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Skye Bioscience, Inc. - SKYE STOCK NEWS

Welcome to our dedicated page for Skye Bioscience news (Ticker: SKYE), a resource for investors and traders seeking the latest updates and insights on Skye Bioscience stock.

Skye Bioscience, Inc. (Nasdaq: SKYE) is a cutting-edge, clinical-stage biopharmaceutical company based in San Diego, California. Focused on the development of innovative therapies, Skye leverages the endocannabinoid system to address diseases characterized by metabolic, inflammatory, and fibrotic processes.

The company's prominent clinical candidates include nimacimab and SBI-100 Ophthalmic Emulsion (SBI-100 OE). Nimacimab is a groundbreaking humanized monoclonal antibody that functions as a negative allosteric modulator of the cannabinoid 1 receptor (CB1). By targeting CB1 in peripheral tissues, nimacimab aims to treat diseases like obesity, chronic kidney disease, and metabolic dysfunction-associated steatohepatitis (MASH) without the central nervous system (CNS) side effects that plagued earlier CB1 inhibitors. Currently, Skye is gearing up for a Phase 2 clinical trial of nimacimab in patients with obesity and chronic kidney disease, expected to begin in mid-2024.

Meanwhile, SBI-100 OE is under investigation for its potential to lower intraocular pressure in patients suffering from glaucoma and ocular hypertension. Although the Phase 2a trial did not meet its primary endpoint for reducing intraocular pressure, the drug demonstrated a favorable safety profile, paving the way for further research and development.

Recent news highlights Skye's strategic focus and financial stability. As of June 2024, the company announced the discontinuation of clinical development for SBI-100 OE, allowing Skye to redirect resources fully towards its metabolic program, extending its operational runway into 2027. Backed by leading life science venture investors, including Perceptive Advisors and 5AM Ventures, Skye successfully raised $90.25 million through two private placements in the first quarter of 2024, ensuring robust financial resources to support its ambitious clinical development plans.

For more information, please visit the company's website at www.skyebioscience.com.

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Skye Bioscience (OTCQB: SKYE), a biopharmaceutical firm, announced its participation in the virtual H.C. Wainwright BIOCONNECT Conference from January 10-13, 2022. CEO Punit Dhillon will present an on-demand overview on January 10 at 7 AM ET, accessible via a webcast. Virtual one-on-one meetings will also be available for institutional investors. Skye's lead program is focused on developing cannabinoid-derived treatments for glaucoma.

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Skye Bioscience has appointed Keith W. Ward, PhD to its board of directors and promoted Tu Diep, MSc to Chief Development Officer. This leadership change aims to enhance the company's direction in developing cannabinoid-based therapies targeting significant unmet medical needs, particularly in treating glaucoma. Dr. Ward brings over 25 years of industry experience, while Mr. Diep, previously Senior VP of Development, has over 15 years in drug development. The company emphasizes its focus on advancing therapies in a challenging therapeutic landscape.

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Skye Bioscience (OTCQB: SKYE) announced that researchers from the University of Mississippi presented two studies at the AAPS PharmSci 360 meeting. The studies focused on the effects of THCVHS, a synthetic cannabinoid, on lowering intraocular pressure (IOP) in glaucoma treatment. Findings revealed that THC-VHS nanoemulsion formulations showed better IOP reduction compared to standard treatments. The company is advancing its clinical strategy, with human trials expected to start in Q2-22, focusing on safety and efficacy for glaucoma treatment.

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Skye Bioscience (OTCQB: SKYE) has signed an exclusive research agreement with Emerald Health Biotechnology Espana SLU to develop cannabinoid-derived molecules for therapeutic purposes. This agreement, dubbed the Cannabinoid Pharmaceutical Innovation Program (CPIP), aims to enhance signaling pathways in the endocannabinoid system. Skye will finance the projects and retain rights to all resulting data and intellectual property. The initiative aims to create a portfolio of proprietary products that focus on treating diseases with significant unmet needs, particularly in ophthalmology.

