • GAAP net loss was $29.2 million, inclusive of a one-time, net litigation charge of $13 million.

Cash burn and cash position

  • Total net use of cash was $6.1 million in the second quarter of 2024, an improvement of 89% year-over-year and 65% sequentially.
  • Cash, cash equivalents, marketable securities and restricted cash was $107.8 million as of June 30, 2024.
1.

Revenue and gross margin results from continuing operations, which we believe are representative of our ongoing business strategy exclude any revenue and cost of goods sold of the exited Legacy Sema4 diagnostic testing business for the current and all comparative periods. Total company results include GeneDx’s continuing operations and the financial impacts of exited Legacy Sema4 business activities for the current and all comparative periods.

2.

Adjusted gross margin, adjusted total operating expenses and adjusted net loss are non-GAAP financial measures. See appendix for a reconciliation of GAAP to Non-GAAP figures presented.

GeneDx Full Year 2024 Guidance

GeneDx has updated full year 2024 guidance. Management expects GeneDx to:

  • Drive full year 2024 revenues1 between $255 and $265 million (previous guidance was between $235 and $245 million);
  • Expand full year 2024 adjusted gross margin profile to at least 60% (no change);
  • Use between $65 to $70 million of net cash for full year 2024 (previous guidance was between $70 to $80 million);
  • Turn to profitability in 2025 (no change).
1.

Total company results include the combination of the GeneDx diagnostic business revenues and the data and information revenues from the Legacy Sema4 business.

Second Quarter 2024 Business Highlights

Driving sustainable growth, expanding access and improving the standard of care

  • Announced collaboration with Epic Aura1 to expand access to rapid whole genome sequencing (“rWGS”) services to inform diagnosis for affected pediatric and neonatal patients, enhancing GeneDx’s commercial footprint within leading health systems.
  • Launched first-of-its-kind Patient Access Program in collaboration with leading biopharma partners to expand access to exome testing for pediatric epilepsy patients.
  • Grew biopharma partner programs to 32, predominantly with biotech companies who are relying on us to find patients with a specific variant for clinical trial purposes.
  • North Carolina Medicaid has expanded its existing coverage of outpatient whole exome sequencing (“WES”) to include the analysis of family comparator samples, which increases the rate of diagnosis of WES, effective June 1, 2024.
  • State Medicaid programs continue to expand coverage of rapid genome sequencing in the neonatal intensive care unit (“NICU”), bringing total states covering rapid whole genome in the acute care setting to 14, including new coverage announced in:
    • North Carolina (June 2024)
    • Tennessee (July 2024)
    • Connecticut (July 2024)
  • Announced reinvestment in rapid and standard whole genome sequencing products, enabling:
    • Faster turnaround time for rWGS with a written report in as fast as 5 days
    • Buccal samples (cheek swab) allowing for easier and more accessible non-invasive sample collection method for even the youngest patients
    • Expanding the number of repeat expansions covered by whole genome sequencing to increase diagnostic yield and improve the provider and patient experience by decreasing the need for follow-up testing
1.

Epic and Aura are trademarks of Epic Systems Corporation.

Webcast and Conference Call Details

GeneDx will host a conference call today, July 30, 2024, at 4:30 p.m. Eastern Time. Investors interested in listening to the conference call are required to register online. A live and archived webcast of the event will be available on the “Events” section of the GeneDx investor relations website at https://ir.genedx.com/.

