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TC BioPharm (Holdings) PLC (NASDAQ: TCBP) is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative immunotherapy products. The company leverages its proprietary allogeneic gamma-delta T (GD-T) cell platform to create novel therapies aimed at treating cancer and viral infections.
Gamma-delta T cells are unique immune cells that possess characteristics of both the innate and adaptive immune systems, enabling them to distinguish between healthy and diseased tissues. TC BioPharm's approach uses these cells to develop effective treatments for various cancers, including both liquid and solid tumors.
Notable achievements include the initiation of phase 2b/3 pivotal trials for OmnImmune® in the treatment of acute myeloid leukemia (AML) using their proprietary allogeneic CryoTC technology, which allows for the distribution of frozen cell products to clinics worldwide. The company also maintains a robust pipeline targeting solid tumors and has built a significant intellectual property portfolio.
Recent developments highlight TC BioPharm's dynamic progress:
- March 1, 2024: CEO Bryan Kobel featured on 'The Big Biz Show,' discussing the company's ongoing advancements.
- March 18, 2024: An institutional investor exercised warrants resulting in a net cash infusion of $1.17M, strengthening the company’s financial position.
- March 19, 2024: The company adjourned its General Meeting to gather additional information for a shareholder vote.
- April 2, 2024: Announcement of a new streamlined manufacturing process to increase patient treatment capacity and reduce costs by 85%.
- April 4, 2024: Execution of a non-binding letter of intent to acquire assets focused on CAR-NK cell therapies, enhancing their cancer treatment capabilities.
- May 6, 2024: Agreement for the immediate exercise of certain warrants, raising approximately £3.1M for clinical trials and operations.
- May 6, 2024: Announcement of a second letter of intent to acquire a company developing CAR-T therapies for solid tumors and autoimmune diseases.
- May 15, 2024: Launch of a compassionate use program in the UK for TCB-008, providing new treatment options for patients ineligible for clinical trials.
TC BioPharm continues to focus on expanding its therapeutic platform, leveraging strategic partnerships, and advancing its clinical trials, all while upholding its commitment to improving patient outcomes.
TC BioPharm (NASDAQ: TCBP) has outlined its 2023 strategic plan, focusing on the development of its lead product, TCB-008, an allogeneic gamma-delta T cell therapy for cancer. The Company aims to pursue exclusive partnerships for clinical research, enhancing its competitive edge in the evolving cell therapy landscape. TCB-008 is set for FDA IND filing in Q3 2023 for Acute Myeloid Leukemia and will expand into CAR therapy targeting ovarian cancer. With over 313,000 new ovarian cancer cases reported in 2020, the Company is aligning its assets for better market positioning. TCBP is focused on establishing collaborations and increasing its intellectual property portfolio, aiming for a pivotal role in gamma-delta T cell therapies. The CEO emphasized the importance of partnerships and efficient capital management for long-term growth.
TC BioPharm (NASDAQ: TCBP), a clinical-stage biotechnology company, is set to participate in the Sequire Investor Summit from April 24-26, 2023, in San Juan, Puerto Rico. This summit offers unique tax advantages for attendees, aimed at enhancing their investment strategies. Keynote panels and training sessions will be led by industry experts, covering the latest trends and best practices.
On April 26, at 11:00 am ET, TC BioPharm management will present on Track 2. The company's focus is on developing gamma-delta T cell therapies for cancer treatment, with ongoing clinical trials targeting acute myeloid leukemia. TC BioPharm is recognized for its allogeneic approach and maintains a robust patent portfolio in this innovative field.
The report titled "Global CD276 Antibody Clinical Trials & Market Sales Forecast 2028" highlights the emerging potential of CD276 immune checkpoint inhibitors in cancer treatment. It forecasts a market value exceeding
TC BioPharm (NASDAQ: TCBP) announced the closure of a public offering, issuing 3,437,500 American Depositary Shares (ADSs), priced at $1.60 each, raising approximately $5.5 million. This includes Series C warrants exercisable at $1.75 per ADS. The funding is intended to extend the company's cash runway through the US FDA IND filing. H.C. Wainwright & Co. acted as the exclusive placement agent for this offering, filed with the SEC on March 27, 2023. TC BioPharm specializes in gamma-delta T cell therapies for cancer, leading pivotal clinical studies in oncology.
TC BioPharm (NASDAQ: TCBP) announced the pricing of a public offering of 3,437,500 American Depositary Shares (ADSs) at $1.60 each, aiming to raise $5.5 million before expenses. The offering, expected to close on or about March 30, 2023, includes Series C warrants with an exercise price of $1.75 per ADS. Proceeds will support working capital and corporate purposes. Additionally, existing warrants for 2,800,000 ADSs issued in November 2022 will be amended to reduce exercise price to $1.75 upon closing. The registration statement was effective as of March 27, 2023.
TC BioPharm (NASDAQ: TCBP) has announced a corporate restructuring aimed at reducing overhead and extending its cash runway. The company plans to cut its workforce by up to 30%, with an expected annual cost saving of over $3 million. This restructuring aligns with TC BioPharm's strategic focus on advancing its lead therapeutic program, TCB-008, and other clinical trials. The CEO emphasized the necessity of these changes to ensure the company's long-term sustainability amid challenging market conditions. The company is also exploring non-dilutive funding options and strategic partnerships to bolster its operations.
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