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Vir Biotechnology, Inc. (Nasdaq: VIR) is a prominent immunology company pioneering the use of advanced technological innovations to address some of the globe's most challenging infectious diseases. Combining leading scientific expertise with management prowess, Vir Biotechnology focuses on creating solutions for diseases that currently have inadequate or non-existent treatments.
Vir's core business revolves around leveraging breakthroughs in immune programming to manipulate pathogen-host interactions effectively. The company employs a multi-program, multi-platform approach, guided by rigorous science and driven by significant medical needs. Its technology platforms comprise antibodies, T cells, innate immunity, and small interfering ribonucleic acid (siRNA).
The company's product pipeline targets severe infectious diseases, including hepatitis B (HBV), influenza A, human immunodeficiency virus (HIV), and tuberculosis (TB). Vir's revenue streams come from various sources, including collaboration revenue, contract revenue, grant revenue, and license revenue.
Vir's strategy includes internal development, collaborations, and acquisitions, positioning itself as a leader in the biotech space. Notably, Vir's recent collaboration with Brii Biosciences has led to significant advancements in the pursuit of a functional cure for HBV. Through this partnership, they have achieved Breakthrough Therapy Designations for BRII-877 and BRII-835, investigational treatments targeting HBV and chronic hepatitis D virus (HDV) infections.
The company's latest achievements highlight its focus on developing effective therapeutic regimens for chronic HBV infection, a disease affecting over 254 million people globally. With ongoing clinical trials and a commitment to scientific excellence, Vir Biotechnology is at the forefront of transforming the treatment landscape for infectious diseases.
Vir Biotechnology announced the appointment of Mark D. Eisner, M.D., M.P.H. as Executive Vice President and Chief Medical Officer (CMO), effective June 03, 2024. Dr. Eisner brings over 32 years of experience in biotech, with deep expertise in immunology and infectious diseases. He previously held the CMO position at Sonoma Biotherapeutics and FibroGen, and served as Senior Vice President at Genentech, leading late-stage clinical development across multiple therapeutic areas. Dr. Eisner's role at Vir will involve overseeing clinical development programs and contributing to the company's growth by advancing medicines for unmet medical needs.
Vir Biotechnology (Nasdaq: VIR) will hold its 2024 Annual Meeting of Stockholders on May 29, 2024, at 9:00 a.m. PT. The meeting will be conducted virtually via live audio webcast. Stockholders of record at the close of business on April 1, 2024, are eligible to attend and vote. Participants can access the meeting through the provided web link using their control number. Online access will begin at 8:45 a.m. PT on the day of the meeting. Vir Biotechnology encourages all stockholders to vote and submit their proxies in advance.
Vir Biotechnology announced that three abstracts focusing on chronic hepatitis delta and hepatitis B will be presented at the EASL Congress 2024 in Milan from June 5-8.
The presentations include new data from the Phase 2 SOLSTICE trial, evaluating the safety and efficacy of tobevibart and elebsiran in chronic hepatitis delta patients.
Key highlights include 12 and 24-week treatment data, as well as 48-week data for a subset of participants.
Additional 24-week data on all 60 participants will be reported in Q4 2024. An investor conference call is scheduled for June 5 to discuss these findings.
Vir Biotechnology announced that the European Association for the Study of the Liver (EASL) Congress 2024 has upgraded its Phase 2 SOLSTICE hepatitis delta presentation from a late-breaker poster to an oral presentation. The presentation will take place on June 8 during the EASL Congress in Milan, Italy, which runs from June 5-8. The company will also host an investor call on June 5 to discuss the new SOLSTICE data, including 12-week and 24-week treatment outcomes. Additional 48-week data on the efficacy and safety of tobevibart and elebsiran will be provided, complementing data shared at the 2023 AASLD Liver Meeting.
Brii Biosciences announced that the National Medical Products Administration (NMPA) has granted Breakthrough Therapy Designations for two of its investigational therapies: BRII-877 (tobevibart) and BRII-835 (elebsiran). These therapies target hepatitis B virus (HBV) and are supported by extensive Phase 1 and 2 studies. BRII-877 has treated over 350 patients, showing well-tolerated results and significant decreases in HBsAg levels. BRII-835, studied in over 570 patients, demonstrated robust antiviral activity against HBV. These designations bolster Brii Bio’s ongoing efforts to develop functional cures for chronic HBV and HDV infections, enhancing their therapeutic regimens to achieve higher cure rates in broader patient populations.
Vir Biotechnology provided a corporate update and reported financial results for the first quarter of 2024. They announced the acceptance of late-breaker SOLSTICE data abstract for poster presentation at the EASL Congress 2024, with two additional hepatitis program data readouts on track for the fourth quarter. The company had $1.51 billion in cash, cash equivalents, and investments as of March 31, 2024. Key pipeline programs include Chronic Hepatitis Delta and Chronic Hepatitis B, with abstracts accepted for poster presentation at the EASL Congress 2024. Additionally, the Company is advancing next-generation antibodies using its proprietary platform and expects to file multiple investigational new drug applications within the next 18 months.
Vir Biotechnology, Inc. (Nasdaq: VIR) CEO Marianne De Backer will participate in a fireside chat at the BofA Securities Healthcare Conference 2024 on May 14. The event will be live webcasted and archived on the Vir website.
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