Shattuck Labs to Present Two Posters at the 2022 American Association for Cancer Research (AACR) Annual Meeting

Rhea-AI Summary

Shattuck Labs, Inc. (NASDAQ: STTK) announced the acceptance of two posters for presentation at the American Association for Cancer Research (AACR) Annual Meeting, April 8-13, 2022, in New Orleans. The posters will feature preclinical data from their GADLEN™ and ARC® platforms, focusing on cancer treatment advancements. Dr. Anne Lai will present on bispecific gamma delta T cell engagers on April 12, while Dr. George Fromm and Kyung Jin Yoo will discuss LIGHT costimulation with TIGIT blockade on April 13. More details and poster access will be available on their website post-event.

AUSTIN, Texas and DURHAM, N.C., March 09, 2022 (GLOBE NEWSWIRE) -- Shattuck Labs, Inc. (Shattuck) (NASDAQ: STTK), a clinical-stage biotechnology company pioneering the development of bi-functional fusion proteins as a new class of biologic medicine for the treatment of patients with cancer and autoimmune disease, today announced that two posters have been accepted for presentation at the American Association for Cancer Research (AACR) Annual Meeting, which is being held April 8-13, 2022 at the Ernest N. Morial Convention Center in New Orleans, Louisiana. The first poster will highlight preclinical data from the company’s GADLEN™ platform, while the second will highlight preclinical data from SL-9258 (TIGIT-Fc-LIGHT), derived from the company’s ARC^® platform, demonstrating its ability to broaden the activity of checkpoint inhibitors through targeted myeloid cell and effector lymphocyte activation.

Presentation Details

Title: Bispecific gamma delta T cell engagers containing butyrophilin 2A1/3A1 heterodimeric fusion protein efficiently activate Vg9Vd2 T cells and promote tumor cell killing
Presenter: Dr. Anne Lai, Ph.D., Principal Scientist, Shattuck
Session: Immunology - Immunomodulatory Agents and Interventions 2
Date/Time: Tuesday, April 12, 2022, 1:30 p.m. to 5:00 p.m. ET
Location: New Orleans Convention Center, Exhibit Halls D-H, Poster Section 37
Abstract Number: 3514

Title: LIGHT (TNFSF14) costimulation with TIGIT blockade broadens the activity of checkpoint inhibitors (CPIs) into CPI refractory and resistant tumors through targeted myeloid cell and effector lymphocyte activation
Presenters: Dr. George Fromm, Ph.D., Vice President of Research and Development, Shattuck, and Kyung Jin Yoo, Research Associate, Shattuck
Session: Immunology - Combination Immunotherapies 2
Date/Time: Wednesday, April 13, 2022, 9:00 a.m. to 12:30 p.m. ET
Location: New Orleans Convention Center, Exhibit Halls D-H, Poster Section 37
Abstract Number: 4214

Additional meeting information can be found on the AACR website, https://www.aacr.org. The posters will be available under the Events & Presentations section of the Company’s website shortly after the event.

About Shattuck Labs, Inc.
Shattuck Labs, Inc. (NASDAQ: STTK) is a clinical-stage biotechnology company pioneering the development of bi-functional fusion proteins as a new class of biologic medicine for the treatment of patients with cancer and autoimmune disease. Compounds derived from Shattuck’s proprietary Agonist Redirected Checkpoint, ARC®, platform simultaneously inhibit checkpoint molecules and activate costimulatory molecules within a single therapeutic. The company’s SL-172154 (SIRPα-Fc-CD40L) program, which is designed to block the CD47 immune checkpoint and simultaneously agonize the CD40 pathway, is being evaluated in two Phase 1 trials. A second product candidate, SL-279252 (PD1-Fc-OX40L), is being evaluated in a Phase 1 trial in solid tumors or lymphomas. Additionally, the company is advancing a proprietary Gamma Delta T Cell Engager, GADLEN™, platform, which is designed to bridge gamma delta T cells to tumor antigens for the treatment of patients with cancer. Shattuck has offices in both Austin, Texas and Durham, North Carolina. For more information, please visit: www.ShattuckLabs.com.

Investor Contact:
Conor Richardson
Senior Director, Finance & Investor Relations
Shattuck Labs, Inc.
InvestorRelations@shattucklabs.com 

Media Contact:
Stephanie Ascher
Managing Director
Stern Investor Relations, Inc.
Stephanie.ascher@sternir.com 

 

FAQ

What are the key presentations by Shattuck Labs at the AACR Annual Meeting 2022?

Shattuck Labs will present two posters: one on bispecific gamma delta T cell engagers by Dr. Anne Lai on April 12, and another on LIGHT costimulation with TIGIT blockade by Dr. George Fromm and Kyung Jin Yoo on April 13.

When is the AACR Annual Meeting where Shattuck Labs will present?

The AACR Annual Meeting will be held from April 8 to April 13, 2022.

What is the focus of Shattuck Labs' research presented at AACR 2022?

The research focuses on advancements in cancer treatment using preclinical data from their GADLEN™ and ARC® platforms.

Where can I find the posters presented by Shattuck Labs after the AACR event?

The posters will be available under the Events & Presentations section of Shattuck Labs' website shortly after the event.

What is the significance of the GADLEN™ and ARC® platforms for Shattuck Labs?

The GADLEN™ platform aims to bridge gamma delta T cells to tumor antigens, while the ARC® platform simultaneously inhibits checkpoint molecules and activates costimulatory molecules, both contributing to innovative cancer therapies.