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Volition hosts NETs in sepsis management symposium at ESICM Lives 2024

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VolitionRx (NYSE AMERICAN: VNRX) is hosting a symposium at ESICM Lives 2024 in Barcelona on October 7, 2024. The session, titled 'NETs: Casting a new light on sepsis management', will feature experts presenting findings from large, independent studies on using Nu.Q® NETs to enhance sepsis management.

Professor Djillali Annane, chair of the symposium, highlights the potential of Nu.Q® NETs H3.1 assay in clinical practice for sepsis management. The symposium will explore the role of H3.1 nucleosomes in NETosis, the clinical utility of H3.1 in recent large-scale studies, and how Nu.Q® NETs biomarker could predict organ failure.

Nu.Q® NETs is Volition's technology that quantifies circulating H3.1 nucleosomes in the bloodstream, a surrogate marker for Neutrophil Extracellular Traps (NETs). Elevated levels of NETs can lead to tissue damage, sepsis, organ failure, and death.

VolitionRx (NYSE AMERICAN: VNRX) ospiterà un simposio all'ESICM Lives 2024 a Barcellona il 7 ottobre 2024. La sessione, intitolata 'NETs: un nuovo sguardo sulla gestione della sepsi', vedrà esperti presentare i risultati di ampi studi indipendenti sull'uso di Nu.Q® NETs per migliorare la gestione della sepsi.

Il Professore Djillali Annane, presidente del simposio, sottolinea il potenziale del test Nu.Q® NETs H3.1 nella pratica clinica per la gestione della sepsi. Il simposio esplorerà il ruolo dei nucleosomi H3.1 nella NETosi, l'utilità clinica dell'H3.1 in recenti studi su larga scala e come il biomarcatore Nu.Q® NETs possa prevedere l'insufficienza d'organo.

Nu.Q® NETs è la tecnologia di Volition che quantifica i nucleosomi H3.1 circolanti nel flusso sanguigno, un marcatore surrogato per i Neutrophil Extracellular Traps (NETs). Livelli elevati di NETs possono portare a danni tissutali, sepsi, insufficienza d'organo e morte.

VolitionRx (NYSE AMERICAN: VNRX) organizará un simposio en el ESICM Lives 2024 en Barcelona el 7 de octubre de 2024. La sesión, titulada 'NETs: Arrojando nueva luz sobre la gestión de la sepsis', contará con expertos presentando hallazgos de grandes estudios independientes sobre el uso de Nu.Q® NETs para mejorar la gestión de la sepsis.

El Profesor Djillali Annane, presidente del simposio, destaca el potencial del ensayo Nu.Q® NETs H3.1 en la práctica clínica para la gestión de la sepsis. El simposio explorará el papel de los nucleosomas H3.1 en la NETosis, la utilidad clínica del H3.1 en recientes estudios a gran escala y cómo el biomarcador Nu.Q® NETs podría predecir la insuficiencia orgánica.

Nu.Q® NETs es la tecnología de Volition que cuantifica los nucleosomas H3.1 circulantes en el torrente sanguíneo, un marcador sustituto para las trampas extracelulares de neutrófilos (NETs). Los niveles elevados de NETs pueden provocar daño tisular, sepsis, insuficiencia orgánica y muerte.

VolitionRx (NYSE AMERICAN: VNRX)는 2024년 10월 7일 바르셀로나의 ESICM Lives 2024에서 심포지엄을 개최합니다. 'NETs: 패혈증 관리에 대한 새로운 통찰력'이라는 제목의 세션에서는 Nu.Q® NETs를 사용하여 패혈증 관리를 개선하는 대규모 독립 연구 결과를 발표하는 전문가들이 참여할 것입니다.

심포지엄 의장인 Djillali Annane 교수는 패혈증 관리에서 Nu.Q® NETs H3.1 검사법의 잠재력을 강조합니다. 심포지엄에서는 NETosis에서 H3.1 핵산의 역할, 최근 대규모 연구에서 H3.1의 임상 유용성, 그리고 Nu.Q® NETs 바이오마커가 장기 부전을 예측할 수 있는 방법에 대해 탐구할 것입니다.

