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Shattuck Labs, Inc. - STTK STOCK NEWS

Welcome to our dedicated page for Shattuck Labs news (Ticker: STTK), a resource for investors and traders seeking the latest updates and insights on Shattuck Labs stock.

Shattuck Labs, Inc. (NASDAQ: STTK) is a clinical-stage biotechnology company at the forefront of developing innovative bi-functional fusion proteins. These unique proteins represent a new class of biologic medicine aimed at treating patients with cancer and autoimmune diseases. Shattuck's proprietary Agonist Redirected Checkpoint (ARC®) platform is designed to inhibit checkpoint molecules and activate costimulatory molecules with a single therapeutic, a groundbreaking approach in the biotechnology field.

The company's lead product candidate, SL-172154 (SIRPα-Fc-CD40L), is engineered to block the CD47 immune checkpoint and activate the CD40 pathway simultaneously. Currently, SL-172154 is in multiple Phase 1 clinical trials targeting various cancers, including platinum-resistant ovarian cancer and acute myeloid leukemia (AML). Another promising candidate, SL-279252 (PD1-Fc-OX40L), is being developed in collaboration with Takeda Pharmaceuticals and is also in Phase 1 trials.

Shattuck Labs recently embarked on an exciting collaboration with Ono Pharmaceutical to develop bifunctional fusion proteins for autoimmune and inflammatory diseases. This partnership includes a significant financial package with potential milestone payments and royalties, reinforcing Shattuck's strong financial condition and innovative capabilities. Additionally, the company's proprietary gamma delta T cell engager platform, GADLEN™, promises to bridge gamma delta T cells to tumor antigens, offering new hope for cancer treatment.

Recent achievements include rapid enrollment in clinical trials and the FDA's orphan drug designation for SL-172154, highlighting the urgent need for new AML treatments. Shattuck is also actively participating in several high-profile conferences, sharing their latest research and clinical progress. The company is headquartered in Austin, Texas, and Durham, North Carolina, and continues to leverage its scientific expertise to address unmet medical needs.

