Vera Therapeutics Reports First Quarter 2021 Financial Results and Provides Corporate Update

Rhea-AI Summary

Vera Therapeutics, Inc. (Nasdaq: VERA) reported its Q1 2021 financial results and corporate updates on June 24, 2021. The company initiated the Phase 2b ORIGIN clinical trial for atacicept aimed at treating IgA nephropathy. Vera raised approximately $128 million in total over nine months, including $48.4 million from its public offering in May 2021. The net loss for Q1 was $4.7 million, with cash and equivalents at approximately $49.5 million as of March 31, 2021. Key personnel appointments were made to enhance clinical and operational capabilities.

Positive

• Initiated Phase 2b ORIGIN clinical trial for atacicept targeting IgA nephropathy.
• Raised approximately $128 million over nine months, supporting clinical development efforts.

Negative

• Reported a net loss of $4.7 million for Q1 2021, up from $2.5 million year-over-year.
• Net cash used in operating activities increased to $4.1 million from $2.3 million year-over-year.

Completed an initial public offering with net proceeds, including the exercise of the underwriters’ option in full, of approximately $48.4 million in May 2021
- - -
Expanded the management team to support initiation
of atacicept clinical development program
- - -
Initiated Phase 2b ORIGIN clinical trial of atacicept in patients with IgA nephropathy (IgAN)

SOUTH SAN FRANCISCO, Calif., June 24, 2021 (GLOBE NEWSWIRE) -- Vera Therapeutics, Inc. (Nasdaq: VERA), a clinical-stage biotechnology company focused on developing and commercializing transformative treatments for patients with serious immunological diseases, today reported its financial results for the first quarter ended March 31, 2021, and provided a corporate update.

“Over the past nine months, we completed two capital raises for a total of approximately $128.0 million with which we have launched our clinical development program for atacicept,” said Marshall Fordyce, MD, founder and chief executive officer of Vera Therapeutics. “We recently initiated the Phase 2b ORIGIN trial of atacicept to treat IgAN, which we believe could have a profound benefit for patients for whom there remains significant unmet medical need.”

First Quarter and Recent Business Highlights

• Initiated the Phase 2b ORIGIN clinical trial, a dose-ranging study evaluating the safety and efficacy of atacicept in patients with IgA nephropathy (IgAN) who continue to have persistent proteinuria and remain at high risk of disease progression.
• Appointed Celia Lin, MD, as Chief Medical Officer, who brings extensive clinical and industry experience in orphan diseases and multiple therapeutic areas, including nephrology and inflammation.
• Appointed Tad Thomas, PhD, as Senior Vice President and Head of Product Development and Manufacturing to lead the Company’s process development, manufacturing, analytical sciences, and quality control operations.
• Appointed Joseph Young, MBA, as Senior Vice President of Finance and Chief Accounting Officer to oversee finance and accounting, administration, and corporate operations.
• Completed an initial public offering with net proceeds of approximately $48.4 million, including the underwriters’ exercise of their option in full, in May 2021.
• Completed an approximately $80.0 million Series C financing in January 2021 led by Abingworth LLP. Other investors included Sofinnova Investments, Longitude Capital, Fidelity Management & Research Company LLC, Surveyor Capital (a Citadel company), Octagon Capital, Kleiner Perkins, GV (formerly Google Ventures), and Alexandria Venture Investments.

Financial Results for the Quarter Ended March 31, 2021

For the three months ended March 31, 2021, the Company reported a net loss of $4.7 million, or a net loss per diluted share of $12.23, compared to a net loss of $2.5 million, or a net loss per diluted share of $7.79, for the same period last year.

During the first quarter 2021, net cash used in operating activities was $4.1 million, compared to $2.3 million for the same period last year.

Vera reported approximately $49.5 million in cash and cash equivalents as of March 31, 2021. Subsequently, Vera completed an initial public offering of 5,002,500 shares of its Class A common stock, including the underwriters’ exercise of their option in full, for net proceeds of approximately $48.4 million in May 2021.

