Sanofi American Depositary Shares (Each representing one-half of one ordinary share) - SNY STOCK NEWS

On April 7, 2021, Sanofi announced the creation of Sanofi Global Health, a new nonprofit unit aimed at enhancing access to essential medicines in 40 lower-income countries. The initiative will provide 30 medicines across various therapeutic areas, alongside support for healthcare professionals. Additionally, Sanofi plans to donate 100,000 vials of treatments annually for rare diseases. The company also committed to reducing greenhouse gas emissions by 55% by 2030 and implementing zero plastic packaging for vaccines by 2027, while promoting diversity within its workforce.

The FDA has approved Sarclisa® (isatuximab-irfc) in combination with carfilzomib and dexamethasone for adult patients with relapsed or refractory multiple myeloma (RRMM) after one to three prior treatments. The approval is based on the Phase 3 IKEMA study, which demonstrated a 45% reduction in disease progression or death risk. Sarclisa now has two FDA-approved combinations for RRMM. Despite challenges in treating relapsed MM, the approval positions Sarclisa as a potential standard of care, enhancing its market potential.

Biond Biologics has signed an exclusive worldwide license agreement with Sanofi (SNY) for the development of BND-22, a humanized IgG4 antibody aimed at treating solid tumors. Biond will receive a $125 million upfront payment and potentially over $1 billion in milestones and royalties. BND-22 targets the inhibitory ILT2 receptor and has shown promising preclinical results by activating immune responses against tumors. The first-in-human phase 1a study is set to start by mid-2021, with Sanofi overseeing later clinical development.

Sanofi and the Parkinson's Foundation are collaborating to enhance genetic testing and counseling for Parkinson's disease patients in the U.S. Over two years, Sanofi will invest $1 million in the PD GENEration: Mapping the Future of Parkinson's Disease initiative. The study aims to improve understanding of genetic mutations related to Parkinson's, facilitating patient access to clinical trials. Initial results show a higher prevalence of genetic links to the disease, with plans to enroll 15,000 participants.

Sanofi Genzyme announced the presentation of new data from its neurology portfolio at MSVirtual2020, taking place from September 11-13, 2020. The event will showcase findings related to tolebrutinib (SAR442168), a selective BTK inhibitor aiming to address neuroinflammation in multiple sclerosis (MS). Key presentations will focus on the efficacy and safety of AUBAGIO® and LEMTRADA®, emphasizing their positive clinical profiles. Notable presentations include the effects of teriflunomide on pediatric MS patients and the long-term safety of alemtuzumab.

Sanofi reported its Q2 2020 results with net sales of €8,207 million, down 4.9% year-over-year. Specialty Care sales grew by 17.4%, primarily fueled by Dupixent®, which saw a 70% increase to €858 million. However, COVID-19 impacted sales in Vaccines and General Medicines, with declines of 6.8% and 12.7%, respectively. Business net income rose 3.6% to €1,601 million, while business EPS increased to €1.28. Sanofi revised its full-year 2020 business EPS guidance up to 6%-7%. Key regulatory advancements include Dupixent® approvals in China and for children in the U.S.

Sanofi and The University of Texas MD Anderson Cancer Center announced a five-year strategic collaboration on July 14, 2020, aimed at accelerating the development of cancer treatments. This alliance merges MD Anderson's clinical trial capabilities with Sanofi's investigational drug pipeline, focusing on biomarker-driven studies. The collaboration seeks to optimize patient selection and identify effective therapy combinations, thereby enhancing treatment outcomes for challenging cancers. Initial projects are expected to commence in summer 2020.

Kymera Therapeutics has formed a strategic collaboration with Sanofi (NASDAQ: SNY) to develop therapies targeting IRAK4 for immune-inflammatory diseases. The deal includes a $150 million upfront payment and potential milestones exceeding $2 billion. Kymera retains rights to its IRAK4 program in oncology and can participate in US development. IRAK4 is implicated in several inflammatory conditions, and preclinical studies show promising results. The partnership aims to leverage Sanofi's drug development expertise to enhance patient outcomes.

Sanofi and Sobi, alongside the World Federation of Hemophilia, have announced a further donation of up to 500 million IUs of factor therapy to the WFH Humanitarian Aid Program, completing their 2014 pledge to donate up to 1 billion IUs over ten years. Since 2015, the companies have donated over 450 million IUs, benefiting over 17,200 patients in 42 countries. This initiative aims to enhance treatment accessibility for hemophilia patients in developing regions, where more than 75% lack proper care.