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Tempest Announces Amezalpat Poster Presentation at the 2025 American Association for Cancer Research (AACR) Annual Meeting

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Tempest Therapeutics (NASDAQ: TPST) has announced that data supporting the immune component of amezalpat's mechanism of action will be presented at the 2025 American Association for Cancer Research (AACR) Annual Meeting. The presentation, which will be in poster format, is scheduled to take place during the conference running from April 25-30, 2025 in Chicago, IL. The abstract highlights clinical data that reinforces amezalpat's potential as a novel cancer treatment.

Tempest Therapeutics (NASDAQ: TPST) ha annunciato che i dati a supporto della componente immunitaria del meccanismo d'azione di amezalpat saranno presentati al 2025 American Association for Cancer Research (AACR) Annual Meeting. La presentazione, che sarà in formato poster, è programmata per svolgersi durante la conferenza che si terrà dal 25 al 30 aprile 2025 a Chicago, IL. L'abstract evidenzia dati clinici che rafforzano il potenziale di amezalpat come nuovo trattamento per il cancro.

Tempest Therapeutics (NASDAQ: TPST) ha anunciado que se presentarán datos que respaldan el componente inmunológico del mecanismo de acción de amezalpat en la Reunión Anual de la Asociación Americana para la Investigación del Cáncer (AACR) de 2025. La presentación, que será en formato de póster, está programada para llevarse a cabo durante la conferencia que se celebrará del 25 al 30 de abril de 2025 en Chicago, IL. El resumen destaca datos clínicos que refuerzan el potencial de amezalpat como un nuevo tratamiento contra el cáncer.

템페스트 테라퓨틱스 (NASDAQ: TPST)아메잘파트의 작용 메커니즘의 면역 구성 요소를 지원하는 데이터가 2025 미국 암 연구 협회 (AACR) 연례 회의에서 발표될 것이라고 발표했습니다. 포스터 형식으로 진행될 이 발표는 2025년 4월 25일부터 30일까지 일리노이주 시카고에서 열리는 회의 중에 진행될 예정입니다. 초록은 아메잘파트가 새로운 암 치료제로서의 잠재력을 강화하는 임상 데이터를 강조합니다.

Tempest Therapeutics (NASDAQ: TPST) a annoncé que des données soutenant la composante immunitaire du mécanisme d'action de amezalpat seront présentées lors de la Réunion Annuelle de l'Association Américaine pour la Recherche sur le Cancer (AACR) de 2025. La présentation, qui se fera sous forme de poster, est prévue pendant la conférence qui se déroulera du 25 au 30 avril 2025 à Chicago, IL. Le résumé met en avant des données cliniques qui renforcent le potentiel d'amezalpat en tant que nouveau traitement contre le cancer.

Tempest Therapeutics (NASDAQ: TPST) hat angekündigt, dass Daten, die die immunologische Komponente des Wirkmechanismus von amezalpat unterstützen, auf dem 2025 American Association for Cancer Research (AACR) Annual Meeting präsentiert werden. Die Präsentation, die im Posterformat stattfinden wird, ist für die Konferenz vom 25. bis 30. April 2025 in Chicago, IL, geplant. Das Abstract hebt klinische Daten hervor, die das Potenzial von amezalpat als neuartige Krebsbehandlung untermauern.

Positive
  • Acceptance of clinical data presentation at major cancer research conference (AACR)
Negative
  • None.

Clinical data supporting mechanism of action reinforce potential as a novel cancer treatment

BRISBANE, Calif., March 25, 2025 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, today announced that an abstract highlighting data supporting the immune component of amezalpat’s purported mechanism of action has been accepted for poster presentation at the 2025 American Association for Cancer Research (AACR) Annual Meeting taking place April 25-30, 2025 in Chicago, IL.