Forward-Looking Statements

This press release contains certain forward-looking statements within the meaning of the federal securities laws, including statements regarding our future performance and our market opportunity, including our expected full year 2024 reported revenue guidance, our expectations regarding our adjusted gross margin profile in 2024, our use of net cash in 2024 and our turning profitable in 2025. These forward-looking statements generally are identified by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will likely result,” and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this press release, including but not limited to: (i) our ability to implement business plans, goals and forecasts, and identify and realize additional opportunities, (ii) the risk of downturns and a changing regulatory landscape in the highly competitive healthcare industry, (iii) the size and growth of the market in which we operate, (iv) our ability to pursue our new strategic direction, and (v) our ability to enhance our artificial intelligence tools that we use in our clinical interpretation platform. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of our Annual Report on Form 10-K for the fiscal year ended December 31, 2023, filed with the U.S. Securities and Exchange Commission (the “SEC”) on February 23, 2024 and other documents filed by us from time to time with the SEC. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and we assume no obligation and do not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. We do not give any assurance that we will achieve our expectations.

About GeneDx

At GeneDx (Nasdaq: WGS), we believe that everyone deserves personalized, targeted medical care—and that it all begins with a genetic diagnosis. Fueled by one of the world’s largest rare disease data sets, our industry-leading exome and genome tests translate complex genomic data into clinical answers that unlock personalized health plans, accelerate drug discovery, and improve health system efficiencies. It all starts with a single test. For more information, please visit genedx.com and connect with us on LinkedIn, X, Facebook, and Instagram.

Volume and revenue in the table below include the combination of the Legacy GeneDx diagnostic business with the data and information business of Legacy Sema4.

Volume & Revenue

 

2Q24

 

1Q24

 

4Q23

 

3Q23

 

2Q23

Volumes

 

 

 

 

 

 

 

 

 

Whole exome, whole genome

 

18,017

 

 

16,592

 

 

15,663

 

 

13,216

 

 

11,855

Hereditary cancer

 

5,482

 

 

6,868

 

 

8,240

 

 

8,556

 

 

7,142

Other panels

 

34,204

 

 

31,763

 

 

33,692

 

 

35,861

 

 

35,931

Total

 

57,703

 

 

55,223

 

 

57,595

 

 

57,633

 

 

54,928

 

 

 

 

 

 

 

 

 

 

Revenue ($ millions)

 

 

 

 

 

 

 

 

 

Whole exome, whole genome

$

50.7

 

$

44.0

 

$

39.2

 

$

34.0

 

$

28.7

Hereditary cancer

 

3.8

 

 

5.5

 

 

5.5

 

 

4.5

 

 

3.8

Other panels

 

13.3

 

 

10.7

 

 

11.2

 

 

10.6

 

 

10.6

Data information

 

1.1

 

 

1.3

 

 

2.2

 

 

1.3

 

 

2.1

Total

$

68.9

 

$

61.5

 

$

58.1

 

$

50.4

 

$

45.2

Unaudited Select Financial Information (in thousands)

 

Three months ended June 30, 2024

 

Three months ended March 31, 2024

 

GeneDx

 

Legacy Sema4

 

Total

 

GeneDx

 

Legacy Sema4

 

Total

Revenue

$68,924

 

$1,590

 

$70,514

 

$61,461

 

$961

 

$62,422

Adjusted cost of services

26,523

 

145

 

26,668

 

24,099

 

 

24,099

Adjusted gross profit (loss)

$42,401

 

$1,445

 

$43,846

 

$37,362

 

$961

 

$38,323

Adjusted gross margin %

61.5%

 

90.9%

 

62.2%

 

60.8%

 

100.0%

 

61.4%

 

Three months ended June 30, 2023

 

GeneDx

 

Legacy Sema4

 

Total

Revenue

$45,226

 

$3,480

 

$48,706

Adjusted cost of services

28,452

 

 

28,452

Adjusted gross profit (loss)

$16,774

 

$3,480

 

$20,254

Adjusted gross margin %

37.1%

 

100.0%

 

41.6%

 

Three months ended June 30, 2024

 

Reported

 

Depreciation and amortization

 

Stock-based compensation expense

 

Restructuring costs

 

Change in FV of financial liabilities

 

Charges related to business exit

 

Other

 

Adjusted

Diagnostic test revenue

$

69,439

 

 

$

 

 

$

 

 

$

 

 

$

 

$

 

$

 

$

69,439

 