Nu.Q® NETs는 혈류에서 순환하는 H3.1 핵산을 정량화하는 Volition의 기술로, 호중구 세포외 그물(NETs)의 대체 마커입니다. NETs의 수치가 상승하면 조직 손상, 패혈증, 장기 부전 및 사망으로 이어질 수 있습니다.

VolitionRx (NYSE AMERICAN: VNRX) organise un symposium lors de ESICM Lives 2024 à Barcelone le 7 octobre 2024. La session, intitulée 'NETs : Un nouvel éclairage sur la gestion de la sepsie', mettra en avant des experts présentant les résultats d'importantes études indépendantes sur l'utilisation de Nu.Q® NETs pour améliorer la gestion de la sepsie.

Le Professeur Djillali Annane, président du symposium, souligne le potentiel du test Nu.Q® NETs H3.1 dans la pratique clinique pour la gestion de la sepsie. Le symposium explorera le rôle des nucléosomes H3.1 dans la NETose, l'utilité clinique du H3.1 dans des études récentes à grande échelle, et comment le biomarqueur Nu.Q® NETs pourrait prédire l'insuffisance organique.

Nu.Q® NETs est la technologie de Volition qui quantifie les nucléosomes H3.1 circulants dans le sang, un marqueur de substitution pour les pièges extracellulaires de neutrophiles (NETs). Des niveaux élevés de NETs peuvent entraîner des lésions tissulaires, de la sepsie, une insuffisance organique et la mort.

VolitionRx (NYSE AMERICAN: VNRX) veranstaltet am 7. Oktober 2024 ein Symposium bei ESICM Lives 2024 in Barcelona. Die Sitzung mit dem Titel 'NETs: Ein neuer Blick auf das Management von Sepsis' wird Experten präsentieren, die Ergebnisse aus großen, unabhängigen Studien zur Anwendung von Nu.Q® NETs zur Verbesserung des Sepsis-Managements vorstellen.

Professor Djillali Annane, der Vorsitzende des Symposiums, hebt das Potenzial des Nu.Q® NETs H3.1 Tests in der klinischen Praxis für das Sepsis-Management hervor. Das Symposium wird die Rolle der H3.1-Nukleosomen in der NETose, die klinische Anwendbarkeit von H3.1 in aktuellen Großstudien und wie der Biomarker Nu.Q® NETs organische Versagen vorhersagen könnte, erörtern.

Nu.Q® NETs ist die Technologie von Volition, die die zirkulierenden H3.1-Nukleosomen im Blutstrom quantifiziert, ein Surrogatmarker für Neutrophil Extracellular Traps (NETs). Erhöhte Werte von NETs können zu Gewebeschäden, Sepsis, Organversagen und Tod führen.

Positive
  • Volition is hosting a symposium at a major international medical conference (ESICM Lives 2024)
  • Experts will present findings from large, independent studies on Nu.Q® NETs for sepsis management
  • Nu.Q® NETs technology has potential to predict organ failure in sepsis cases
  • Nu.Q® NETs is described as a simple, low-cost, and accessible test
Negative
  • None.

HENDERSON, Nev., Oct. 3, 2024 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, is hosting a symposium at ESICM Lives 2024 in Barcelona on October 7, 2024, during which experts from across the globe will present findings from large, independent studies regarding the potential of using Nu.Q® NETs to determine a 'treatable trait' to enhance sepsis management.

The session, entitled 'NETs: Casting a new light on sepsis management', will take place at 12.30 pm CET on Monday, October 7, and will be chaired by Professor Djillali Annane, a world-renowned expert in sepsis.

