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Salarius Pharmaceuticals Inc - SLRX STOCK NEWS

Welcome to our dedicated page for Salarius Pharmaceuticals news (Ticker: SLRX), a resource for investors and traders seeking the latest updates and insights on Salarius Pharmaceuticals stock.

Company Overview

Salarius Pharmaceuticals Inc (symbol: SLRX) is a clinical-stage biopharmaceutical company focused on developing novel oncology treatments. With a primary emphasis on targeted therapeutic strategies, the company leverages advanced science to address critical gene dysregulation in cancer cells. Utilizing industry-specific approaches such as protein inhibitors and protein degradation, Salarius is dedicated to designing treatments for patients with high unmet medical needs.

Core Therapeutic Approaches

The company concentrates on two main drug classes: targeted protein inhibitors and targeted protein degraders. Its product portfolio is constructed around two main candidates that exemplify these approaches. The strategic use of small molecules to modulate protein function and induce degradation represents a significant shift in conventional oncology therapies, aiming to interfere with specific molecular pathways in cancer.

Pipeline and Research Focus

Salarius Pharmaceuticals is actively engaged in clinical development aimed at treating cancers with limited treatment options. Its lead candidate, studied through investigator-initiated clinical trials, seeks to provide a new treatment avenue for hematologic malignancies, while its second candidate offers an innovative oral small molecule approach. The company’s research emphasizes a deep understanding of gene dysregulation, bringing forward detailed insights into molecular biology and therapeutic mechanisms. Precision oncology and targeted treatment strategies are central to its developmental focus, ensuring that each drug candidate addresses specific cellular anomalies in cancer.

Competitive Landscape and Market Position

Within the competitive realm of oncology therapeutics, Salarius distinguishes itself through a combination of innovative drug design and strategic collaborations. By focussing on precise molecular targets and innovative mechanisms such as targeted protein degradation, the company creates an opportunity to deliver treatments that may benefit patients with few alternatives. Its position in the market is underpinned by rigorous clinical research and clear scientific rationales, reinforcing its role within a specialized segment of biotechnology.

Strategic Collaborations and Business Model

The company’s recent strategic arrangements, including its merger-related activities with Decoy Therapeutics, highlight its commitment to integrating complementary technologies. By combining expertise in peptide conjugate therapeutics with its established focus on small molecule candidates, Salarius is building an innovative development framework. This collaboration is structured to leverage advanced computational design, machine learning, and rapid synthesis techniques, thereby enriching its portfolio with both established and next-generation therapeutic candidates.

Key Scientific Innovations

The scientific foundation of Salarius Pharmaceuticals is rooted in its rigorous exploration of gene dysregulation in cancer. Its drug candidates are designed with a deep understanding of molecular pathways, utilizing advanced small molecule techniques to inhibit or degrade specific target proteins. This dual approach not only exemplifies the company’s commitment to precision medicine but also reflects a broader trend in oncology research where multi-faceted intervention strategies are increasingly recognized as essential to tackling complex diseases.

Conclusion

Salarius Pharmaceuticals Inc is a company built on robust scientific inquiry and a commitment to innovation in cancer treatment. Its strategic exploration of both protein inhibition and degradation provides a solid groundwork for addressing substantial unmet medical needs in oncology. By maintaining a focus on precision therapeutic approaches and leveraging strategic collaborations, the company continues to develop a diversified clinical-stage pipeline that underscores its expertise and authority in the biopharmaceutical field.

Rhea-AI Summary

Salarius Pharmaceuticals (Nasdaq: SLRX) has announced the commencement of an underwritten public offering of its common stock. The offering is subject to market conditions, and details regarding its size and terms remain undetermined. Ladenburg Thalmann & Co. Inc. is the sole book-running manager for this offering. The company has a registered shelf statement with the SEC, allowing for the sale of shares. Salarius focuses on developing new cancer therapies, particularly for pediatric and other challenging cancers, with its lead candidate currently undergoing clinical trials.

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Salarius Pharmaceuticals (Nasdaq: SLRX) has initiated the expansion stage of its Phase 1/2 clinical trial for seclidemstat, targeting relapsed and refractory Ewing sarcoma patients. This phase includes two arms: combining seclidemstat with topotecan and cyclophosphamide for Ewing sarcoma, and using it as a single-agent therapy for Ewing-related sarcomas. Preliminary results show extended time to progression, with data readouts expected by the end of 2021 into 2022. The company aims to enhance treatment options for patients with limited alternatives.

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Salarius Pharmaceuticals (Nasdaq: SLRX) announced that CEO David Arthur will present at the Diamond Equity Research Emerging Growth Invitational Conference on February 24, 2021. The presentation will cover Salarius’ business overview, recent achievements, and upcoming clinical milestones for seclidemstat, a reversible LSD1 inhibitor currently in Phase 1/2 trials for Ewing sarcoma and advanced solid tumors. Attendees can participate in a Q&A session. A recording will be available post-event on the company’s investor page.

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Salarius Pharmaceuticals has established the recommended Phase 2 dose (RP2D) for its seclidemstat in a Phase 1/2 trial focused on relapsed/refractory Ewing sarcoma. Data from the trial showcased a manageable safety profile and preliminary signs of drug activity, particularly in Ewing-related sarcoma patients. Encouraging results indicated over 75% tumor shrinkage in a refractory patient. The trial plans to expand to treat more patients and present full findings at a medical conference. Further data readouts are expected by the end of this year and early next year.

