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Entrada Therapeutics, Inc. - TRDA STOCK NEWS

Welcome to our dedicated page for Entrada Therapeutics news (Ticker: TRDA), a resource for investors and traders seeking the latest updates and insights on Entrada Therapeutics stock.

Entrada Therapeutics, Inc. (Nasdaq: TRDA) is a clinical-stage biopharmaceutical company dedicated to transforming the lives of patients by developing a new class of medicines known as Endosomal Escape Vehicle (EEV™)-therapeutics. Founded in 2016 by 5AM Ventures, Entrada aims to make previously inaccessible intracellular targets reachable, thereby opening new avenues for treating serious diseases.

Entrada Therapeutics is pioneering the delivery of a wide range of therapeutics to various organs and tissues, thereby improving the therapeutic index. The company's portfolio includes programs targeting neuromuscular diseases, immunological disorders, and metabolic conditions, amongst others.

One of the company's most promising candidates is ENTR-601-44, which is being developed to treat Duchenne muscular dystrophy (DMD), particularly in patients who are exon 44 skipping amenable. The ongoing Phase 1 clinical trial for ENTR-601-44 aims to evaluate the safety, tolerability, pharmacokinetics, and target engagement in healthy volunteers. This trial has already enrolled its first participants, with data anticipated in the second half of 2024.

Recent Achievements:In recent news, Entrada Therapeutics received authorization from the United Kingdom's Medicines and Healthcare Products Regulatory Agency (MHRA) and the Research Ethics Committee (REC) to conduct its Phase 1 clinical trial of ENTR-601-44. Additionally, the company reported robust financial results for the third quarter of 2023, with significant cash reserves and collaboration revenue marking crucial steps in their growth trajectory.

Strategic Milestones:Entrada Therapeutics is well-positioned to continue its strategic initiatives through 2025, thanks to its strong financial footing and ongoing collaborations. The company has also recently appointed Nathan J. Dowden as President and Chief Operating Officer, further strengthening its executive team.

Beyond its lead program, Entrada's pipeline includes several other candidates aimed at treating various subtypes of DMD and myotonic dystrophy type 1 (DM1). These developments underscore Entrada's commitment to advancing its modular EEV platform to address a broad spectrum of unmet medical needs.

For more detailed and up-to-date information about Entrada Therapeutics, please visit their official website and follow them on LinkedIn.

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Entrada Therapeutics, Inc. (Nasdaq: TRDA) announced its second clinical candidate, ENTR-701, aimed at treating myotonic dystrophy type 1. The company is on track to submit an Investigational New Drug application for ENTR-601-44, targeting Duchenne muscular dystrophy, in Q4 2022. As of March 31, 2022, Entrada has $263.9 million in cash and equivalents, projecting sufficient funds to support operations into the second half of 2024. However, the first quarter of 2022 reported a net loss of $21.7 million, significantly higher than the $8.4 million loss in Q1 2021.

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Entrada Therapeutics (Nasdaq: TRDA) has shared promising non-human primate data for its lead candidate, ENTR-601-44, indicating a durability of response for 12 weeks in treating Duchenne muscular dystrophy (DMD). The company also introduced ENTR-701, targeted at myotonic dystrophy type 1 (DM1). Both candidates are set for Investigational New Drug applications: ENTR-601-44 in Q4 2022 and ENTR-701 in 2023. These advancements reinforce Entrada's commitment to developing intracellular therapeutics with potential for transformative patient outcomes.

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Entrada Therapeutics (Nasdaq: TRDA) announced that CEO Dipal Doshi will present virtually at the H.C. Wainwright Global Investment Conference from May 23-26, 2022. The presentation will be accessible starting May 23, 2022, at 7:00 a.m. ET on the company's website. A replay will be available for 90 days after the event.

Entrada focuses on Endosomal Escape Vehicle (EEV™) therapeutics to deliver medicines intracellularly, particularly for conditions like Duchenne muscular dystrophy and myotonic dystrophy.

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Entrada Therapeutics (Nasdaq: TRDA) reported financial results for the fourth quarter and full year ending December 31, 2021. The company secured approximately $209 million from its IPO and held $291.1 million in cash as of year-end. Planned developments include submitting an IND application for ENTR-601-44 targeting Duchenne muscular dystrophy in the second half of 2022. R&D expenses rose to $12.4 million for Q4 2021, with a net loss of $18.4 million. G&A expenses also increased significantly, reflecting higher personnel and professional fees.

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Entrada Therapeutics (Nasdaq: TRDA) will have its CEO, Dipal Doshi, participate in the Neuromuscular Panel at the Cowen 42nd Annual Health Care Conference on March 7, 2022, at 9:10 a.m. ET. The event aims to discuss the company’s innovative therapeutics, specifically its Endosomal Escape Vehicle (EEV™) technology. A live webcast will be available on Entrada’s website, with a replay accessible for 90 days post-event. The company focuses on developing treatments for neuromuscular diseases and has a robust portfolio targeting conditions like Duchenne muscular dystrophy.

