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Sensei Biotherapeutics to Present New Preclinical Data at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting

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Sensei Biotherapeutics (Nasdaq: SNSE) has announced its participation in the SITC 37th Annual Meeting in Boston from November 8-12, 2022. The company will present two posters highlighting their advancements in immuno-oncology. The first presentation will focus on novel T-cell receptors related to the VSIG4 macrophage receptor, while the second will discuss SNS-101, an antibody that enhances anti-PD-1 sensitivity in tumors. These advancements underscore Sensei's commitment to developing innovative cancer therapeutics using their TMAb and ImmunoPhage platforms.

Positive
  • Participation in SITC 37th Annual Meeting indicates active engagement in the immuno-oncology field.
  • Presentation of two posters showcases advancements in T-cell receptor research and antibody development.
Negative
  • None.

BOSTON, Oct. 05, 2022 (GLOBE NEWSWIRE) -- Sensei Biotherapeutics, Inc. (Nasdaq: SNSE), an immuno-oncology company focused on the discovery and development of next-generation therapeutics for cancer, today announced it will present two posters at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting, being held in Boston, MA from November 8 - 12, 2022.

Presentation Details:

Title: Functional characterization of the inhibitory activity and identification of novel T-cell receptors for the tumor-associated macrophage receptor VSIG4   
Presentation Type: Poster
Abstract Number: 485
Date and Time: Thursday, November 10, 2022 at 9:00 a.m. ET – 9:00 p.m. ET
Location: Boston Convention and Exhibition Center

Title: SNS-101, a highly pH-selective VISTA:PSGL-1 inhibitory antibody, potentiates anti-PD-1 sensitivity, expands memory T-cells and enhances tumor infiltration of CD8 T-cells  
Presentation Type: Poster
Abstract Number: 856
Date and Time: Friday, November 11, 2022 at 9:00 a.m. ET – 9:00 p.m. ET
Location: Boston Convention and Exhibition Center

About Sensei Biotherapeutics
Sensei Biotherapeutics (NASDAQ: SNSE) is an immuno-oncology company focused on the discovery and development of next generation therapeutics for cancer. Sensei has designed two unique approaches to develop highly selective therapeutics – its TMAb™ (Tumor Microenvironment Activated biologics) platform, which disables checkpoints and other immunosuppressive signals in the tumor microenvironment to unleash existing T cells against tumors, and the ImmunoPhage™ platform, which trains new T cells to recognize and kill malignant cells. Using its TMAb platform, the company is developing SNS-101, a fully human antibody designed to block the V-domain Ig suppressor of T cell activation (VISTA) checkpoint selectively only within the low pH tumor microenvironment, where VISTA acts as a suppressor of T cells by binding the receptor PSGL-1. The company is also using its platforms to develop other preclinical programs targeting multiple solid tumor indications. For more information, please visit www.senseibio.com, and follow the company on Twitter @SenseiBio and LinkedIn.

Cautionary Note Regarding Forward-Looking Statements
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements may be identified by words and phrases such as “believe”, “designed to,” “expect”, “may”, “plan”, “potential”, “will”, and similar expressions, and are based on Sensei’s current beliefs and expectations. These forward-looking statements include expectations regarding the development of Sensei’s product candidates and platforms; the potential safety profile of Sensei’s product candidates; and the potential benefits of Sensei’s product candidates. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements. Risks and uncertainties that may cause actual results to differ materially include uncertainties inherent in the development of therapeutic product candidates, such as the risk that any one or more of Sensei’s product candidates will not be successfully developed or commercialized; the risk of delay or cessation of any planned clinical trials of Sensei’s product candidates; the risk that prior results, such as signals of safety, activity or durability of effect, observed from preclinical studies, including the preclinical studies described in this press release, will not be replicated or will not continue in ongoing or future studies or clinical trials involving Sensei’s product candidates; the risk that Sensei’s product candidates or procedures in connection with the administration thereof will not have the safety or efficacy profile that we anticipate; risks associated with Sensei’s dependence on third-party suppliers and manufacturers, including sole source suppliers, over which we may not always have full control; risks regarding the accuracy of our estimates of expenses, capital requirements and needs for additional financing; and other risks and uncertainties that are described in Sensei’s Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) on March 15, 2022 and Sensei’s other Periodic Reports filed with the SEC. Any forward-looking statements speak only as of the date of this press release and are based on information available to Sensei as of the date of this release, and Sensei assumes no obligation to, and does not intend to, update any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Contact:
Michael Biega
Senior Director, Investor Relations
Sensei Biotherapeutics
mbiega@senseibio.com

Media Contact:
Chris Railey
Ten Bridge Communications
chris@tenbridgecommunications.com


FAQ

What is the focus of Sensei Biotherapeutics at the SITC 37th Annual Meeting?

Sensei Biotherapeutics will present two posters highlighting their research on T-cell receptors and the SNS-101 antibody that enhances anti-PD-1 sensitivity.

When will Sensei Biotherapeutics present at the SITC meeting?

The presentations are scheduled for November 10 and 11, 2022.

What is the significance of SNS-101 in cancer treatment?

SNS-101 is designed to block the VISTA checkpoint in the tumor microenvironment, potentially increasing the effectiveness of T-cell therapies.

How does Sensei Biotherapeutics' TMAb platform work?

The TMAb platform aims to disable immunosuppressive signals in tumors to activate T-cells against cancer.

Sensei Biotherapeutics, Inc.

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