Vigil Neuroscience to Host ALSP KOL Event on December 6, 2022

Rhea-AI Summary

Vigil Neuroscience (Nasdaq: VIGL) will host a Key Opinion Leader (KOL) event on December 6, 2022, in New York City, focusing on adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). The event aims to discuss the disease background, epidemiology, and the Phase 2 trial design for VGL101, the company’s lead product candidate targeting TREM2. The event features expert speakers and will be accessible via a live webcast. Vigil Neuroscience is dedicated to developing treatments for neurodegenerative diseases by restoring microglial function.

CAMBRIDGE, Mass., Nov. 28, 2022 (GLOBE NEWSWIRE) -- Vigil Neuroscience, Inc. (Nasdaq: VIGL), a clinical-stage biotechnology company committed to harnessing the power of microglia for the treatment of neurodegenerative diseases, today announced that the Company will host an adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) Key Opinion Leader (KOL) event for the investment community in New York City on Tuesday, December 6, 2022, from 8:30 a.m. – 11:30 a.m. ET.

The event will provide further details on the ALSP disease background, epidemiology and patient journey. In addition, the Company plans to present the VGL101 Phase 2 trial design and objectives as well as interim MRI data from Illuminate, the ongoing natural history study. The Vigil management team will be joined by:

• David S. Lynch, MD, PhD, Consultant Neurologist, National Hospital for Neurology & Neurosurgery, Queen Square & UCL Institute of Neurology and Clinical Lead, Adult Inherited White Matter Disorders Highly Specialist Service, NHS England;
• Christina Sundal, MD, PhD, CEO Neuroclinic Norway and Senior Consultant University Hospital Oslo, Norway; and
• Troy Lund, MSMS, PhD, MD, FAAP, Leukodystrophy Center of Excellence Division of Pediatric Blood and Marrow Transplantation & Cellular Therapy, University of Minnesota, A NORD Rare Disease Center of Excellence.
  

To access a live webcast of this event, please visit “Events & Presentations” in the “Investors” section of the Vigil website at www.vigilneuro.com. An archived replay will be available for approximately 90 days following the presentation.

Internet Posting of Information
Vigil Neuroscience routinely posts information that may be important to investors in the “Investors” section of its website at https://www.vigilneuro.com. The company encourages investors and potential investors to consult our website regularly for important information about Vigil Neuroscience.

About VGL101
VGL101, Vigil’s lead product candidate, is a fully human monoclonal antibody targeting human triggering receptor expressed on myeloid cells 2 (TREM2), which is responsible for maintaining microglial cell function. TREM2 deficiency is believed to be a driver of certain neurodegenerative diseases. VGL101 is in development for rare microgliopathies, such as adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), as well as other neurodegenerative diseases for which TREM2 and/or microglia deficiency is believed to be a key driver of disease pathway.

About ALSP
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a rare, inherited, autosomal dominant neurological disease with high penetrance. It is caused by a mutation to the CSF1R gene and affects an estimated 10,000 people in the US, with similar prevalence in Europe and Japan. The disease generally presents itself in adults in their forties, is diagnosed through genetic testing and established clinical/radiologic criteria and is characterized by cognitive dysfunction, neuropsychiatric symptoms, and motor impairment. These symptoms typically exhibit rapid progression with a life expectancy of approximately six to seven years on average after diagnosis, causing significant patient and caregiver burden. There are currently no approved therapies for the treatment of ALSP, underlining the high unmet need in this rare indication.

About Vigil Neuroscience
Vigil Neuroscience is a clinical-stage, microglia-focused therapeutics company focused on developing treatments for both rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. We are utilizing the tools of modern neuroscience drug development across multiple therapeutic modalities in our efforts to develop precision-based therapies to improve the lives of patients and their families.

FAQ

What is the date of Vigil Neuroscience's KOL event focusing on ALSP?

The KOL event will take place on December 6, 2022.

Where is the Vigil Neuroscience KOL event being held?

The event is being held in New York City.

What disease is the focus of Vigil Neuroscience's upcoming event?

The focus is on adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP).

What will be discussed at the Vigil Neuroscience KOL event?

The event will cover ALSP disease background, epidemiology, patient journey, and VGL101 Phase 2 trial details.

How can I access the Vigil Neuroscience event?

You can access a live webcast through the 'Events & Presentations' section of Vigil's website.

What is VGL101 and its significance in the context of ALSP?

VGL101 is Vigil's lead product candidate targeting TREM2, aiming to address the needs of ALSP patients, for whom no therapies are currently approved.