Other revenue

 

1,075

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,075

 

Total revenue

 

70,514

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

70,514

 

Cost of services

 

27,562

 

 

 

(808

)

 

 

(86

)

 

 

 

 

 

 

 

 

 

 

 

26,668

 

Gross profit (loss)

 

42,952

 

 

 

808

 

 

 

86

 

 

 

 

 

 

 

 

 

 

 

 

43,846

 

Gross margin

 

60.9

%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

62.2

%

Research and development

 

10,902

 

 

 

(211

)

 

 

(347

)

 

 

(35

)

 

 

 

 

 

 

 

 

10,309

 

Selling and marketing

 

16,585

 

 

 

(1,225

)

 

 

(368

)

 

 

(63

)

 

 

 

 

 

 

 

 

14,929

 

General and administrative

 

25,170

 

 

 

(2,974

)

 

 

(2,307

)

 

 

(150

)

 

 

 

 

 

 

 

 

19,739

 

Impairment loss

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other, net

 

874

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

874

 

Loss from operations

 

(10,579

)

 

 

5,218

 

 

 

3,108

 

 

 

248

 

 

 

 

 

 

 

 

 

(2,005

)

Interest income (expense), net

 

(894

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(894

)

Other income (expense), net

 

(17,890

)

 

 

 

 

 

 

 

 

 

 

 

4,409

 

 

 

 

13,450

 

 

(31

)

Income tax benefit

 

190

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

190

 

Net loss

$

(29,173

)

 

$

5,218

 

 

$

3,108

 

 

$

248

 

 

$

4,409

 

$

 

$

13,450

 

$

(2,740

)

 

Three months ended June 30, 2023

 

Reported

 

Depreciation and amortization

 

Stock-based compensation expense

 

Restructuring costs

 

Change in FV of financial liabilities

 

Charges related to business exit

 

Other

 

Adjusted

Diagnostic test revenue

$

46,635

 

 

$

 

 

$

 

 

$

 

 

$

 

 

$

 

 

$

 

 

$

46,635

 

Other revenue

 

2,071

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2,071

 

Total revenue

 

48,706

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

48,706

 

Cost of services

 

29,949

 

 

 

(1,233

)

 

 

(251

)

 

 

(13

)

 

 

 

 

 

 

 

 

 

 

 

28,452

 

Gross profit (loss)

 

18,757

 

 

 

1,233

 

 

 

251

 

 

 

13

 

 

 

 

 

 

 

 

 

 

 

 

20,254

 

Gross margin

 

38.5

%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

41.6

%

Research and development

 

17,138

 

 

 

(4,656

)

 

 

675

 

 

 

(815

)

 

 

 

 

 

 

 

 

 

 

 

12,342

 

Selling and marketing

 

15,182

 

 

 

(1,225

)

 

 

143

 

 

 

(326

)

 

 

 

 

 

 

 

 

 

 

 

13,774

 

General and administrative

 

37,341

 

 

 

(3,218

)

 

 

(675

)

 

 

(483

)

 

 

 

 

 

 

 

 

 

 

 

32,965

 

Impairment loss

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other, net

 

718

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

334

 

 

 

3,238

 

 

 

4,290

 

Loss from operations

 

(51,622

)

 

 

10,332

 

 

 

108

 

 

 

1,637

 

 

 

 

 

 

(334

)

 

 

(3,238

)

 

 

(43,117

)

Interest income (expense), net

 

1,074

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,074

 

Other income (expense), net

 

3,633

 

 

 

 

 

 

 

 

 

 

 

 

(3,547

)

 

 

 

 

 

(86

)

 

 

 

Income tax benefit

 

196

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

196

 

Net loss

$

(46,719

)

 

$

10,332

 

 

$

108

 

 

$

1,637

 

 

$

(3,547

)

 

$

(334

)

 

$

(3,324

)

 

$

(41,847

)

 

Three months ended March 31, 2024

 

