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Tourmaline Bio, Inc. (TRML) is a late-stage clinical biotechnology company dedicated to developing groundbreaking medicines for patients with severe immune diseases. Headquartered in Boston, MA, and Louisville, KY, Tourmaline Bio is at the forefront of biotechnological advancements with a focus on transformative cell therapies. The company's mission is to significantly enhance patients' lives by offering treatments that can potentially eradicate the need for chronic immunosuppression in organ transplant recipients and induce lasting remissions in individuals with severe autoimmune and immune-mediated disorders.
The centerpiece of Tourmaline Bio's innovation is TOUR006, a fully human monoclonal antibody that targets interleukin-6 (IL-6), a crucial proinflammatory cytokine implicated in numerous autoimmune and inflammatory diseases. The IL-6 antibody class, including anti-IL-6 and anti-IL-6 receptor (IL-6R) antibodies, has a proven track record spanning over two decades, serving more than a million patients globally. TOUR006 harnesses this extensive clinical and commercial experience to offer potential new treatments for life-altering conditions.
Founded on pioneering technology developed by Dr. Suzanne Ildstad, Tourmaline Bio operates its own state-of-the-art cell processing facility in Louisville. The company is backed by top-tier life sciences investors such as Blackstone Life Sciences, Longitude Capital, and Qiming Venture Partners USA, underscoring its robust financial foundation.
Tourmaline Bio is committed to advancing its clinical programs and is currently navigating the complex pathways of regulatory approvals and clinical trials. Despite the inherent uncertainties and potential delays in the biotech sector, the company remains steadfast in its vision. Tourmaline Bio continually engages in forward-looking statements, understanding the risks and challenges ahead, including the need for substantial additional capital and achieving successful clinical outcomes.
For the latest updates and developments, investors and stakeholders can refer to Tourmaline Bio's periodic filings with the Securities and Exchange Commission (SEC), including the detailed 'Risk Factors' section in the Quarterly Report on Form 10-Q for the quarter ended September 30, 2023.
Tourmaline Bio announced the promotion of Ryan Robinson, CPA, to Chief Financial Officer and Treasurer, effective June 25, 2024. Robinson has been with Tourmaline since last summer and has served as the Interim CFO and Treasurer since October 2023. He played a key role in Tourmaline's growth, including a reverse merger in October 2023 and a $172.5 million public offering in January 2024. Robinson brings nearly 15 years of biotech finance and operations experience, having worked at Korro Bio, Jounce Therapeutics, and Merrimack Pharmaceuticals. He holds a B.S. in Management and an M.S. in Accounting from Boston College and is a CPA.
Tourmaline Bio (NASDAQ: TRML), a late-stage clinical biotechnology company, announced that its CEO, Sandeep Kulkarni, will present at the Jefferies Global Healthcare Conference in New York. The presentation is scheduled for Thursday, June 6, 2024, at 2:30 pm ET. A live webcast and replay will be available on the Tourmaline Bio website.
Tourmaline Bio has dosed the first patient in its Phase 2 TRANQUILITY trial for TOUR006, a monoclonal antibody targeting IL-6 to treat atherosclerotic cardiovascular disease (ASCVD) and other cardiovascular conditions. This randomized, double-blind, placebo-controlled trial involves patients with high inflammatory risk and chronic kidney disease. The trial aims to assess the drug's safety, pharmacokinetics, and pharmacodynamics, with results anticipated in the first half of 2025. If successful, TOUR006 could advance to Phase 3 by 2025, offering quarterly subcutaneous dosing and potentially positioning itself as a best-in-class treatment for ASCVD and related conditions.
Tourmaline Bio, Inc. reported its Q1 2024 financial results and recent business highlights. Initiatives include a Phase 2 trial for ASCVD and TED, a successful public offering, and $350.3 million in cash reserves. The company aims to improve the lives of patients with immune and inflammatory diseases.
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