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Introduction to SOPHiA GENETICS SA

SOPHiA GENETICS SA is a pioneering healthcare technology company dedicated to establishing data-driven medicine as the global standard for clinical diagnostics and life sciences research. Harnessing the power of genomics, bioinformatics, and machine learning, the company has built a robust cloud-native SaaS platform that transforms complex, multimodal data into real-time, actionable insights. With a heritage rooted in Swiss precision and high medical standards, SOPHiA GENETICS combines advanced AI-based analytics with stringent quality assurance protocols to support clinical laboratories and research institutions worldwide.

Core Technology: The SOPHiA DDM™ Platform

The cornerstone of SOPHiA GENETICS’ offerings is the SOPHiA DDM™ Platform, an innovative solution designed to analyze genomic and other diagnostic data derived from next-generation sequencing (NGS) and additional diagnostic modalities. This comprehensive platform not only supports clinical decision-making through sophisticated analytical algorithms but also facilitates the secure storage and curation of patient DNA sequence data. By integrating complex data streams with artificial intelligence, the platform empowers hospitals, laboratories, and biopharma institutions to achieve faster diagnoses, significantly reduce costs, and streamline workflows.

Advanced Analytics and Data-Driven Medicine

At its core, SOPHiA GENETICS utilizes advanced machine learning algorithms and bioinformatics tools to decode complex genomic signatures. The platform analyzes diverse data sets—ranging from traditional sequencing outputs to imaging and clinical data—to provide detailed, actionable insights. These insights enable clinicians to make data-driven decisions in personalized oncology and rare disorder management, further underlining the company’s commitment to precision medicine. The early integration of AI in clinical settings underlines the company’s focus on operational excellence and innovation, enabling consistent results and reproducibility in genomic testing.

Global Network and Collaborative Research

Operating from its headquarters in Switzerland, SOPHiA GENETICS extends its reach through an extensive global network of hospitals, academic centers, and laboratories. This international collaboration not only mitigates the challenges associated with complex genomics but also fosters knowledge sharing among more than 100 healthcare institutions. In doing so, the company creates a robust community that drives continuous improvements in diagnostic accuracy and operational efficiency. By facilitating real-time data exchange and collaborative research, SOPHiA GENETICS is at the forefront of demystifying the complexities of modern genomics.

Clinical Applications and Impact

SOPHiA GENETICS is uniquely positioned within the competitive landscape as a transformative player in precision oncology diagnostics. Its innovative platform is deployed in various clinical settings—from routine diagnostics in hospitals to advanced research in oncology and rare genetic disorders. The application of the SOPHiA DDM™ Platform extends to the detection of critical genomic variants and the monitoring of treatment responses, including low frequency variant tracking in longitudinal studies. By ensuring nearly 100% reproducibility in testing outcomes, the company enables clinicians to offer more accurate, faster, and cost-effective patient care, thereby addressing some of the most pressing challenges in modern medicine.

Operational Excellence and Quality Assurance

Leveraging Swiss precision, SOPHiA GENETICS maintains exceptionally high standards in quality assurance and patient data security. The company adopts best practices in clinical bioinformatics which facilitate reliable and efficient diagnostic processes. Through continuous refinement of its analytical algorithms and strict adherence to medical regulatory guidelines, SOPHiA GENETICS ensures that the clinical genomic data processed via its platform is both comprehensive and consistent, bolstering confidence among its institutional partners.

Integration of Cutting-Edge Technologies

The company's commitment to innovation is evident in its continuous development of new tools and applications built on the core SOPHiA DDM™ Platform. Its solutions extend to advanced liquid biopsy tests and solid tumor profiling applications, demonstrating the versatility and adaptability of its technology. The platform's ability to seamlessly integrate various data types makes it a critical asset for institutions seeking to adopt a more efficient, data-driven approach in precision oncology research and diagnostics.

Differentiation in a Competitive Landscape

Unlike traditional diagnostic methods which often struggle with high operational costs and lengthy turnaround times, the SOPHiA DDM™ Platform offers a decentralized, AI-driven solution that significantly improves workflow efficiency. The global clinical genomics community nurtured by SOPHiA GENETICS serves as a distinct competitive advantage, offering a continuous feedback loop and facilitating rapid innovation in clinical testing methodologies. The focus on cost reduction, operational speed, and data security positions the company as a trusted partner for healthcare providers and research institutions around the world.

Security, Compliance, and Ethical Standards

SOPHiA GENETICS is deeply committed to safeguarding patient data. The platform is engineered to meet high standards of genomic privacy and data security, ensuring that sensitive patient information is securely stored and strictly controlled. This commitment not only builds trust among healthcare professionals and regulatory bodies but also underscores the company’s dedication to ethical standards in the rapidly evolving field of data-driven medicine.

Conclusion

In summary, SOPHiA GENETICS SA stands at the intersection of advanced genomics and innovative data analytics. Its cloud-native platform, underpinned by AI and rigorous quality processes, provides a comprehensive solution for clinical diagnostics and research in precision oncology and beyond. With a strong focus on operational efficiency, data security, and collaborative research, the company continues to transform how medical insights are generated, offering a powerful tool that streamlines complex genomic analyses and fosters better patient outcomes worldwide.