Reported

 

Depreciation and amortization

 

Stock-based compensation expense

 

Restructuring costs

 

Change in FV of financial liabilities

 

Charges related to business exit

 

Other

 

Adjusted

Diagnostic test revenue

$

61,104

 

 

$

 

 

$

 

 

$

 

 

$

 

$

 

$

 

$

61,104

 

Other revenue

 

1,318

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,318

 

Total revenue

 

62,422

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

62,422

 

Cost of services

 

25,011

 

 

 

(816

)

 

 

(48

)

 

 

(48

)

 

 

 

 

 

 

 

 

24,099

 

Gross profit (loss)

 

37,411

 

 

 

816

 

 

 

48

 

 

 

48

 

 

 

 

 

 

 

 

 

38,323

 

Gross margin

 

59.9

%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

61.4

%

Research and development

 

11,567

 

 

 

(196

)

 

 

187

 

 

 

(103

)

 

 

 

 

 

 

 

 

11,455

 

Selling and marketing

 

16,085

 

 

 

(1,225

)

 

 

20

 

 

 

(400

)

 

 

 

 

 

 

 

 

14,480

 

General and administrative

 

22,445

 

 

 

(3,011

)

 

 

292

 

 

 

(292

)

 

 

 

 

 

 

 

 

19,434

 

Impairment loss

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other, net

 

974

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

974

 

Loss from operations

 

(13,660

)

 

 

5,248

 

 

 

(451

)

 

 

843

 

 

 

 

 

 

 

 

 

(8,020

)

Interest income (expense), net

 

(597

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(597

)

Other income (expense), net

 

(6,064

)

 

 

 

 

 

 

 

 

 

 

 

6,101

 

 

 

 

 

 

37

 

Income tax benefit

 

82

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

82

 

Net loss

$

(20,239

)

 

$

5,248

 

 

$

(451

)

 

$

843

 

 

$

6,101

 

$

 

$

 

$

(8,498

)

GeneDx Holdings Corp.

Condensed Consolidated Balance Sheets

(in thousands, except share and per share amounts)

 

 

June 30, 2024 (Unaudited)

 

December 31, 2023

Assets:

 

 

 

Current assets:

 

 

 

Cash and cash equivalents

$

56,076

 

 

$

99,681

 

Marketable securities

 

50,784

 

 

 

30,467

 

Accounts receivable

 

25,500

 

 

 

32,371

 

Due from related parties

 

693

 

 

 

445

 

Inventory, net

 

10,322

 

 

 

8,777

 

Prepaid expenses and other current assets

 

18,792

 

 

 

10,598

 

Total current assets

 

162,167

 

 

 

182,339

 

Operating lease right-of-use assets

 

25,624

 

 

 

26,900

 

Property and equipment, net

 

31,339

 

 

 

32,479

 

Intangible assets, net

 

165,613

 

 

 

172,625

 

Other assets (1)

 

4,357

 

 

 

4,413

 

Total assets

$

389,100

 

 

$

418,756

 

Liabilities and Stockholders’ Equity:

 

 

 

Current liabilities:

 

 

 

Accounts payable and accrued expenses

$

51,959

 

 

$

37,456

 

Due to related parties

 

1,213

 

 

 

1,379

 

Short-term lease liabilities

 

4,001

 

 

 

3,647

 

Other current liabilities

 

11,097

 

 

 

16,336

 

Total current liabilities

 

68,270

 

 

 

58,818

 

Long-term debt, net of current portion

 

52,160

 

 

 

52,688

 

Long-term lease liabilities

 

60,800

 

 

 

62,938

 

Other liabilities

 

12,660

 

 

 

14,735

 

Deferred taxes

 

1,167

 

 

 

1,560

 

Total liabilities

 

195,057

 

 

 

190,739

 

Stockholders’ Equity:

 

 

 

Preferred stock

 

 

 

 

 

Class A common stock

 

2

 

 

 

2

 

Additional paid-in capital

 

1,543,182

 

 

 

1,527,778

 

Accumulated deficit

 

(1,349,600

)

 

 

(1,300,188

)

Accumulated other comprehensive income

 

459

 

 

 

425

 

Total stockholders’ equity

 

194,043

 

 

 

228,017

 

Total liabilities and stockholders’ equity

$

389,100

 

 

$

418,756

 

(1)

Other assets includes $987 thousand of restricted cash as of both June 30, 2024 and December 31, 2023.