  • Core Business: Development of bi-functional fusion proteins for cancer and autoimmune diseases.
  • Recent Achievements: FDA orphan drug designation for SL-172154, collaboration with Ono Pharmaceutical.
  • Current Projects: Phase 1 trials for SL-172154 and SL-279252, development of GADLEN™ platform.
  • Financial Condition: Strong financial backing with potential milestone payments from partnerships.
  • Partnerships: Collaborations with Ono Pharmaceutical and Takeda Pharmaceuticals.
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Shattuck Labs, Inc. reveals preclinical data at AACR Annual Meeting 2024 showing TRIM7 inhibition can combat immune checkpoint therapy resistance. TRIM7 inhibitors may reverse acquired resistance to PD-1/L1 blockade, potentially benefiting cancer patients.
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Shattuck Labs, Inc. (STTK) to participate in the 23rd Annual Needham Virtual Healthcare Conference. Dr. Taylor Schreiber, the CEO, will present on April 8, 2024, discussing the development of bi-functional fusion proteins for cancer and autoimmune disease treatment.
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Shattuck Labs, Inc. (STTK) appoints Dr. Clay Siegall and Dr. Kate Sasser to its Board of Directors. Both bring valuable industry experience to lead late-stage clinical development of SL-172154, a promising new therapy for cancer and autoimmune diseases.
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Shattuck Labs, Inc. announced positive topline data from ongoing clinical trials of SL-172154 in combination with azacitidine in frontline HR-MDS and TP53m AML patients. The company completed enrollment in Phase 1B dose-expansion cohorts and entered into a collaboration with Ono Pharmaceutical Co. The financial results for Q4 2023 showed $130.6 million in cash and cash equivalents, with reduced R&D and G&A expenses.
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Shattuck Labs, Inc. (STTK) announced participation in investor conferences to discuss the development of bi-functional fusion proteins for cancer and autoimmune disease treatment. Key conferences include TD Cowen 44th Annual Health Care Conference, Leerink Partners Global Biopharma Conference 2024, and Citi's Biotech C-Suite Fireside Chat Series.
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Ono Pharmaceutical Co., Ltd. announced a drug discovery collaboration and option agreement with Shattuck Labs, Inc. to develop bifunctional fusion proteins for autoimmune and inflammatory diseases. Shattuck will generate fusion proteins for targets using its technology, with Ono having the option to develop and commercialize resulting drug candidates worldwide. The agreement includes research funding, an upfront payment, milestones, and royalties up to $227 million. Pre-clinical studies showed promising immunoregulatory effects of the fusion proteins.
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Shattuck Labs, Inc. (STTK) collaborates with Ono Pharmaceutical Co., Ltd. to develop novel bifunctional fusion proteins for autoimmune and inflammatory diseases. The agreement includes significant financial incentives up to $227 million, showcasing the potential of this partnership in advancing biologic medicine.
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Shattuck Labs, Inc. (STTK) provided a corporate update, highlighting key milestones anticipated in 2024. The company delivered key safety and efficacy data in 2023 and strengthened financial resources. Preliminary results demonstrate initial anti-tumor activity and an acceptable safety profile for SL-172154, with opportunities in HR-MDS, AML, and ovarian cancer. Shattuck also announced a $50 million registered offering of common stock and concurrent private placement of pre-funded warrants. The company expects its cash and investments to be sufficient to fund operations into 2026.
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Shattuck Labs, Inc. (STTK) to present corporate update at 42nd Annual J.P. Morgan Healthcare Conference
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Shattuck Labs, Inc. (NASDAQ: STTK) announced the pricing of a registered offering of 4,651,163 shares of common stock at $6.45 per share, as well as a private placement of pre-funded warrants to purchase 3,100,823 shares of common stock at a purchase price of $6.4499 per pre-funded warrant, with expected gross proceeds of approximately $50 million.
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FAQ

What is the current stock price of Shattuck Labs (STTK)?

The current stock price of Shattuck Labs (STTK) is $1.235 as of November 15, 2024.

What is the market cap of Shattuck Labs (STTK)?

The market cap of Shattuck Labs (STTK) is approximately 60.6M.

What is Shattuck Labs, Inc.'s core business?

Shattuck Labs focuses on developing bi-functional fusion proteins for cancer and autoimmune diseases.

What are the main product candidates of Shattuck Labs?

The main candidates are SL-172154 and SL-279252, both currently in Phase 1 clinical trials.

What is the ARC® platform?

The ARC® platform is Shattuck's proprietary technology designed to inhibit checkpoint molecules and activate costimulatory molecules within a single therapeutic.

Who are Shattuck Labs' key partners?

Shattuck Labs has collaborations with Ono Pharmaceutical and Takeda Pharmaceuticals.

Where is Shattuck Labs headquartered?

Shattuck Labs is headquartered in Austin, Texas, and Durham, North Carolina.

What is SL-172154?

SL-172154 is an investigational ARC® fusion protein designed to block the CD47 immune checkpoint and activate the CD40 pathway for cancer treatment.

What recent achievements has Shattuck Labs made?

Recent achievements include the FDA orphan drug designation for SL-172154 and a collaboration with Ono Pharmaceutical.

What is the GADLEN™ platform?

The GADLEN™ platform is designed to bridge gamma delta T cells to tumor antigens, offering new treatment options for cancer.

What financial condition is Shattuck Labs in?

Shattuck Labs has a strong financial condition with potential milestone payments from partnerships.

What are some upcoming events for Shattuck Labs?

Shattuck Labs will participate in several high-profile conferences to share their latest research and clinical progress.

Shattuck Labs, Inc.

Nasdaq:STTK

STTK Rankings

STTK Stock Data

60.61M
47.73M
13.41%
74.21%
4.56%
Biotechnology
Pharmaceutical Preparations
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United States of America
AUSTIN