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Twist Bioscience Corporation, symbol TWST, stands at the forefront of synthetic biology with an innovative approach to DNA synthesis. The company's core expertise lies in developing a proprietary semiconductor-based synthetic DNA manufacturing process. This process utilizes a unique 10,000-well silicon platform, markedly different from the traditional 96-well plastic plates. This advanced platform enables the production of synthetic biology tools, such as oligonucleotides, genes, pathways, chassis, and genomes, in a more efficient, cost-effective, and high-throughput manner.
The implications of Twist Bioscience's technology are profound, offering the potential to revolutionize various fields. By synthesizing DNA on silicon, the company overcomes existing production inefficiencies, ensuring rapid and high-quality DNA synthesis. This capability is crucial for accelerating developments in personalized medicine, sustainable chemical production, agricultural improvements, in vivo diagnostics, biodetection, and even data storage.
Based primarily in the United States, Twist Bioscience derives the majority of its revenue from its home market. The company's strategic partnerships and ongoing projects reflect its commitment to pioneering advancements in synthetic biology. Having positioned itself as a leader in the field, Twist Bioscience continues to support researchers and industries by providing high-quality synthetic DNA rapidly, enabling them to seize emerging opportunities.
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Twist Bioscience Corporation (NASDAQ: TWST) has successfully closed its public offering of 3,211,362 shares at $110.00 each, generating approximately $323.7 million in net proceeds. The offering included shares sold by both the company and certain selling stockholders. Twist plans to utilize these funds to enhance operational capacity, increase R&D investments, and expand its manufacturing capabilities for its synthetic DNA offerings. Additionally, a portion of the proceeds may be allocated towards acquiring complementary businesses.
Twist Bioscience Corporation (NASDAQ: TWST) has priced a public offering of 2,802,272 shares of common stock at $110.00 per share, aiming for approximately $300 million in gross proceeds. The offering includes 2,727,272 shares sold by Twist and 75,000 shares from selling stockholders. Expected to close on December 7, 2020, funds will enhance operational capacity, R&D, and IT infrastructure, with potential investments in complementary businesses. The offering is underwritten by J.P. Morgan, Goldman Sachs, Cowen, and Evercore.
Twist Bioscience Corporation (NASDAQ: TWST) announced its intention to conduct an underwritten public offering of up to $250 million in common stock. Additionally, certain selling stockholders plan to offer 75,000 shares. The offering includes a 30-day option for underwriters to purchase up to $37.5 million more. Twist aims to utilize net proceeds to enhance operational capacity, invest in automation and R&D, and support growth in various sectors, including NGS and DNA data storage.
Twist Bioscience Corporation (NASDAQ: TWST) announced its participation in two upcoming virtual investor conferences. Emily Leproust, CEO, and Jim Thorburn, CFO, will present at the Piper Sandler 32nd Annual Virtual Healthcare Conference on November 30 at 8:00 a.m. ET, and the Evercore ISI HealthCONx Conference on December 1 at 1:50 p.m. ET. Both presentations can be accessed on the company’s investor relations website, with replays available for 90 days post-event. Twist Bioscience specializes in synthetic DNA products and applications across multiple industries, including healthcare and agriculture.
Twist Bioscience reported strong financial results for fiscal year 2020 with total revenues increasing to $90.1 million from $54.4 million in fiscal 2019. Total orders rose to $116.7 million. Despite the growth, the company experienced a net loss of $139.9 million, or $3.57 per share. The fourth quarter also saw revenue growth to $32.4 million from $15.7 million year-over-year. With a strong cash position of $290 million, Twist plans aggressive growth in fiscal 2021, focusing on synthetic biology, NGS, and biopharma technologies.
Twist Bioscience Corporation (Nasdaq: TWST) announced promising preclinical data for three proprietary antibodies targeting the S1 protein of SARS-CoV-2. The antibodies, TB202-3 and TB202-63, demonstrated protection against weight loss in a hamster model at a low dose of 1 mg/kg. TB181-36, discovered in collaboration with Vanderbilt University, also showed protective effects at doses of 5 mg/kg and 10 mg/kg. These results suggest potential for new COVID-19 treatment approaches, including a preventive nasal spray, amid rising global infection cases.
Twist Bioscience (TWST) and Biotia have launched the SARS-CoV-2 Next-Generation Sequencing (NGS) Assay, a new research tool for COVID-19 sequencing and surveillance. This highly sensitive assay allows for extensive monitoring of the virus's genetic changes, surpassing standard PCR tests in capability. Validated on a NextSeq® sequencer, the assay provides crucial sequence data to aid researchers in tracking mutations and understanding the virus's evolution. The assay targets various sample types, offering public health insights, particularly during ongoing pandemic waves.
Twist Bioscience Corporation (NASDAQ: TWST) has launched the Comprehensive Viral Research Panel, a next-generation sequencing (NGS) tool that identifies over 3,000 viral genomes. This panel aims to assist in detecting new viral species and supports metagenomic surveillance. It features over one million unique probes and integrates with the One Codex analysis platform for streamlined results. The product is designed for research use only and contributes to public health efforts in monitoring viral diseases.
Twist Bioscience (TWST), along with Illumina (ILMN), Western Digital (WDC), and Microsoft, has formed a strategic alliance to advance DNA data storage. This coalition aims to create an industry roadmap for interoperability and commercial solutions as demand for archival storage surges due to data growth. DNA's durability and density—storing massive amounts of data in minimal space—position it as a viable alternative to traditional storage. The alliance anticipates that by 2024, 30% of digital businesses will initiate DNA storage trials, addressing the urgent need for long-term solutions.
Twist Bioscience Corporation (NASDAQ: TWST) will announce its financial results for the fiscal 2020 fourth quarter and full year on November 23, 2020, before market opening. A conference call at 8:00 a.m. ET will discuss these results and provide a business update. Investors can access the financial release via the Investor Relations section on the company's website. Twist Bioscience focuses on synthetic DNA manufacturing using a proprietary silicon platform, catering to various industries including healthcare and agriculture.