GeneDx Holdings Corp.

Condensed Consolidated Statements of Operations (Unaudited)

(in thousands, except share and per share amounts)

 

 

June 30,

 

Six months ended June 30,

 

2024

 

2023

 

2024

 

2023

Revenue

 

 

 

 

 

 

 

Diagnostic test revenue

$

69,439

 

 

$

46,635

 

 

$

130,543

 

 

$

88,485

 

Other revenue

 

1,075

 

 

 

2,071

 

 

 

2,393

 

 

 

3,360

 

Total revenue

 

70,514

 

 

 

48,706

 

 

 

132,936

 

 

 

91,845

 

Cost of services

 

27,562

 

 

 

29,949

 

 

 

52,573

 

 

 

57,852

 

Gross profit

 

42,952

 

 

 

18,757

 

 

 

80,363

 

 

 

33,993

 

Research and development

 

10,902

 

 

 

17,138

 

 

 

22,469

 

 

 

31,730

 

Selling and marketing

 

16,585

 

 

 

15,182

 

 

 

32,670

 

 

 

28,634

 

General and administrative

 

25,170

 

 

 

37,341

 

 

 

47,615

 

 

 

81,030

 

Impairment loss

 

 

 

 

 

 

 

 

 

 

2,120

 

Other operating expenses, net

 

874

 

 

 

718

 

 

 

1,848

 

 

 

2,465

 

Loss from operations

 

(10,579

)

 

 

(51,622

)

 

 

(24,239

)

 

 

(111,986

)

 

 

 

 

 

 

 

 

Non-operating income (expenses), net

 

 

 

 

 

 

 

Change in fair value of warrants and earn-out contingent liabilities

 

(4,409

)

 

 

3,547

 

 

 

(10,510

)

 

 

94

 

Interest expense, net

 

(894

)

 

 

1,074

 

 

 

(1,491

)

 

 

1,039

 

Other expense, net

 

(13,481

)

 

 

86

 

 

 

(13,444

)

 

 

2,802

 

Total non-operating income, net

 

(18,784

)

 

 

4,707

 

 

 

(25,445

)

 

 

3,935

 

Loss before income taxes

 

(29,363

)

 

 

(46,915

)

 

$

(49,684

)

 

$

(108,051

)

Income tax benefit

 

190

 

 

 

196

 

 

 

272

 

 

 

343

 

Net loss

$

(29,173

)

 

$

(46,719

)

 

$

(49,412

)

 

$

(107,708

)

 

 

 

 

 

 

 

 

Weighted average shares outstanding of Class A common stock

 

26,617,955

 

 

 

25,418,358

 

 

 

26,340,063

 

 

 

22,754,948

 

Basic and diluted net loss per share, Class A common stock

$

(1.10

)

 

$

(1.84

)

 

$

(1.88

)

 

$

(4.73

)

GeneDx Holdings Corp.

