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Vaxart, Inc. (symbol: VXRT) is a clinical-stage biotechnology company dedicated to transforming vaccine delivery through its innovative oral recombinant vaccine platform. Founded in 2004, Vaxart's primary focus is the development of vaccines in tablet form, offering a needle-free alternative that is easy to administer and store. This proprietary technology aims to revolutionize the global vaccine market, addressing common diseases such as Coronavirus, Norovirus, Seasonal Influenza, Respiratory Syncytial Virus (RSV), and Human Papillomavirus (HPV).
Headquartered in the United States, Vaxart operates in a single segment focused exclusively on the discovery and development of these groundbreaking oral recombinant protein vaccines. The company has made significant strides in the clinical development of its diverse pipeline, with several candidates currently undergoing trials. Vaxart’s oral vaccines are designed to simplify distribution and administration, potentially increasing vaccination rates and improving global health outcomes.
Recent achievements for Vaxart include the ongoing development and testing of its oral COVID-19 vaccine candidate, which has shown promise in preclinical studies and early-phase clinical trials. This innovation could play a crucial role in global vaccination efforts, especially in regions where cold-chain requirements pose logistical challenges. Other notable projects include the development of oral vaccines for Norovirus and Influenza, which are also advancing through various stages of clinical testing.
Financially, Vaxart remains focused on strategic partnerships and funding opportunities to support its research and development initiatives. The company's recent financial results for the full year ended December 31, 2023, and the first quarter ended March 31, 2024, reflect its ongoing commitment to advancing its oral vaccine candidates through clinical trials and towards regulatory approval.
For more information and the latest updates, contact Vaxart Media Relations: Mark Herr (mherr@vaxart.com, 203-517-8957) or Investor Relations: Andrew Blazier (IR@vaxart.com, 646-871-8486).
Vaxart, Inc. (Nasdaq: VXRT) is urging stockholders to vote on Proxy Proposal #2 by July 5, 2022, which seeks to increase authorized shares to 250 million. This proposal is backed by ISS and Glass Lewis, indicating strong support. Currently, 76% of present voting shares favor the proposal, but it requires more than 50% of all outstanding shares to pass. CEO Andrei Floroiu emphasizes that approval would enhance capital-raising flexibility, aiding Vaxart's promising pipeline and competitive position. Stockholders can vote online, by phone, or via mail.
Vaxart, Inc. (Nasdaq: VXRT) has entered an agreement with hVIVO Services Limited to develop a human challenge model based on the Omicron variant of SARS-CoV-2. This initiative aims to support a Phase II Human Challenge Trial of Vaxart's oral COVID-19 vaccine pill candidate. Vaxart is pioneering the use of an Omicron-specific challenge study, making it the first company to do so. The successful execution of the challenge study is expected to start in 2023, contingent upon regulatory approvals.
Vaxart, Inc. (Nasdaq: VXRT) announced a Q&A webcast with investors and analysts on June 22, 2022, at 1:00 p.m. ET, featuring CEO Andrei Floroiu, SVP Dr. Sean Tucker, and CMO Dr. James Cummings. They will discuss the company's oral vaccine programs and answer submitted questions. The event will be available for replay two hours after its conclusion on Vaxart's website. Additionally, Vaxart’s 2022 annual meeting has been rescheduled to July 6, 2022, at 12:30 p.m. ET, encouraging stockholders to vote by July 5, 2022.
Vaxart, Inc. (Nasdaq: VXRT) has announced the adjournment of its 2022 annual meeting of stockholders to July 6, 2022, at 9:30 a.m. PT. Stockholders of record as of April 11, 2022, are encouraged to vote by July 5, 2022, at 11:59 p.m. ET. Approximately 58.22% of shares were voted, with key proposals mostly approved, except for an amendment to increase authorized shares. This amendment's failure may hinder Vaxart's abilities in raising capital and strategic planning. The meeting will be accessible via live webcast.
Vaxart (NASDAQ: VXRT) reported promising preliminary preclinical data for its COVID-19 vaccine candidates targeting the SARS-CoV-2 variants. Both the Wuhan and Omicron specific vaccines demonstrated protective effects in hamsters against the Omicron BA.1 variant, with the Omicron candidate showing superior antibody response. Weight loss and viral load were reduced in vaccinated animals compared to unvaccinated ones. Vaxart continues to leverage evolving pandemic data for vaccine development strategies, advancing toward clinical trials.
Vaxart (NASDAQ: VXRT) announced positive preliminary results from its Phase 1b trial of an oral norovirus vaccine for adults aged 55 to 80. The study showed a robust immune response with a dose-dependent increase in IgA antibody secreting cells, alongside a favorable safety profile. These results support the development of the vaccine in elderly populations. The company is conducting a Phase 2 clinical challenge study and reported encouraging data from a booster study, allowing for improved antibody responses. Norovirus costs the U.S. healthcare system an estimated $10.6 billion annually.
Vaxart, Inc. (Nasdaq: VXRT) announced that its leadership team, including CEO Andrei Floroiu, will participate in a fireside chat at the Jefferies Global Healthcare Conference on June 9, 2022, at 10:30 a.m. ET. The event will be streamed live on the Company’s website, with a replay available afterward. Vaxart specializes in developing oral recombinant vaccines and is currently working on vaccines targeting coronavirus, norovirus, seasonal influenza, and RSV, among others. The company is committed to innovative delivery methods for vaccines that require no refrigeration.
Vaxart (NASDAQ: VXRT) announced significant findings from a preclinical hamster study, suggesting its S-only oral COVID-19 vaccine candidate effectively inhibits SARS-CoV-2 transmission. The study highlighted a reduction in infectious virus and transmission among vaccinated hamsters. Additionally, Phase 1 results showed the S+N vaccine candidate stimulated cross-reactive IgA antibodies, indicating potential effectiveness against various coronaviruses. The results were published in Science Translational Medicine, reinforcing Vaxart's oral vaccine development strategy. Future Phase II results are expected later this year.
Vaxart, Inc. (NASDAQ: VXRT) reported an update for Q1 2022, highlighting progress on oral vaccine candidates, including norovirus and COVID-19. The company ended the quarter with $157.0 million in cash and reported a net loss of $25.1 million, up from $16.0 million a year prior. Revenue fell to $85,000 from $506,000 year-over-year, primarily due to decreased royalty revenue. Key results from clinical trials for its COVID-19 and norovirus vaccines are expected in the upcoming quarters.
Vaxart, Inc. (Nasdaq: VXRT) announced that Dr. Sean Tucker, SVP and Chief Scientific Officer, will present at the World Vaccine Congress Washington 2022 on April 20, 2022, at 3:55 p.m. ET. His presentation is titled “Moving the needle: Blocking transmission and boosting existing vaccines by oral tablet vaccination.” Dr. Tucker will share data highlighting the potential benefits of Vaxart’s oral tablet COVID-19 vaccine candidate, which is currently in clinical development.
Vaxart develops oral recombinant vaccines that can be stored without refrigeration, aiming to create vaccines for various diseases, including coronavirus and HPV.
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