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Travere Therapeutics, Inc. - TVTX STOCK NEWS

Welcome to our dedicated page for Travere Therapeutics news (Ticker: TVTX), a resource for investors and traders seeking the latest updates and insights on Travere Therapeutics stock.

Travere Therapeutics, Inc. (NASDAQ: TVTX) is a biopharmaceutical company dedicated to identifying, developing, and delivering life-changing therapies for people living with rare kidney, liver, and metabolic diseases. The company's key focus is the development of its investigational product candidate, sparsentan. This novel therapy is in late-stage development for treating focal segmental glomerulosclerosis (FSGS) and IgA nephropathy (IgAN), both rare kidney disorders that can lead to end-stage kidney disease.

Travere Therapeutics has made significant strides in its mission, marked by several recent achievements. The company reported positive topline data from the pivotal phase-III PROTECT study of sparsentan in IgAN, showing a substantial reduction in proteinuria and potential long-term benefits in preserving kidney function. This led to the conditional marketing authorization of sparsentan under the brand name FILSPARI® in Europe and anticipated full approval in the U.S.

Additionally, Travere Therapeutics is advancing other innovative therapies. The company is exploring the potential of pegtibatinase as the first disease-modifying treatment for classical homocystinuria (HCU), with topline data expected in 2026.

Travere's strategic partnerships, such as with CSL Vifor, amplify its reach and impact. CSL Vifor has exclusive commercialization rights for sparsentan in Europe, Australia, and New Zealand. Together, these companies are dedicated to bringing promising treatments to patients worldwide.

The company's financial condition remains robust, supported by a strong pipeline and successful trials. Travere's commitment to the rare disease community is evidenced by its relentless pursuit of better treatment options and its collaborative efforts with patients, families, and caregivers.

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Travere Therapeutics, Inc. (Nasdaq: TVTX) has opened enrollment in the HARMONY Study, a global, randomized pivotal Phase 3 clinical trial of pegtibatinase, an investigational enzyme replacement therapy for classical homocystinuria (HCU). The study aims to determine the safety and efficacy of pegtibatinase in reducing plasma total homocysteine (tHcy) levels, with topline data expected in 2026.
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Travere Therapeutics, Inc. (Nasdaq: TVTX) plans to submit a supplemental New Drug Application (sNDA) to FDA in Q1 2024 for conversion of the existing U.S. accelerated approval of FILSPARI® (sparsentan) in IgAN to full approval. The company is also implementing strategic reorganization to focus resources on ongoing FILSPARI launch in IgAN and advancement of pegtibatinase in classical HCU, extending expected cash runway into 2028.
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Travere Therapeutics, Inc. (TVTX) to present at 6th Annual Evercore ISI HealthCONx Conference on November 28, 2023
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Travere Therapeutics, Inc. (NASDAQ: TVTX) reported $8 million in net product sales for FILSPARI® (sparsentan) in the third quarter of 2023. The company received 430 new patient start forms and completed the sale of its bile acid product portfolio for up to $445 million.
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Travere Therapeutics announced positive results from two Phase 3 studies of sparsentan in treating IgA nephropathy (IgAN) and focal segmental glomerulosclerosis (FSGS). The studies showed that sparsentan has the potential to preserve kidney function and significantly delay time to kidney failure compared to an active comparator. Sparsentan demonstrated consistent treatment effects, higher rates of remission, and lower rates of end-stage kidney disease. The drug was well-tolerated with a safety profile comparable to the active comparator.
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Travere Therapeutics, Inc. (NASDAQ: TVTX) will report Q3 2023 financial results on November 7, 2023, and host a conference call to discuss the results and provide a business update.
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Travere Therapeutics to present 11 abstracts at ASN Kidney Week 2023
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Travere Therapeutics grants inducement equity grants to new employees
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Travere Therapeutics to present preliminary findings from the SPARTAN Study on FILSPARI as a first-line therapy for IgA nephropathy at IIGANN2023. 24-week data on proteinuria reduction, blood pressure control, and safety will be presented. Preclinical data supports the nephroprotective mechanism of action of sparsentan. Patients with IgAN considered 'low-risk' had high rates of kidney failure.
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Travere Therapeutics announces positive results from Phase 3 PROTECT Study of FILSPARI in IgA nephropathy (IgAN) vs. irbesartan. FILSPARI demonstrated long-term kidney function preservation and achieved a clinically meaningful difference in eGFR total and chronic slope. FILSPARI to submit sNDA for full approval in the U.S. in 1H 2024.
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FAQ

What is the current stock price of Travere Therapeutics (TVTX)?

The current stock price of Travere Therapeutics (TVTX) is $18.26 as of November 21, 2024.

What is the market cap of Travere Therapeutics (TVTX)?

The market cap of Travere Therapeutics (TVTX) is approximately 1.6B.

What is the primary focus of Travere Therapeutics?

Travere Therapeutics focuses on developing therapies for rare kidney, liver, and metabolic diseases.

What is sparsentan?

Sparsentan is an investigational product candidate being developed by Travere Therapeutics for treating FSGS and IgAN.

What recent achievements has Travere Therapeutics made?

Travere Therapeutics has reported positive topline data from the phase-III PROTECT study of sparsentan in IgAN and received conditional marketing authorization for sparsentan in Europe.

What are the indications for FILSPARI®?

FILSPARI® is indicated for reducing proteinuria in adults with primary IgA nephropathy at risk of rapid disease progression.

Who are Travere Therapeutics' strategic partners?

CSL Vifor is a key strategic partner, holding exclusive commercialization rights for sparsentan in Europe, Australia, and New Zealand.

What is the potential significance of pegtibatinase?

Pegtibatinase has the potential to become the first disease-modifying treatment for classical homocystinuria, with topline data expected in 2026.

What are the key safety considerations for FILSPARI® therapy?

Safety considerations include monitoring for hepatotoxicity and embryo-fetal toxicity; the therapy is available only through a restricted program called the FILSPARI REMS.

What is the financial condition of Travere Therapeutics?

Travere Therapeutics maintains a robust financial condition supported by a strong pipeline and successful clinical trials.

How does Travere Therapeutics develop its therapies?

Travere collaborates closely with the rare disease community to understand their needs and develops life-changing therapies based on these insights.

Where can more information about Travere Therapeutics be found?

More information can be found on their official website, travere.com.

Travere Therapeutics, Inc.

Nasdaq:TVTX

TVTX Rankings

TVTX Stock Data

1.59B
77.32M
0.65%
98.57%
10.24%
Biotechnology
Pharmaceutical Preparations
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United States of America
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