Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of - TAK STOCK NEWS

Takeda (TSE: 4502/NYSE:TAK) announced its participation in the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO) from May 31-June 4, 2024, in Chicago. The company will present data on its oncology pipeline and product portfolio, covering various cancers such as colorectal, lung, lymphoma, multiple myeloma, and leukemia. Presentations will include both clinical and real-world data aimed at enhancing treatment approaches. Key highlights will feature data on Hodgkin lymphoma and colorectal cancer, emphasizing Takeda’s commitment to combining internal innovations with external partnerships. Takeda continues its mission to provide transformative medicines and improve patient care.

Takeda announced its FY2023 full year results, showing +5.9% revenue growth at AER and +1.5% at CER, with a -13.3% core operating profit change at CER due to generic impact and R&D investment. The company aims for a 100-250 basis points core operating profit margin improvement each year from FY2025. Takeda's financial performance exceeded expectations, with three new therapy approvals from the U.S. FDA in FY2023 and up to six NMEs in phase 3 development in FY2024. The company plans to implement an efficiency program in FY2024 to drive organizational agility, procurement savings, and leverage data, digital, and technology capabilities.

Takeda (NYSE:TAK) has received a positive recommendation from the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) for the approval of fruquintinib, a targeted therapy for previously treated metastatic colorectal cancer (mCRC). If approved by the European Commission, fruquintinib will be a novel treatment in the EU, highlighting its status as the first therapy to inhibit all three vascular endothelial growth factor receptors (VEGFR-1, -2, -3) for mCRC in over a decade. The therapy showed significant improvements in overall survival and progression-free survival in Phase 3 FRESCO-2 trials compared to the current standard care.

Fruquintinib's potential impacts are substantial, offering a new chemotherapy-free option that improves patient outcomes. It has already been approved in the U.S. under the brand name FRUZAQLA® as of November 2023, and launched in China in 2018 as ELUNATE®. Key safety information includes risks such as hypertension, hemorrhagic events, infections, and hepatotoxicity among others.

Neurocrine Biosciences announces positive Phase 2 data for NBI-1065845 in adults with Major Depressive Disorder. The SAVITRI™ study met primary and key secondary endpoints, showing statistically significant reductions in MADRS total score at both Day 28 and Day 56. NBI-1065845 was well-tolerated with low discontinuation rates. The data suggests potential as a first-in-class treatment for MDD.

Takeda, Astellas, and Sumitomo Mitsui Banking have announced a master agreement to establish a joint venture company dedicated to the incubation of early drug discovery programs in Japan. The new company aims to advance innovative drug discovery programs, foster entrepreneurship, and create start-up companies to unleash the potential of the drug discovery ecosystem in Japan.

Takeda's ENTYVIO (vedolizumab) receives FDA approval for subcutaneous administration in maintenance therapy for moderately to severely active Crohn’s disease. The drug is now available in the U.S. for both IV and SC administrations for the treatment of adults with Crohn’s disease and ulcerative colitis.

Takeda announces $14.6 million investment in CSR program, welcoming eight new grant partners. Total contributions reach $54.1 million since 2021. Focus on Food is Health and Building STEM Foundations to promote equity in under-resourced communities.

Takeda's 'In Their Shoes' initiative sheds light on the daily struggles of IBD patients in the UAE, aiming to raise awareness and empathy through a 24-hour simulation. IBD, a chronic inflammatory condition affecting the gastrointestinal tract, has seen a rise in incidence globally, including in newly industrialized countries like the UAE.

Takeda (TAK) announces Board of Directors changes, proposing new candidates and appointing a new CFO. Mr. Milano Furuta to succeed Mr. Constantine Saroukos as CFO. Several directors to join the Board with defined roles and tenures.