About Atacicept
Atacicept is a novel, disease-modifying fully humanized fusion protein that is a dual inhibitor of the cytokines B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL). These cytokines are members of the tumor necrosis factor family that promote B-cell survival and autoantibody production associated with immunologic diseases, including IgA nephropathy (IgAN), also known as Berger’s disease, and systemic lupus erythematosus. Vera believes that atacicept has the potential to be the best-in-class and the leading B cell-targeted therapy for IgAN. Atacicept has been well tolerated and has been used in clinical trials of more than 1,500 patients to date. In a clinical trial of IgAN patients, data show atacicept is the first known molecule to substantially reduce galactose-deficient immunoglobulin A (Gd-IgA1).

About Vera
Vera Therapeutics is a clinical-stage biotechnology company focused on developing and commercializing transformative treatments for patients with serious immunological diseases. Vera’s lead product candidate is atacicept, a fusion protein self-administered as a subcutaneous injection once weekly that blocks both B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL), which stimulate B cells and plasma cells to produce autoantibodies contributing to certain autoimmune diseases. In addition, Vera is evaluating additional diseases where the reduction of autoantibodies by atacicept may prove medically useful, including lupus nephritis, a severe renal manifestation of systemic lupus erythematosus. For more information, please visit www.veratx.com.

Forward-looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements regarding, among other things, the strength of Vera’s balance sheet and the adequacy of cash and cash equivalents on hand. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as “plans,” “will”, “anticipates,” “goal,” “potential” and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Vera’s current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks and uncertainties associated with Vera’s business in general, the impact of the COVID-19 pandemic, and the other risks described in Vera’s filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management’s assumptions and estimates as of such date. Vera undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

Contacts

Investor Contact:
IR@veratx.com

Media Contact:
Greig Communications, Inc.
Kathy Vincent
(310) 403-8951
kathy@greigcommunications.com

VERA THERAPEUTICS, INC.
Unaudited Condensed Statements of Operations and Comprehensive Loss
(in thousands, except share and per share amounts)
	Three Months Ended
	March 31,
		2021				2020
Operating expenses:
Research and development	$	2,932			$	1,439
General and administrative		1,784				1,032
Total operating expenses		4,716				2,471
Loss from operations		(4,716	)			(2,471	)
Total other income (expense)		2				(3	)
Net loss and comprehensive loss	$	(4,714	)		$	(2,474	)
Net loss per share attributable to common stockholders, basic and diluted	$	(12.23	)		$	(7.79	)
Weighted-average shares of common stock outstanding, basic and diluted		385,401				317,693

VERA THERAPEUTICS, INC.
Condensed Balance Sheets
(in thousands)
			March 31,				December 31,
				2021				2020
Assets			(unaudited)
Current assets:
	Cash and cash equivalents		$	49,505			$	53,654
	Restricted cash, current			50				50
	Prepaid expenses and other current assets			1,977				557
		Total current assets		51,532				54,261
Restricted cash, noncurrent				293				293
		Total assets	$	51,825			$	54,554
Liabilities, redeemable convertible preferred stock, and stockholders' deficit
Current liabilities:
	Accounts payable		$	1,440			$	909
	Restructuring liability, current			515				962
	Accrued expenses and other current liabilities			1,798				535
		Total current liabilities		3,753				2,406
Restructuring liability, noncurrent				1,526				1,634
Accrued and other noncurrent liabilities				286				286
		Total liabilities		5,565				4,326
Redeemable convertible preferred stock				139,576				139,576
Stockholders' deficit
	Common stock			—				—
	Additional paid-in-capital			2,845				2,099
	Accumulated deficit			(96,161	)			(91,447	)
		Total stockholders' deficit		(93,316	)			(89,348	)
		Total liabilities, redeemable convertible preferred stock, and stockholders' deficit	$	51,825			$	54,554

 

FAQ

What were Vera Therapeutics' financial results for Q1 2021?

Vera reported a net loss of $4.7 million for Q1 2021, compared to $2.5 million in Q1 2020.

What clinical trial did Vera Therapeutics initiate recently?

Vera initiated the Phase 2b ORIGIN clinical trial of atacicept for treating IgA nephropathy.

How much capital did Vera Therapeutics raise in 2021?

Vera raised approximately $128 million over nine months, including $48.4 million from its IPO in May.

What is the current cash position of Vera Therapeutics?

As of March 31, 2021, Vera reported approximately $49.5 million in cash and cash equivalents.