Verona Pharma plc - VRNA STOCK NEWS

Verona Pharma, a clinical-stage biopharmaceutical company, has completed the enrollment of over 800 subjects in its Phase 3 ENHANCE-2 trial, which evaluates ensifentrine for chronic obstructive pulmonary disease (COPD) maintenance treatment. The top-line data is expected in the third quarter of 2022. CEO David Zaccardelli noted that reaching this milestone during the ongoing pandemic is significant. The trial aims to demonstrate the efficacy of ensifentrine, which combines bronchodilator and anti-inflammatory effects, in improving lung function and quality of life for COPD patients.

Verona Pharma (Nasdaq: VRNA) has completed screening for the ENHANCE-2 trial, enrolling 788 subjects with full enrollment expected by January's end. The Phase 3 program focuses on ensuring ensifentrine, a novel nebulized treatment for chronic obstructive pulmonary disease (COPD), shows efficacy and safety. Top-line data is anticipated in 2022, potentially leading to a New Drug Application with the FDA in early 2023. As of December 31, 2021, the company reported $148.4 million in cash, sufficient to cover operations through at least 2023.

Verona Pharma (Nasdaq: VRNA) announced that David Zaccardelli, Pharm. D., the CEO, will present an overview of the company at the H.C. Wainwright BioConnect Virtual Conference. The presentation will be available on-demand from 7:00 AM EST / 12:00 PM GMT on January 10, 2022. Interested parties can access a webcast of the event for 90 days via the company's website's Investors page. Verona Pharma focuses on developing innovative therapies for respiratory diseases, with its product candidate ensifentrine currently in Phase 3 development for COPD.

Verona Pharma has successfully completed a thorough QT study for its product candidate ensifentrine, showing no adverse effects on cardiac conduction in healthy individuals. This study is essential for the NDA submission for ensifentrine, aimed at treating COPD. The results will support the ongoing Phase 3 clinical trial program, ENHANCE, with expected data reporting in 2022. Ensifentrine, if approved, could become the first treatment combining bronchodilator and anti-inflammatory properties for respiratory diseases.

Verona Pharma reports its financial results for Q3 2021, revealing significant advancements in its ENHANCE Phase 3 clinical program for ensifentrine, targeting respiratory diseases. As of November 8, 2021, enrollment in ENHANCE-2 is approximately 90% complete, while the 48-week subset of ENHANCE-1 is about 95% enrolled. The company expects to conclude enrollment by year-end 2021 and release top-line data in mid-2022. Financially, revenues reached $40 million, supported by a new agreement with Nuance Pharma, and net profit improved to $11.1 million, a significant turnaround from a loss the previous year.

Verona Pharma plc (Nasdaq: VRNA) announced its participation in three investor conferences this November 2021. David Zaccardelli, CEO, will present at the Stifel Virtual Healthcare Conference on November 15, the Jefferies London Healthcare Conference on November 18, and the Piper Sandler Annual Virtual Healthcare Conference on November 29. The presentations will cover Verona's innovative respiratory therapies, including ensifentrine, which targets COPD and other respiratory diseases. Webcasts of the presentations will be available on the company's investor relations page.

Verona Pharma (Nasdaq: VRNA) will announce its financial results for Q3 and nine months ending September 30, 2021, on November 9, 2021, followed by a conference call at 9:00 a.m. EST. Investors can join via telephone or live webcast. Verona Pharma is developing ensifentrine, a novel therapy for respiratory diseases, currently in Phase 3 for COPD. The success of ensifentrine could make it the first dual-action treatment combining bronchodilation and anti-inflammatory effects. Further details available on their website.

Verona Pharma (Nasdaq: VRNA) announced Phase 2 data showing favorable effects of ensifentrine, delivered via a pressurized metered-dose inhaler (pMDI), on patients with moderate to severe chronic obstructive pulmonary disease (COPD). Presented at the CHEST Annual Meeting 2021, the study indicated significant improvements in lung function and tolerability akin to placebo. The ongoing global Phase 3 trial is expected to yield results in 2022. Ensifentrine is a first-in-class dual inhibitor of phosphodiesterase 3 and 4, promising both bronchodilator and anti-inflammatory effects.

Verona Pharma (Nasdaq: VRNA) announced the publication of an abstract regarding a study on the drug-drug interaction between fluconazole and ensifentrine, presented at the European Respiratory Society International Congress 2021. The Phase 1 study indicated that co-administration of fluconazole with nebulized ensifentrine showed minimal, clinically irrelevant effects on ensifentrine pharmacokinetics. The company continues its Phase 3 program for ensifentrine to treat COPD, with top-line results expected in 2022.