Waters Otto SPEcialist Positive Pressure Manifold Improves Reproducibility and Reliability of Solid-Phase Extraction (SPE)

Rhea-AI Summary

Waters Corporation (NYSE:WAT) has launched the Otto SPEcialist Positive Pressure Manifold, designed to enhance the reliability of solid phase extraction (SPE) in laboratories. This semi-automated system features 21 CFR Part 11 compliant software that minimizes workflow errors and user variability, promoting reproducible results. The Otto SPEcialist system accommodates various SPE device sizes and provides precise control over sample processing. Unlike complex automated systems, it is user-friendly and requires minimal setup costs, making it an efficient solution for laboratories across pharmaceutical, biopharmaceutical, food and beverage, and environmental sectors.

Positive

• Launch of the Otto SPEcialist system enhances reproducibility and reliability of solid phase extraction (SPE).
• User-friendly software and programmable pressure profiles reduce workflow errors and user variability.
• Semi-automated system is cost-effective compared to fully automated SPE systems.
• Compatible with various sample plates and easily scalable for different applications.

Negative

• None.

Waters Corporation (NYSE:WAT) today introduced the Otto^TM SPEcialist Positive Pressure Manifold designed to improve the reliability and reproducibility of solid phase extraction (SPE). Equipped with easy-to-use, 21 CFR Part 11 compliant software and programmable pressure profiles, the Otto SPEcialist system provides confidence in SPE results by eliminating common workflow errors, reducing user variability, and documenting each method step to remove uncertainty and prevent duplicative efforts. By automating the various pressure applications of SPE, Otto helps laboratories achieve greater overall efficiency and is useful for a variety of pharmaceutical, biopharmaceutical food & beverage and environmental applications.

The Waters Otto SPEcialist Positive Pressure Manifold is a software-driven, semi-automated system that lets users program pressure profiles for more reliable and repeatable solid phase extraction methods. (Photo: Business Wire)

“Reproducible sample preparation is an essential component of successful analytical methods” said Erin Chambers, Vice President, Chemistry, Waters Corporation. “However, even straightforward workflows like solid-phase extraction may suffer from poor reproducibility due to technique-associated variation. Otto SPEcialist is an important tool for helping laboratories perform SPE in a controlled, reliable way. By reducing flow rate variation and ensuring method fidelity regardless of user or experience level, laboratories can more easily achieve success with ease while scaling operations and resources seamlessly.”

For LC and LC-MS/MS analyses, sample preparation like SPE, is a necessary first step best automated to ensure reliability and reproducibility, especially when screening or analyzing significant numbers of samples and when consistency is important. Controlled with the intuitive, 21 CFR Part 11 compliant-ready Otto Software through an integrated tablet, Otto SPEcialist system enables the creation, editing, running, and sharing of pressure profiles and methods with little-to-no training. By utilizing positive pressure applied to the top of the device to control flow rather than vacuum processing applied to the bottom, Otto SPEcialist system offers more precise control for easier and more reliable sample processing. The system provides a wide pressure control range, accommodating a number of SPE device sizes and sorbent masses. The Otto SPEcialist system also creates contact with each individual cartridge or well, unlike vacuum processing where all cartridges or wells are connected to a single source.

As compared to fully-automated SPE systems that are often complicated and costly to set up and run, the semi-automated Otto SPEcialist system – with easy-to-use software and a clean, simple interface – can be quickly deployed without significant capital investment. Users can create pressure profiles for every step of an SPE workflow – including load, wash and elution steps – at the push of a button. New and existing profiles, methods and processing parameters are tracked and documented, allowing for unfettered sharing across multiple days, users, laboratories, assays and Otto devices. This eliminates the variability associated with manual extraction procedures and ensures workflow consistency regardless of operator or environment.

Otto SPEcialist system is compatible with a variety of sample plates, including Waters 96-well plates as well as larger 1 cc, 3 cc, and 6 cc cartridges, to easily scale methods as needed.

Visit Waters’ website to learn more about the Otto SPEcialist Positive Pressure Manifold for smart and controlled processing of SPE, now available worldwide.

Additional Resources

• Download the white paper: Otto SPEcialist Positive Pressure Manifold for Semi-Automated SPE Processing
• Download the infographic: Otto SPEcialist infographic
• Watch the video: Otto SPEcialist Positive Pressure Manifold – How it Works
• For information about all of Waters products for laboratory automation: Check out our web site.
• Request a demo or pricing

About Waters Corporation (www.waters.com)

Waters Corporation (NYSE:WAT), the world's leading specialty measurement company, has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, food and environmental sciences for more than 60 years. With more than 7,000 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, and with products available in more than 100 countries.

Waters and Otto are trademarks of Waters Corporation.

View source version on businesswire.com: https://www.businesswire.com/news/home/20210127005318/en/

FAQ

What is the Otto SPEcialist Positive Pressure Manifold launched by Waters Corporation (WAT)?

The Otto SPEcialist Positive Pressure Manifold is a semi-automated system designed to improve the reliability and reproducibility of solid phase extraction (SPE) processes in laboratories.

How does the Otto SPEcialist system enhance laboratory efficiency?

By automating pressure applications and minimizing user variability, the Otto SPEcialist system increases workflow efficiency and consistency in SPE results.

What industries can benefit from the Otto SPEcialist system?

The Otto SPEcialist system is beneficial for laboratories in pharmaceutical, biopharmaceutical, food and beverage, and environmental sectors.

What compliance does the Otto SPEcialist software meet?

The Otto SPEcialist software is compliant with 21 CFR Part 11, ensuring regulatory standards are met.

How does the Otto SPEcialist system compare to fully automated SPE systems?

The Otto SPEcialist system is semi-automated, making it more user-friendly and cost-effective than fully automated systems, which are often complicated and expensive to set up.