Poster presentation details:

Title:Amezalpat, a peroxisome proliferator-activated receptor alpha (PPARα) antagonist, inhibits suppressive macrophage development, activation and function
Abstract Number:2171
Date & Time:Monday, April 28, 2025, 9:00 a.m. – 12:00 p.m. CT
Session Category:Immunology
Session Title:Interplay between Immune System and Radio-, Chemo- and Targeted Therapies 1
Location:Poster Section 35
  

All regular abstracts are available for viewing via AACR’s online itinerary planner located, here.

About Tempest Therapeutics

Tempest Therapeutics is a clinical-stage biotechnology company advancing a diverse portfolio of small molecule product candidates containing tumor-targeted and/or immune-mediated mechanisms with the potential to treat a wide range of tumors. The company’s novel programs range from early research to later-stage investigation in a randomized global study in first-line cancer patients. Tempest is headquartered in Brisbane, California. More information about Tempest can be found on the company’s website at www.tempesttx.com.

Forward-Looking Statements

This press release contains forward-looking statements (including within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended (the “Securities Act”)) concerning Tempest Therapeutics, Inc. These statements may discuss goals, intentions, and expectations as to future plans, trends, events, results of operations or financial condition, or otherwise, based on current beliefs of the management of Tempest Therapeutics, as well as assumptions made by, and information currently available to, management of Tempest Therapeutics. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as “may,” “will,” “should,” “would,” “could”, “expect,” “anticipate,” “plan,” “likely,” “believe,” “estimate,” “project,” “intend,” and other similar expressions. All statements that are not historical facts are forward-looking statements, including any statements regarding: the design, initiation, progress, timing, scope and results of clinical trials, including the anticipated Phase 3 study for amezalpat; anticipated therapeutic benefit and regulatory development of the Company’s product candidates the Company’s ability to advance into a late-stage clinical company; and the Company’s ability to achieve its operational plans. Forward-looking statements are based on information available to Tempest Therapeutics as of the date hereof and are not guarantees of future performance. Any factors may cause differences between current expectations and actual results, including: unexpected safety or efficacy data observed during preclinical or clinical trials; clinical trial site activation or enrollment rates that are lower than expected; changes in expected or existing competition; changes in the regulatory environment; and unexpected litigation or other disputes. Other factors that may cause actual results to differ from those expressed or implied are discussed in greater detail in the “Risk Factors” section of the Company’s Quarterly Report on Form 10-Q filed for the quarter ended September 30, 2024 and other documents filed by the Company from time to time with the Securities and Exchange Commission. Except as required by applicable law, Tempest Therapeutics undertakes no obligation to revise or update any forward-looking statement, or to make any other forward-looking statements, whether as a result of new information, future events or otherwise. These forward-looking statements should not be relied upon as representing Tempest Therapeutics’ views as of any date subsequent to the date of this press release and should not be relied upon as prediction of future events. In light of the foregoing, investors are urged not to rely on any forward-looking statement in reaching any conclusion or making any investment decision about any securities of Tempest Therapeutics.

Investor & Media Contacts:

Sylvia Wheeler
Wheelhouse Life Science Advisors
swheeler@wheelhouselsa.com

Aljanae Reynolds
Wheelhouse Life Science Advisors
areynolds@wheelhouselsa.com


i If approved by the FDA


FAQ

What will Tempest Therapeutics (TPST) present at the 2025 AACR Annual Meeting?

TPST will present clinical data supporting the immune component of amezalpat's mechanism of action as a potential novel cancer treatment in a poster presentation.

When and where will TPST's amezalpat data be presented at AACR 2025?

The presentation will take place during the AACR Annual Meeting from April 25-30, 2025, in Chicago, IL.

What is the significance of TPST's amezalpat presentation at AACR 2025?

The presentation reinforces amezalpat's potential as a first-in-class targeted and immune-mediated therapeutic for cancer treatment.

How can investors access TPST's amezalpat abstract for AACR 2025?

The abstract is available for viewing through AACR's online itinerary planner.
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