Stoke Therapeutics, Inc. - STOK STOCK NEWS

Stoke Therapeutics, Inc. (Nasdaq: STOK), a pioneering biotechnology company, announced that CEO Edward M. Kaye, M.D., will participate in a fireside chat at the Needham Virtual Epilepsy & Pain – Specialty Therapeutics Conference on December 10, 2020, at 12:45 p.m. ET. The live audio webcast will be accessible on Stoke’s Investors & Media section of their website, with a replay available for 30 days. Stoke focuses on treating genetic diseases by upregulating protein expression, targeting autosomal dominant haploinsufficiencies to potentially restore health.

Stoke Therapeutics (Nasdaq: STOK) presented data at the 2020 American Epilepsy Society Annual Meeting regarding STK-001, a potential treatment for Dravet syndrome. Key findings include a baseline analysis from the BUTTERFLY study indicating significant cognitive impairments in children with Dravet, even when treated with existing therapies. The MONARCH study is underway to assess the safety and efficacy of STK-001. Preclinical data show promise in addressing the genetic cause of Dravet syndrome by potentially modifying disease progression and improving patient quality of life.

Stoke Therapeutics (Nasdaq: STOK) announced four abstracts on Dravet syndrome for the upcoming American Epilepsy Society 2020 Virtual Annual Meeting. Highlights include baseline data from the BUTTERFLY study evaluating neurodevelopmental status in children, details on the ongoing Phase 1/2a MONARCH study of STK-001, and new preclinical data supporting the efficacy of a TANGO antisense oligonucleotide. STK-001 aims to be a disease-modifying therapy addressing the genetic cause of Dravet syndrome, which affects around 35,000 individuals in select regions.

Stoke Therapeutics (Nasdaq: STOK) has successfully closed its public offering of 2,875,000 shares at $39.00 each, raising approximately $105.1 million in net proceeds. The offering included 375,000 shares from underwriters' option. Funds will support research, clinical development, and manufacturing for their product candidates, including STK-001 for Autosomal Dominant Optic Atrophy and other general corporate purposes. This offering was conducted under a previously filed SEC registration statement.

Stoke Therapeutics (Nasdaq: STOK) has priced an underwritten public offering of 2,500,000 shares at $39.00 each, expecting to raise $97.5 million. The offering will close around November 24, 2020, subject to customary conditions. Stoke has provided underwriters a 30-day option to purchase an additional 375,000 shares. Proceeds will support research, clinical development of STK-001 for Autosomal Dominant Optic Atrophy, and general corporate needs. This offering follows a registration statement with the SEC.

Stoke Therapeutics (Nasdaq: STOK) has announced a proposed underwritten public offering of up to 2,500,000 shares of common stock, with a 30-day option for underwriters to purchase an additional 375,000 shares. Proceeds from the offering will fund research and clinical development for its product candidates, including the late-stage STK-001 and new treatments for Autosomal Dominant Optic Atrophy. The offering is subject to market conditions and there are no guarantees regarding completion or terms.

Stoke Therapeutics (Nasdaq: STOK) reported Q3 2020 results, showing a net loss of $13.7 million ($0.41/share) compared to $8.6 million ($0.26/share) in Q3 2019. R&D expenses increased to $8.1 million from $6.5 million, while G&A expenses rose to $5.6 million from $3.3 million. The company continues to advance its MONARCH study for STK-001 in Dravet syndrome, with preliminary data expected in 2021. Stoke also announced the nomination of OPA1 as a preclinical target with potential to treat autosomal dominant optic atrophy, a condition currently lacking effective treatments.

Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology company focused on treating genetic diseases, announced that CEO Edward M. Kaye will present at the Stifel 2020 Virtual Healthcare Conference on November 16, 2020, at 3:20 p.m. ET. A live webcast will be available on the company's website, with a replay accessible for 30 days after the event. Stoke aims to develop solutions for genetic diseases through precise protein expression upregulation, targeting conditions caused by mutated genes. For more details, visit Stoke Therapeutics.

Stoke Therapeutics, Inc. (Nasdaq: STOK), a clinical-stage biotechnology firm, announced that CEO Edward M. Kaye, M.D., will participate in a fireside chat during the 29th Annual Credit Suisse Virtual Healthcare Conference on November 9, 2020, at 10:15 a.m. ET. This session aims to highlight the company's innovative approach to treating genetic diseases by precisely upregulating protein expression. Investors can access a live audio webcast of the chat on Stoke’s website, which will also feature a replay for 30 days.