Condensed Consolidated Statements of Cash Flows (Unaudited)

(in thousands)

 

 

Six months ended June 30,

 

2024

 

2023

Operating activities

 

 

 

Net loss

$

(49,412

)

 

$

(107,708

)

Adjustments to reconcile net loss to net cash used in operating activities:

 

 

 

Depreciation and amortization expense

 

10,466

 

 

 

18,968

 

Stock-based compensation expense

 

2,657

 

 

 

156

 

Change in fair value of warrants and contingent liabilities

 

10,510

 

 

 

(94

)

Deferred tax benefit

 

(272

)

 

 

(343

)

Provision for excess and obsolete inventory

 

109

 

 

 

2,620

 

Legal reserves

 

13,450

 

 

 

 

Change in third party payor reserves

 

1,066

 

 

 

(4,308

)

Gain on sale of assets

 

 

 

 

(2,954

)

Gain on debt forgiveness

 

 

 

 

(2,750

)

Impairment loss

 

 

 

 

2,120

 

Other

 

1,738

 

 

 

412

 

Change in operating assets and liabilities:

 

 

 

Accounts receivable

 

6,871

 

 

 

10,174

 

Inventory

 

(1,654

)

 

 

(486

)

Accounts payable and accrued expenses

 

(10,359

)

 

 

(25,399

)

Other assets and liabilities

 

(6,088

)

 

 

531

 

Net cash used in operating activities

 

(20,918

)

 

 

(109,061

)

Investing activities

 

 

 

Consideration on escrow paid for GeneDx acquisition

 

 

 

 

(12,144

)

Purchases of property and equipment

 

(1,795

)

 

 

(2,762

)

Proceeds from sales of assets

 

 

 

 

3,634

 

Purchases of marketable securities

 

(29,381

)

 

 

 

Proceeds from sales of marketable securities

 

598

 

 

 

 

Proceeds from maturities of marketable securities

 

8,720

 

 

 

 

Development of internal-use software assets

 

 

 

 

(461

)

Net cash used in investing activities

 

(21,858

)

 

 

(11,733

)

Financing activities

 

 

 

Proceeds from offerings, net of issuance costs

 

 

 

 

143,002

 

Exercise of stock options

 

161

 

 

 

266

 

Long-term debt principal payments

 

 

 

 

(2,000

)

Finance lease payoff and principal payments

 

(990

)

 

 

(1,222

)

Net cash (used in) provided by financing activities

 

(829

)

 

 

140,046

 

Net (decrease) increase in cash, cash equivalents and restricted cash

 

(43,605

)

 

 

19,252

 

Cash, cash equivalents and restricted cash, at beginning of period

 

100,668

 

 

 

138,303

 

Cash, cash equivalents and restricted cash, at end of period (1)

$

57,063

 

 

$

157,555

 

 

 

 

 

Supplemental disclosures of cash flow information

 

 

 

Cash paid for interest

$

4,033

 

 

$

946

 

Cash paid for taxes

$

557

 

 

$

1,003

 

Stock consideration paid for purchase of business

$

 

 

$

6,692

 

Stock consideration paid pursuant to exercise of Perceptive warrant

$

12,586

 

 

$

 

Purchases of property and equipment in accounts payable and accrued expenses

$

501

 

 

$

109

 

Assets acquired under capital leases obligations

$

689

 

 

$

 

(1)

Cash, cash equivalents and restricted cash at June 30, 2024 excludes marketable securities of $50.8 million.

 

Investor Relations Contact:

Investors@GeneDx.com

Media Contact:

Press@GeneDx.com

Source: GeneDx

FAQ

What was GeneDx's revenue for Q2 2024?

GeneDx reported revenue from continuing operations of $68.9 million for Q2 2024, representing a 52% year-over-year increase.

How much did GeneDx's exome and genome test revenue grow in Q2 2024?

GeneDx's exome and genome test revenue grew 77% year-over-year to $50.7 million in Q2 2024.

What is GeneDx's updated revenue guidance for full-year 2024?

GeneDx raised its full-year 2024 revenue guidance to between $255 and $265 million.

When does GeneDx (WGS) expect to reach profitability?

GeneDx reiterated its expectation to reach profitability in 2025.

What was GeneDx's adjusted gross margin in Q2 2024?

GeneDx's adjusted gross margin from continuing operations expanded to 62% in Q2 2024, up from 37% in Q2 2023.

GeneDx Holdings Corp.

NASDAQ:WGS

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