Theseus Pharmaceuticals Appoints Steven Stein, M.D. to Board of Directors

Rhea-AI Summary

Theseus Pharmaceuticals (NASDAQ: THRX) announced the appointment of Dr. Steven Stein to its Board of Directors. This strategic leadership move aims to enhance the company's development of its therapeutic programs, particularly THE-630 and THE-349, targeting advanced cancer treatments. Dr. Stein, currently Chief Medical Officer at Incyte, brings extensive oncology expertise. His track record in clinical development is expected to be invaluable as Theseus advances its precision oncology initiatives.

Positive

• Appointment of Dr. Steven Stein enhances board expertise in oncology.
• Dr. Stein's experience in clinical development may accelerate product pipelines.
• Focus on advancing THE-630 and THE-349 programs could strengthen market position.

Negative

• None.

CAMBRIDGE, Mass., Oct. 19, 2022 /PRNewswire/ -- Theseus Pharmaceuticals, Inc. (NASDAQ: THRX) (Theseus or the Company), a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients through the discovery, development, and commercialization of transformative targeted therapies, today announced the appointment of Steven Stein, M.D. to its Board of Directors. 

"We are delighted to welcome Dr. Stein to the Theseus Board as we advance development of our THE-630 and THE-349 programs, while also expanding our early-stage pipeline," said Tim Clackson, Ph.D., President and Chief Executive Officer of Theseus. "Dr. Stein's depth and breadth of oncology expertise, and extensive track record of bringing effective medicines through development and to patients, will be invaluable as we continue to build Theseus as a leading precision oncology company."

Dr. Stein currently serves as Executive Vice President, Chief Medical Officer of the global biopharmaceutical company, Incyte, where he develops strategy for Incyte's therapeutic candidates and oversees verticals including clinical development, regulatory affairs and medical affairs. Previously, he worked at Novartis Pharmaceuticals Corporation, where he most recently served as Senior Vice President, U.S. Clinical Development & Medical Affairs at Novartis Oncology. Dr. Stein previously worked at GSK (formerly GlaxoSmithKline) as Vice President, Global Oncology, Clinical Development and as Head of Medicines Development for Hematology and Supportive Care. Dr. Stein was previously an assistant professor in the Department of Medicine at the University of Pennsylvania, where he had also completed a fellowship in hematology and oncology. Dr. Stein has served as a member of Kura Oncology's Board of Directors since January 2017. He earned his medical degree from the University of Witwatersrand in Johannesburg, South Africa.

Dr. Stein added, "Theseus is backed by a foundation of success in targeted oncology, and I look forward to contributing to their continued growth and development through the Company's near-term clinical milestones, and onward through the complex clinical and regulatory pathways that influence development in the targeted oncology space." 

About Theseus Pharmaceuticals, Inc.
Theseus is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients through the discovery, development and commercialization of transformative targeted therapies. Theseus is working to outsmart cancer resistance by developing pan-variant tyrosine kinase inhibitors (TKIs) to target all known classes of cancer-causing and resistance mutations that lead to variants in a particular protein in a given type of cancer. Theseus' lead product candidate, THE-630, is a pan-variant KIT inhibitor for the treatment of patients with advanced gastrointestinal stromal tumors (GIST), whose cancer has developed resistance to earlier lines of kinase inhibitor therapy. Theseus is also developing THE-349, a fourth-generation, selective epidermal growth factor receptor (EGFR) inhibitor for C797X-mediated resistance to first- or later-line osimertinib treatment in patients with non-small cell lung cancer (NSCLC). For more information, visit www.theseusrx.com.

Cautionary Statement Regarding Forward Looking Statements
Certain statements included in this press release are not historical facts but are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as "will," "anticipate," "expect," "continue," "forward," and similar expressions that predict or indicate future events or trends or that are not statements of historical matters, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include, but are not limited to, statements regarding: Theseus' strategy, future operations, prospects and plans; the structure and timing of its preclinical studies and clinical trials, expected milestones, market opportunity and sizing and objectives of management; and the expected contributions of Dr. Stein to our business in the future.

Actual results may differ materially from those indicated by such forward-looking statements as a result of various important risks, uncertainties and other factors, including, but not limited to: uncertainties inherent in preclinical studies; uncertainties regarding whether results from preclinical studies will be predictive of the results of future trials; risks related to the expected timing of submissions to regulatory authorities, and other risks, uncertainties and other factors such as those described from time to time in the reports Theseus files with the Securities and Exchange Commission (SEC), including Theseus' Form 10-K for the year ended December 31, 2021, and Quarterly Reports on Form 10-Q for the quarters ended March 31, 2022 and June 30, 2022, which are on file with the SEC and available on the SEC's website at https://www.sec.gov/. However, new risk factors and uncertainties may emerge from time to time which may cause actual results to differ materially from those anticipated or implied by the forward looking statements in this press release, and it is not possible to predict all risk factors and uncertainties. Accordingly, readers are cautioned not to place undue reliance on these forward-looking statements. Any forward-looking statements contained in this press release are based on the current expectations of Theseus' management team and speak only as of the date hereof, and Theseus specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law.

Media Contact
Amy Jobe, Ph.D.
LifeSci Communications
315-879-8192
ajobe@lifescicomms.com 

Investor Contacts
Christen Baglaneas
Theseus Pharmaceuticals
857-706-4993
christen.baglaneas@theseusrx.com 

Josh Rappaport
Stern Investor Relations
212-362-1200
josh.rappaport@sternir.com

View original content:https://www.prnewswire.com/news-releases/theseus-pharmaceuticals-appoints-steven-stein-md-to-board-of-directors-301652881.html

SOURCE Theseus Pharmaceuticals

FAQ

What is the significance of Dr. Steven Stein's appointment to Theseus Pharmaceuticals?

Dr. Steven Stein's appointment is significant as it brings extensive oncology experience to Theseus Pharmaceuticals, which may enhance the strategic direction of their clinical programs.

What are THE-630 and THE-349 programs at Theseus Pharmaceuticals?

THE-630 is a treatment for advanced gastrointestinal stromal tumors, while THE-349 targets non-small cell lung cancer, aiming to address resistance to existing therapies.

When was Dr. Steven Stein appointed to the Board of Directors of Theseus Pharmaceuticals?

Dr. Steven Stein was appointed to the Board of Directors on October 19, 2022.

What is Dr. Steven Stein's background before joining Theseus Pharmaceuticals?

Before joining Theseus, Dr. Stein served as Chief Medical Officer at Incyte and held significant roles at Novartis and GSK in oncology clinical development.