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2Seventy Bio - TSVT STOCK NEWS

Welcome to our dedicated page for 2Seventy Bio news (Ticker: TSVT), a resource for investors and traders seeking the latest updates and insights on 2Seventy Bio stock.

2Seventy Bio Inc (TSVT) is a clinical-stage biotechnology company pioneering cell therapies for cancer treatment through innovative immuno-oncology research. This dedicated news hub provides investors and medical professionals with essential updates on the company’s scientific advancements and corporate developments.

Access real-time updates on clinical trial progress, regulatory milestones, and strategic partnerships shaping 2Seventy Bio’s pipeline of cellular therapies. Our curated collection includes earnings reports, research publications, and management commentary – all organized for efficient tracking of this precision medicine innovator.

Key coverage areas include novel therapy approvals, collaborative research initiatives with leading institutions, and analyses of the company’s position within the competitive cell & gene editing landscape. All content undergoes rigorous verification to ensure compliance with financial disclosure standards.

Bookmark this page for streamlined access to TSVT’s latest developments in cancer treatment innovation. Combine our news monitoring with Stock Titan’s analytical tools to maintain informed perspectives on this dynamic biotech enterprise.

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2seventy bio (NASDAQ: TSVT) announced promising preclinical data for bbT369, a novel CAR T cell therapy targeting CD79a and CD20, showing enhanced efficacy against B cell non-Hodgkin lymphoma (B-NHL). bbT369 aims to address limitations of existing CAR T therapies by overcoming known mechanisms of treatment failure. Currently, the CRC-403 Phase 1/2 study is enrolling patients to assess its safety and efficacy, with initial results expected in 2022. This innovative approach could offer new hope for patients with relapsed or refractory B-NHL.

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2seventy bio (Nasdaq: TSVT) will present at the CG Horizons in Oncology Virtual Conference on April 14, 2022, at 1:30 PM ET. The focus will be on new approaches to attacking AML. Live webcasts of the presentations will be accessible in the Investors and Media section of the company's website, with replays available for 30 days afterward. 2seventy bio aims to revolutionize cancer therapies through innovative cell treatments, emphasizing speed and efficacy in research and development.

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2seventy bio (Nasdaq: TSVT) closed a $170 million private placement and reported 2021 financial results, with ABECMA generating $158 million in U.S. revenue. The company anticipates 2022 U.S. ABECMA revenues of $250-$300 million, tracking towards the high end due to strong patient demand. Cost reduction measures decreased net cash spend guidance to $190-$220 million for 2022, extending cash runway into 2025.

Positive developments include increased ABECMA manufacturing capacity planned for 2022, and key management appointments to drive growth.

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2seventy bio, Inc. (NASDAQ: TSVT) has announced a private placement sale of approximately 13.9 million shares at $12.20 per share, raising around $170 million. The financing, closing on March 17, 2022, will bolster the company's cash runway through 2025, supporting its ongoing research, development, and commercialization of ABECMA. With a cash reserve of $362.2 million at the end of 2021, combined with a decrease in net cash spend to $190-$220 million, the company is positioned for critical upcoming milestones.

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2seventy bio, Inc. (NASDAQ: TSVT) announced key leadership appointments, welcoming Steven Bernstein, M.D. as chief medical officer and promoting Susan Abu-Absi, Ph.D. to chief technology & manufacturing officer. Dr. Bernstein brings over 25 years of experience in oncology and translational science, while Dr. Abu-Absi has a solid background in cell and gene therapy development. The company aims to enhance its cell therapy product engine, focusing on transformative treatments for cancer patients.

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2seventy bio (NASDAQ: TSVT) announced its participation in two upcoming investor conferences. The first is the SVB Leerink 10th Annual Global Healthcare Conference on February 16, 2022, at 2:20pm ET, featuring a fireside chat. The second event is the Cowen Virtual 42nd Annual Healthcare Conference on March 7, 2022, at 12:50pm ET, where the company will discuss "Novel Oncology Targets." Live webcasts will be available on 2seventy bio's website, with replays archived for 30 days.

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2seventy bio provided a strong outlook for 2022, predicting $250-300M in U.S. revenue from its CAR-T product ABECMA, which has generated $150M in 2021. The company ended 2021 with approximately $360M in cash, expecting a reduced net cash spend of $220-250M in 2022. The FDA has cleared the IND for bbT369 targeting B-cell non-Hodgkin lymphoma, and a new solid tumor CAR-T program targeting MUC16 was unveiled, reflecting ongoing innovation in their pipeline.

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2seventy bio has entered an option and license agreement with Novo Nordisk for developing an in vivo gene editing treatment for hemophilia A, leveraging its megaTAL™ technology. The agreement includes an upfront payment of $5 million and eligible future payments totaling $40 million. Additionally, 2seventy bio has partnered with Genevant Sciences to utilize its lipid nanoparticle technology for mRNA delivery. This collaboration is seen as a significant expansion of 2seventy bio's oncology pipeline.

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2seventy bio (NASDAQ: TSVT) announced new clinical data from its oncology cell therapy portfolio at the American Society of Hematology Annual Meeting. Key highlights include updates from the Phase 1 CRB-402 study of bb21217 for multiple myeloma and analyses from the pivotal KarMMa study of ABECMA, the first CAR T cell therapy for this condition. Patients treated with ABECMA showed improved quality of life and durable responses, with 69% overall response rates and a 23.8-month median duration of response. Preclinical data for SC-DARIC33 were also presented, indicating its potential to treat pediatric AML.

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2seventy bio (Nasdaq: TSVT) reported its Q3 2021 financial results, posting total revenues of $19.3 million, a slight increase from $18.4 million in Q3 2020. The company has accepted its first IND for SC-DARIC33 to treat acute myeloid leukemia, now enrolling patients in a Phase 1 study. Research and development expenses decreased to $61.1 million from $72.3 million year-over-year. Despite a net loss of $60 million, 2seventy remains optimistic about its pipeline and partnerships, particularly with Bristol Myers Squibb for ABECMA, which generated $67 million in revenue.

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Nasdaq:TSVT

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260.65M
48.67M
6.59%
85.1%
9.31%
Biotechnology
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