Salarius Pharmaceuticals Announces Titles of Three Abstracts Accepted for Poster Presentations at American Society of Clinical Oncology 2021 Annual Meeting

Rhea-AI Summary

Salarius Pharmaceuticals (Nasdaq: SLRX) announced that all three of its abstracts detailing research on seclidemstat have been accepted for poster presentations at the 2021 ASCO Annual Meeting, scheduled for June 4-8, 2021. One of the abstracts will also be featured in a poster discussion session. The findings address clinical trials focusing on potential treatments for pediatric cancers and advanced solid tumors. Seclidemstat has received multiple designations from the FDA, including Fast Track and Orphan Drug Designation.

Positive

• All three abstracts on seclidemstat accepted for presentation at ASCO 2021.
• Seclidemstat has received Fast Track Designation, Orphan Drug Designation, and Rare Pediatric Disease Designation from the FDA.

Negative

• None.

HOUSTON, April 29, 2021 (GLOBE NEWSWIRE) -- Salarius Pharmaceuticals, Inc. (Nasdaq: SLRX), a clinical-stage biopharmaceutical company developing potential new medicines for patients with pediatric cancers, solid tumors, and other cancers, announced today the titles of the abstracts accepted for poster presentations during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting. Salarius submitted three abstracts detailing research regarding seclidemstat, all of which have been accepted for poster presentations, with one abstract also selected for a poster discussion session. ASCO will be held virtually from June 4-8, 2021.

The titles of the abstracts are currently available on ASCO’s 2021 Meeting Library with full abstracts, including the dates and times of presentations, scheduled for publication at 5 p.m. ET on May 19, 2021. The titles of the presentations are as follows:

Abstract #11514: Phase 1 trial of seclidemstat (SP-2577) in patients with relapsed/refractory Ewing sarcoma.
Session: Poster Discussion Session, Sarcoma

Abstract #TPS11577: Phase 1 expansion trial of the LSD1 inhibitor seclidemstat (SP-2577) with and without topotecan and cyclophosphamide (TC) in patients (pts) with relapsed or refractory Ewing sarcoma (ES) and select sarcomas.
Session: Poster Session, Sarcoma

Abstract #3073: Preliminary efficacy from an ongoing phase 1 dose escalation study of seclidemstat (SP-2577) in patients (pts) with advanced solid tumors (AST).
Session: Poster Session, Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

“We are pleased to have all three of our submitted abstracts highlighting clinical research involving seclidemstat accepted for poster presentations at the 2021 ASCO Annual Meeting,” stated David Arthur, President and CEO of Salarius Pharmaceuticals. “As previously noted, the full findings from the dose-escalation stage of the Phase 1/2 trial of seclidemstat in patients with relapsed and refractory Ewing sarcoma, including details on safety, dosing, and initial efficacy signals, will be reported at the conference. Moreover, we will report preliminary data from a second clinical trial in patients with advanced solid tumors, which include additional select sarcomas that share a similar biology to Ewing sarcoma, also referred to as Ewing-related or FET-translocated sarcomas.”    

This year, ASCO received and reviewed more than 5,400 abstracts for the 2021 ASCO Annual Meeting. Information about the 2021 ASCO Annual Meeting may be accessed via the following website: https://conferences.asco.org/am/registration.

About Salarius Pharmaceuticals

Salarius Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing cancer therapies for patients in need of new treatment options. Salarius’ lead candidate, seclidemstat, is being studied as a potential treatment for pediatric cancers, solid tumors and other cancers with limited treatment options. Seclidemstat is currently in a Phase 1/2 clinical trial for relapsed/refractory Ewing sarcoma and additional select sarcomas that share a similar biology to Ewing sarcoma, also referred to as Ewing-related or FET-translocated sarcomas. Seclidemstat has received Fast Track Designation, Orphan Drug Designation and Rare Pediatric Disease Designation for Ewing sarcoma from the U.S. Food and Drug Administration. Salarius is also developing seclidemstat for several cancers with high unmet medical need, with a second Phase 1/2 clinical study in advanced solid tumors, including prostate, breast, and ovarian cancers. Salarius has received financial support from the National Pediatric Cancer Foundation to advance the Ewing sarcoma clinical program and was also a recipient of a Product Development Award from the Cancer Prevention and Research Institute of Texas (CPRIT). For more information, please visit salariuspharma.com or follow Salarius on Twitter and LinkedIn.