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Entrada Therapeutics (Nasdaq: TRDA) has appointed Jared Cohen, PhD, JD, as General Counsel, effective immediately. This move is a recognition of his significant contributions since joining the company, particularly in legal and compliance functions during recent financings. Dr. Cohen, who has nearly 20 years of experience in the healthcare sector, previously held leadership positions at several biopharmaceutical organizations. His appointment is expected to guide Entrada through its next phase of growth in developing its innovative Endosomal Escape Vehicle (EEV™) therapeutics.

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Entrada Therapeutics (Nasdaq: TRDA) announced its addition to the Russell 2000® and Russell 3000® Indexes, effective December 20, 2021. This inclusion follows the company's successful IPO in November 2021 and aims to enhance market awareness for its Endosomal Escape Vehicle (EEV™) therapeutics. The Russell indexes are benchmarks for investment strategies, with about $10.7 trillion in assets linked to them. This milestone is expected to broaden Entrada's visibility in the investment community, as it advances its EEV therapeutic candidates targeting previously inaccessible intracellular targets.

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Entrada Therapeutics, Inc. (Nasdaq: TRDA) completed a successful upsized IPO, raising $208.7 million in November 2021, positioning the company for significant advancements. Financial results for Q3 2021 revealed cash and cash equivalents of $122.2 million, excluding IPO proceeds. R&D expenses rose to $10.5 million, driven by preclinical studies and higher personnel costs. G&A expenses also increased to $3.9 million, reflecting higher legal fees and personnel costs. The net loss for Q3 2021 was $14.4 million, compared to $7.0 million in Q3 2020, signaling increased operational investments.

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Entrada Therapeutics (Nasdaq: TRDA) announced that CEO Dipal Doshi will participate in a fireside chat at the Evercore ISI 4th Annual HealthCONx Virtual Conference on December 2, 2021, at 12:10 p.m. ET. The event aims to showcase Entrada's focus on creating Endosomal Escape Vehicle (EEV™) therapeutics to tackle previously unaddressed intracellular targets. A live webcast of the chat will be available on the company's website, followed by a 90-day replay. Entrada is developing EEV therapeutics to enhance treatment for various diseases, including Duchenne muscular dystrophy.

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Entrada Therapeutics, Inc. (Nasdaq: TRDA) announced the closing of its initial public offering, successfully selling 9,075,000 shares at $20.00 each, raising approximately $181.5 million. All shares were offered by Entrada. The offering commenced trading on October 29, 2021. Underwriters also hold an option for an additional 1,361,250 shares within 30 days. Goldman Sachs, Cowen, and Evercore acted as joint book-running managers for this offering. The company focuses on innovative Endosomal Escape Vehicle (EEV™) therapeutics targeting previously inaccessible intracellular diseases.

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FAQ

What is the current stock price of Entrada Therapeutics (TRDA)?

The current stock price of Entrada Therapeutics (TRDA) is $17.59 as of December 20, 2024.

What is the market cap of Entrada Therapeutics (TRDA)?

The market cap of Entrada Therapeutics (TRDA) is approximately 646.2M.

What is Entrada Therapeutics' core business?

Entrada Therapeutics is focused on developing intracellular biologics to treat serious diseases using their Endosomal Escape Vehicle (EEV™)-therapeutics platform.

What is ENTR-601-44?

ENTR-601-44 is a lead product candidate for treating Duchenne muscular dystrophy (DMD) in patients amenable to exon 44 skipping.

What recent milestones has Entrada Therapeutics achieved?

Recently, Entrada received MHRA authorization for a Phase 1 trial of ENTR-601-44 and reported strong third-quarter financial results.

What is the aim of the ongoing clinical trial for ENTR-601-44?

The Phase 1 clinical trial aims to evaluate the safety, tolerability, pharmacokinetics, and target engagement of ENTR-601-44 in healthy volunteers.

Who founded Entrada Therapeutics?

Entrada Therapeutics was co-founded in 2016 by 5AM Ventures, a prominent life sciences venture capital firm.

What diseases does Entrada Therapeutics aim to treat?

Entrada targets a range of diseases including neuromuscular, immunological, ocular, and metabolic disorders.

How is Entrada Therapeutics funded?

Entrada is funded through various means, including cash reserves, marketable securities, and collaboration revenues.

Who is the current CEO of Entrada Therapeutics?

Dipal Doshi is the President and Chief Executive Officer of Entrada Therapeutics.

Where can I find more information about Entrada Therapeutics?

You can find more information on their official website at www.entradatx.com and their LinkedIn page.

What is the significance of the EEV™ platform?

The EEV™ platform enables the efficient delivery of a wide range of therapeutics into various organs and tissues, improving the therapeutic index.

Entrada Therapeutics, Inc.

Nasdaq:TRDA

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646.24M
31.89M
12.77%
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4.3%
Biotechnology
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