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Therapeutic Solutions International Spin-Off Campbell Neurosciences Identifies Mechanism of Action for Umbilical Cord Blood Derived NarcoStem™ Drug Rehabilitation Product

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Therapeutic Solutions International (OTC: TSOI) announced significant findings regarding NarcoStem™, a biologic derived from umbilical cord blood, showcasing its role in stimulating Brain Derived Neurotrophic Factor (BDNF) production. This advancement is crucial for treating drug addiction and repairing brain damage. The company emphasizes the importance of BDNF in combating addiction and improving mental health. Positive preliminary data supports the efficacy of NarcoStem™ in addressing neurological issues, especially in post-COVID patients. The ongoing collaboration with Campbell Neurosciences aims to accelerate therapeutic development.

Positive
  • Identification of BDNF's role in the efficacy of NarcoStem™ supports its potential as a breakthrough treatment for addiction.
  • Preliminary data indicates NarcoStem™ can stimulate the brain to produce its own BDNF, enhancing therapeutic effectiveness.
  • Positive clinical data regarding Campbell Score and Kaihani Score suggests promising future applications in mental health treatments.
Negative
  • None.

ELK CITY, Idaho, April 19, 2021 /PRNewswire/ -- Therapeutic Solutions International, Inc., (OTC Markets: TSOI), announced today data implicating a key role in the protein Brain Derived Neurotrophic Factor (BDNF) in the therapeutic activities of NarcoStem™, an umbilical cord blood derived biologic demonstrated to possess positive animal data in preclinical models of addiction and drug induced brain damaged.

"It is saddening that what many consider to be cutting edge approaches to treatment of drug addiction is simply replacement of one harmful drug with another drug," stated Dr. James Veltmeyer, Chief Medical Officer of Therapeutic Solutions International and Top Doctor of San Diego. "I am proud to work with TSOI and with Campbell Neurosciences at creating a therapy that concurrently reduces brain inflammation, suppresses addiction associated urges, while at the same time repairs damaged nerve tissue. This is not something that ketamine, CBD, or psilocybin are capable of doing.  Demonstration that BDNF mediates therapeutic activities of NarcoStem™ helps accelerate the timeline for clinical translation of this inhalable therapeutic."

BDNF is considered a "master molecule" in controlling brain function and has been reported by numerous groups to associate with efficacy of anti-depressants, as well as the ability to overcome addictive tendencies.  Unfortunately, it is almost impossible to provide recombinant BDNF directly into the brain due to its size and half live.  Accordingly, preliminary data by the Company suggests that administration of NarcoStem™ can directly stimulate the brain to produce its own BDNF.

"The recent successes in obtaining positive clinical data for both the Campbell Score and the Kaihani Score pushes us to initiate creation of therapeutic approaches to actually intervene at suicidal ideations and conditions predisposing to these conditions," said Kalina O'Connor, President and CEO of Campbell Neurosciences. "It is fundamentally important that we know the mechanisms of action for our products and we are extremely satisfied at the "Warp Speed" that our scientists have been working on to generate this exciting data."

"The staggering rise in drug addiction, as well as the disturbing news that as many as 1 out of 3 post-covid patients will suffer neurological manifestations, is very strong rationale for our 'hyper-acceleration,' in developing regenerative approaches to neurological issues," said Timothy Dixon, President and CEO of TSOI. "We look forward to continuing our collaborations with internationally renowned scientists dedicated to utilizing modern day approaches to solve this age-old curse of drug addiction." 

About Therapeutic Solutions International, Inc.
Therapeutic Solutions International is focused on immune modulation for the treatment of several specific diseases. The Company's corporate website is www.therapeuticsolutionsint.com, and our public forum is https://board.therapeuticsolutionsint.com/ 

ir@tsoimail.com

 

Cision View original content:http://www.prnewswire.com/news-releases/therapeutic-solutions-international-spin-off-campbell-neurosciences-identifies-mechanism-of-action-for-umbilical-cord-blood-derived-narcostem-drug-rehabilitation-product-301271379.html

SOURCE Therapeutic Solutions International

FAQ

What is the significance of BDNF in Therapeutic Solutions International's NarcoStem™?

BDNF is crucial for brain function and is linked to anti-depressant efficacy and overcoming addiction, highlighting NarcoStem™'s therapeutic potential.

How does NarcoStem™ aim to address drug addiction?

NarcoStem™ is designed to reduce brain inflammation and suppress addiction-related urges while repairing damaged nerve tissue.

What preliminary results have been reported for NarcoStem™?

Preliminary results show that NarcoStem™ may effectively stimulate the brain's production of BDNF, offering a new approach for treating addiction-related issues.

Who is involved in the development of NarcoStem™?

Therapeutic Solutions International collaborates with Campbell Neurosciences to advance NarcoStem™'s therapeutic applications.

What recent trends in drug addiction have prompted TSOI's renewed focus on treatment?

The surge in drug addiction rates and the neurological impacts of COVID-19 have spurred TSOI to accelerate the development of regenerative therapies.

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