Forward-Looking Statements 

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this press release are forward-looking statements. These forward-looking statements may be identified by terms such as “anticipate,” “potential,” “progress,” “design,” “estimate,” “continue,” “will,” “aim,” “can,” “believe,” “plan,” “allow,” “expect,” “intend,” “goal,” “provide,” “able to,” “position,” “project,” “developing,” and similar terms or expressions or the negative thereof. Examples of such statements include, but are not limited to, statements relating to the following: the company’s growth strategy; the value of seclidemstat as a potential treatment for Ewing sarcoma, Ewing-related sarcomas and other cancers; the status and anticipated progress and milestones of the company’s clinical trials in Advanced Solid Tumors and Ewing sarcoma; the expansion of the company’s clinical trials to include Ewing-related sarcomas; the company’s belief as to being well-capitalized through the completion of its clinical trials for seclidemstat and beyond; Salarius’ goal to maximize the potential of seclidemstat; and Salarius developing seclidemstat for several cancers with high unmet medical need. Salarius may not actually achieve the plans, carry out the intentions or meet the expectations or objectives disclosed in the forward-looking statements. You should not place undue reliance on these forward-looking statements. These statements are subject to risks and uncertainties which could cause actual results and performance to differ materially from those discussed in the forward-looking statements. These risks and uncertainties include, but are not limited to, the following: the sufficiency of the company’s capital resources; the ability of, and need for, the company to raise additional capital to meet the company’s business operational needs and to achieve its business objectives and strategy; the company’s ability to project future capital needs and cash utilization and timing and accuracy thereof; the ability of the company to access the remaining funding available under the CPRIT grant; future clinical trial results and impact of results on the company; that the results of studies and clinical trials may not be predictive of future clinical trial results; the sufficiency of Salarius’ intellectual property protection; risks related to the drug development and the regulatory approval process; the competitive landscape and other industry-related risks; market conditions and regulatory or contractual restrictions which may impact the ability of Salarius to raise additional capital; the possibility of unexpected expenses or other uses of Salarius’ cash resources; risks related to the COVID-19 outbreak; and other risks described in Salarius’ filings with the Securities and Exchange Commission, including those discussed in the company’s quarterly report on Form 10-Q for the quarter ended September 30, 2020 and in the company’s annual report on Form 10-K for the year ended December 31, 2020. The forward-looking statements contained in this press release speak only as of the date of this press release and are based on management’s assumptions and estimates as of such date. Salarius disclaims any intent or obligation to update these forward- looking statements to reflect events or circumstances that exist after the date on which they were made.

Contact:
Tiberend Strategic Advisors, Inc.
Maureen McEnroe, CFA/Miriam Miller (investors)
(212) 375-2664 / 2694
mmcenroe@tiberend.com
mmiller@tiberend.com

Johanna Bennett (media)
(212) 375-2686 
jbennett@tiberend.com

FAQ

What presentations will Salarius Pharmaceuticals make at ASCO 2021?

Salarius will present three abstracts on seclidemstat at ASCO 2021, including one in a poster discussion session.

When is the ASCO Annual Meeting 2021?

The ASCO Annual Meeting 2021 is scheduled for June 4-8, 2021.

What is seclidemstat being studied for?

Seclidemstat is being studied as a potential treatment for pediatric cancers and advanced solid tumors.

What designations has seclidemstat received from the FDA?

Seclidemstat has received Fast Track Designation, Orphan Drug Designation, and Rare Pediatric Disease Designation.