Professor Djillali Annane, Professor of Medicine at University Paris Saclay-UVSQ, said:

"Volition's ESICM symposium will bring together distinguished experts in the field of sepsis to share research findings around the potential use of Volition's Nu.Q® NETs H3.1 assay in clinical practice. 

"It is becoming increasingly evident that Nu.Q® NETs could play an integral role in the management of sepsis. Elevated levels of H3.1 are both a marker of badness and a cause of consequence. During the session, we will explore the role of H3.1 nucleosomes in NETosis; the clinical utility of H3.1 in a range of recent, large-scale studies, and examine how the Nu.Q® NETs biomarker has the potential to predict organ failure.

"As a Critical Care Consultant, I see the devastating effects of this disease each day. I believe Nu.Q® NETs, as a diagnostic tool, has the potential to bring about a paradigm shift in sepsis management. I hope that Nu.Q® NETs becomes widely available - in every intensive care unit, in every hospital setting - to help ensure we detect, treat, and monitor sepsis earlier and save lives."

Nu.Q® NETs, Volition's nucleosome quantification technology, is a simple, low-cost, accessible test that quantifies an individual's level of circulating H3.1 nucleosomes in the bloodstream, a surrogate marker for Neutrophil Extracellular Traps (NETs). Although NETs play a critical role in our normal immune response, elevated levels of NETs can lead to tissue damage, and in severe cases, sepsis, organ failure and death.

ESICM Lives 2024 is the annual congress of the European Society of Intensive Care Medicine and brings together intensive care physicians, anesthetists, nursing, and allied health professionals from over 100 countries worldwide.

Note:

Sepsis is the number one cause of death in hospitals worldwide and accounts for at least 11 million deaths per year (Global Sepsis Alliance 2024).

About Volition

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help diagnose and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early diagnosis and monitoring have the potential not only to prolong the life of patients, but also improve their quality of life. For more information about Volition's technology go to: www.volition.com.

Volition's research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and additional offices in London and Singapore. 

The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

Safe Harbor Statement

Statements in this press release may be "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as "expects," "anticipates," "intends," "plans," "aims," "targets," "believes," "seeks," "estimates," "optimizing," "potential," "goal," "suggests," "could," "would," "should," "may," "will" and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, the potential uses, benefits and effectiveness of Volition's Nu.Q® technology platform. Volition's actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition's failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition's development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition's failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition's intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition's business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this press release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

Nucleosomics™, Capture-PCR™ and Nu.Q® and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release are the property of their respective owners. 

Media Enquiries:
Louise Batchelor/Debra Daglish
Volition
mediarelations@volition.com
+44 (0)7557 774620

Cision View original content:https://www.prnewswire.com/news-releases/volition-hosts-nets-in-sepsis-management-symposium-at-esicm-lives-2024-302266731.html

SOURCE VolitionRx Limited

FAQ

What is Volition presenting at ESICM Lives 2024?

Volition is hosting a symposium titled 'NETs: Casting a new light on sepsis management' at ESICM Lives 2024 in Barcelona on October 7, 2024. The symposium will present findings from large, independent studies on using Nu.Q® NETs to enhance sepsis management.

What is Nu.Q® NETs and how does it relate to sepsis management for VNRX?

Nu.Q® NETs is Volition's nucleosome quantification technology that measures circulating H3.1 nucleosomes in the bloodstream, serving as a surrogate marker for Neutrophil Extracellular Traps (NETs). It has potential applications in sepsis management, including predicting organ failure and improving early detection and treatment of sepsis.

When and where is Volition (VNRX) hosting its symposium on NETs and sepsis management?

Volition (VNRX) is hosting its symposium on NETs and sepsis management at ESICM Lives 2024 in Barcelona on October 7, 2024, at 12:30 pm CET.

Who is chairing Volition's symposium at ESICM Lives 2024?

Professor Djillali Annane, a world-renowned expert in sepsis and Professor of Medicine at University Paris Saclay-UVSQ, is chairing Volition's symposium at ESICM Lives 2024.

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