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Salarius Pharmaceuticals announced its participation in the BIO CEO & Investor Digital Conference from February 16 to February 18, 2021. The company's management will engage in one-on-one virtual meetings with investors to discuss business developments and milestones related to seclidemstat, a reversible LSD1 inhibitor in clinical trials for Ewing sarcoma and advanced solid tumors. Salarius has received multiple FDA designations for seclidemstat and financial backing for its clinical programs, emphasizing its commitment to innovative cancer therapies.

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Salarius Pharmaceuticals (Nasdaq: SLRX) announced it has regained compliance with Nasdaq's minimum bid price requirement, ensuring its continued listing on the Nasdaq Capital Market. The company focuses on developing innovative cancer therapies, particularly its lead candidate, seclidemstat, which is in clinical trials for pediatric cancers and advanced solid tumors. Salarius has received multiple designations from the FDA for seclidemstat and financial support from the National Pediatric Cancer Foundation and CPRIT to further its clinical programs.

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Salarius Pharmaceuticals (Nasdaq: SLRX) announced that Dr. Daniela Y. Santiesteban will join the panel on Targeted Cancer Therapeutics at Noble Capital Markets’ 17th Annual Small & Microcap Investor Conference, taking place January 19-21, 2021, virtually. The discussion will focus on the status and future of targeted cancer therapies. Salarius is advancing its lead candidate, seclidemstat, a reversible LSD1 inhibitor, currently undergoing clinical trials for Ewing sarcoma and advanced solid tumors. The company aims to establish maximum tolerated dose in its ongoing trials.

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Salarius Pharmaceuticals (Nasdaq: SLRX) announced a $0.9 million payment from the Cancer Prevention and Research Institute of Texas, part of a $1.7 million grant for its lead drug candidate, seclidemstat. This funding supports two clinical trials targeting Ewing sarcoma and advanced solid tumors. With a total of $4.8 million in remaining funds, Salarius is positioned to advance its clinical programs. The company has secured additional funding of $3.6 million from prior financing efforts, allowing it to progress through critical development milestones in 2021.

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Salarius Pharmaceuticals is set to participate in the Biotech Showcase Digital and BIO @ JPM from January 11-15, 2021. This virtual participation coincides with the 39th Annual Healthcare Conference 2021. Salarius aims to discuss its clinical programs for seclidemstat, a potential treatment for Ewing sarcoma and other cancers. Key milestones include establishing maximum tolerated doses and advancing into the dose-expansion phase of trials. Salarius has received FDA designations for its lead candidate, focusing on pediatric and solid tumors.

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Salarius Pharmaceuticals (Nasdaq: SLRX) announced agreements with institutional investors to exercise outstanding warrants, raising approximately $3.5 million by issuing 3,964,065 shares. This follows their public offering in February 2020. The exercised warrants' price was reduced from $1.15 to $0.90 to encourage immediate cash exercise. New warrants will allow the purchase of additional shares at $1.182, exercisable in six months. The funds will support the development of seclidemstat, focusing on pediatric and solid tumors, with key milestones expected in early 2021.

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FAQ

What is the current stock price of Salarius Pharmaceuticals (SLRX)?

The current stock price of Salarius Pharmaceuticals (SLRX) is $0.7265 as of April 2, 2025.

What is the market cap of Salarius Pharmaceuticals (SLRX)?

The market cap of Salarius Pharmaceuticals (SLRX) is approximately 1.2M.

What is the primary focus of Salarius Pharmaceuticals Inc?

Salarius Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing targeted oncology treatments that address critical gene dysregulation in cancer.

Which therapeutic approaches does the company utilize?

The company employs targeted protein inhibition and protein degradation strategies, leveraging small molecule therapies to modulate or degrade disease-causing proteins in cancer cells.

What are the main drug candidates in their pipeline?

Salarius is developing therapies that include a lead candidate currently being explored for hematologic cancers and an oral small molecule protein degrader under IND-stage evaluation.

How does Salarius differentiate itself in the competitive oncology market?

The company differentiates itself through a dual approach that combines advanced molecular targeting with innovative therapeutic modalities, positioning it uniquely in addressing high unmet needs in cancer treatment.

What role does targeted gene dysregulation play in their treatment strategies?

Targeting gene dysregulation is central to their approach, enabling the design of therapies that interfere precisely with abnormal protein functions, thereby potentially improving treatment outcomes in oncology.

How is the company integrating innovative technologies into its drug development?

Salarius is incorporating advanced computational design, machine learning, and rapid synthesis techniques to enhance its drug discovery process and develop both small molecule and peptide-based therapeutics.

What can be understood about their strategic collaboration with Decoy Therapeutics?

The collaboration with Decoy Therapeutics reflects a strategic effort to merge complementary technologies, particularly peptide conjugate therapeutics, with Salarius' existing expertise, thereby creating a broader and more innovative research platform.

How do the company's initiatives contribute to addressing unmet medical needs in oncology?

By focusing on precise molecular targets and leveraging innovative drug modalities, Salarius aims to create effective treatments for patients with limited options, thus addressing critical gaps in current oncology care.
Salarius Pharmaceuticals Inc

Nasdaq:SLRX

SLRX Rankings

SLRX Stock Data

1.21M
1.71M
2.1%
4.8%
5.41%
Biotechnology
Pharmaceutical Preparations
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United States
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