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SOPHiA GENETICS (SOPH) executives to participate in fireside chat at 44th Annual TD Cowen Health Care Conference. The chat will be webcast live on the company's Investor Relations website, with a replay available post-event.
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SOPHiA GENETICS (SOPH) will release its financial results for Q4 and full-year 2023 on March 5, 2024. The company, known for data-driven medicine, will host a conference call to discuss the results and business outlook.
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SOPHiA GENETICS and AstraZeneca Spain have expanded their HRD testing program in Spain to support the molecular diagnosis of ovarian cancer. The program aims to increase access to local testing for homologous recombination deficiency (HRD) throughout the country, with the goal of making vital testing available to thousands more patients. AstraZeneca Spain has named SOPHiA GENETICS its preferred partner in deploying HRD testing throughout Spain, offering the option for HRD testing to become available to more laboratories. The collaboration aims to increase accelerated diagnostics for patients and support clinicians in precision treatment planning.
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SOPHiA GENETICS (SOPH) announced a collaboration with Bioma4me, a Brazil-based company focused on genetic sequencing to drive precision medicine in Brazil. Bioma4me will use SOPHiA DDM™ Platform to advance and streamline its genetic testing capabilities, enabling fast turnaround time for results and full ownership over its data. Through this partnership, Bioma4me aims to advance the field of oncology, microbiome, and genetic diseases in Latin America.
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RareCyte Inc. has partnered with SOPHiA GENETICS to implement the SOPHiA DDM™ Platform for its Precision Biology Services portfolio. This partnership will enable RareCyte to provide DNA sequencing of circulating tumor cells and cell-free DNA for cancer patient testing, supporting the advancement of oncology, immuno-oncology, maternal-fetal health, and cell and gene therapy.
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SOPHiA GENETICS partners with Karkinos Healthcare to advance cancer research and personalized cancer care in India. The partnership aims to expand access to precision oncology and equip local health institutions with the tools and technology needed to practice data-driven medicine. Karkinos Healthcare will use the SOPHiA DDM™ Platform to advance research and streamline workflow for a variety of blood cancers and solid tumors, with a focus on precision medicine for the underprivileged population of India.
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SOPHiA GENETICS (Nasdaq: SOPH) reports continued revenue growth driven by strong adoption and analysis volume of the SOPHiA DDM™ Platform. The company will present its near-term growth strategy at the 42nd annual J.P. Morgan Healthcare Conference, highlighting a record 315,000+ analyses globally in 2023, with over 1.5 million genomic profiles analyzed worldwide. New customer count for 2023 includes 87 core genomics customers globally, resulting in a current network of 750+ customers using SOPHiA DDM™ globally. The company also announced new U.S.-based customer Tennessee Oncology exploring MSK-ACCESS® powered with SOPHiA DDM™, Latin American healthcare network Dasa expanding to incorporate the liquid biopsy application, and The Royal Marsden live on the SOPHiA DDM™ Platform to support HRD testing and research.
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SOPHiA GENETICS (Nasdaq: SOPH) collaborates with Exactis Innovation, a non-profit network of hospital partners across Canada, to fuel cancer research and data-driven decision-making through the SOPHiA DDM™ platform. The collaboration aims to improve cancer survivorship in Canada by leveraging real-world data insights from multimodal datasets. The partnership will also enable Exactis to implement leading cancer testing solutions for its patient population.
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SOPHiA GENETICS (Nasdaq: SOPH) partners with Hôpital Saint-Louis in Paris to implement the SOPHiA DDM™ Platform for research on Myeloid Disorders, aiming to provide data-driven care to patients with MPNs.
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SOPHiA GENETICS (NASDAQ: SOPH) CEO Jurgi Camblong, PhD., to present at J.P. Morgan 2024 Healthcare Conference on January 11, 2024, in San Francisco.
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FAQ

What is the current stock price of Sophia Genetics Sa (SOPH)?

The current stock price of Sophia Genetics Sa (SOPH) is $2.76 as of April 4, 2025.

What is the market cap of Sophia Genetics Sa (SOPH)?

The market cap of Sophia Genetics Sa (SOPH) is approximately 182.8M.

What is SOPHiA GENETICS SA?

SOPHiA GENETICS SA is a cloud-native healthcare technology company that leverages AI, genomics, and advanced data analytics to facilitate data-driven medicine in clinical diagnostics and research.

What is the SOPHiA DDM™ Platform?

The SOPHiA DDM™ Platform is a comprehensive, cloud-based tool designed to analyze complex genomic and multimodal data, transforming it into actionable insights for clinical and research applications.

How does SOPHiA GENETICS support clinical diagnostics?

The company integrates advanced machine learning algorithms and bioinformatics to improve accuracy, reduce turnaround times, and lower costs in clinical diagnostics, particularly in precision oncology and rare disorders.

What role does artificial intelligence play in their technology?

AI is central to the platform’s functionality, enhancing data analysis capabilities, ensuring nearly 100% reproducibility, and enabling real-time insights from complex genomic data.

How does SOPHiA GENETICS ensure data security and privacy?

Employing high medical standards and rigorous quality assurance protocols, the company ensures patient data is securely stored and managed, meeting industry and regulatory guidelines for genomic privacy.

Who are the typical users of SOPHiA GENETICS' solutions?

Their solutions are employed by clinical laboratories, hospitals, research institutions, and biopharma companies seeking to improve diagnostic processes and advance precision medicine.

How is SOPHiA GENETICS positioned within the competitive landscape?

The company differentiates itself through its decentralized, cloud-native platform, Swiss precision, and a robust global network of clinical partners, which together enhance diagnostic accuracy and operational efficiency.

What clinical applications does the platform support?

The platform supports a range of applications, from routine genomic analyses to advanced oncology diagnostics such as liquid biopsy tests and solid tumor profiling, facilitating personalized treatment strategies.
Sophia Genetics Sa

Nasdaq:SOPH

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182.78M
62.47M
6.53%
54.32%
0.09%
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