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Skye Bioscience (OTCQB: SKYE) has appointed Rhea Williams, MPH, as Head of Regulatory Affairs & Quality Assurance and Varun Khurana, PhD, as Senior Director of Research & Development. Williams has over 25 years of experience in drug development across multiple disease areas. Khurana brings over seven years of expertise in drug formulation and development, having previously worked at GlaxoSmithKline. The company aims to initiate its first-in-human trial for glaucoma, signaling an important phase in its growth strategy.

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Skye Bioscience, Inc. (OTCQB: SKYE) has appointed Kaitlyn Arsenault, CPA, as its new Chief Financial Officer. With over 14 years of experience in financial reporting and operations, Arsenault previously served as an independent consultant for emerging companies, including Skye. CEO Punit Dhillon highlighted her expertise in financial controls and reporting as crucial for the company's clinical development and growth objectives. Arsenault expressed commitment to advancing Skye's financial priorities and stakeholder commitments.

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Skye Bioscience (SKYE) has successfully closed a registered direct offering, selling 77,777,779 shares of common stock and warrants at an effective price of $0.09 per share, grossing approximately $7 million. The proceeds will support general corporate purposes, including working capital and potential acquisitions. The warrants are exercisable immediately and expire in five years. CEO Punit Dhillon emphasizes that this financing positions the company to advance its drug candidate for glaucoma and enhance its pharmaceutical cannabinoid R&D initiatives, aiming to build shareholder value.

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Skye Bioscience (OTCQB: SKYE) has announced a registered direct offering of 77,777,779 shares of its common stock and warrants, priced at $0.09 per share, yielding expected gross proceeds of approximately $7.0 million. The offering is set to close around September 29, 2021. Proceeds will be used for general corporate purposes, including working capital and potential acquisitions. The offering is conducted under an effective SEC registration statement. H.C. Wainwright & Co. serves as the exclusive placement agent.

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Skye Bioscience (OTCQB: SKYE) announced that its research partner, the University of Mississippi, will present new preclinical data on its prodrug, THCVHS, at the AAPS PharmSci 360 conference from October 17-20, 2021. The data demonstrates the effectiveness of THCVHS nanoemulsion formulations in lowering intraocular pressure in dutch belted rabbits, especially when used with netarsudil, a rho-kinase inhibitor. Key presentations will occur on October 18 and 19, showcasing the potential of THCVHS in addressing glaucoma, a leading cause of irreversible blindness.

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Skye Bioscience, Inc. (OTCQB: SKYE) announced a virtual investor presentation scheduled for October 12, 2021, at 1 p.m. ET, focusing on the company's strategic direction for 2022 and updates on its glaucoma treatment program. The event will feature Skye's management team and advisory board members, followed by a Q&A session. Investors can submit questions by September 28, 2021, and must register in advance to attend. Skye is dedicated to developing cannabinoid-derived therapies for significant health issues, with its lead program targeting glaucoma.

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FAQ

What is the current stock price of Skye Bioscience (SKYE)?

The current stock price of Skye Bioscience (SKYE) is $2.7 as of December 20, 2024.

What is the market cap of Skye Bioscience (SKYE)?

The market cap of Skye Bioscience (SKYE) is approximately 88.1M.

What does Skye Bioscience, Inc. specialize in?

Skye Bioscience specializes in developing novel therapies targeting the endocannabinoid system to treat diseases with metabolic, inflammatory, and fibrotic processes.

What are the main clinical candidates for Skye Bioscience?

The main clinical candidates are nimacimab, a monoclonal antibody targeting peripheral CB1 receptors, and SBI-100 Ophthalmic Emulsion, currently under investigation for glaucoma and ocular hypertension.

What recent financial developments has Skye Bioscience announced?

In the first quarter of 2024, Skye raised $90.25 million through two private placements, ensuring financial stability for its ongoing and upcoming clinical trials.

What is the status of Skye Bioscience's SBI-100 Ophthalmic Emulsion?

The Phase 2a trial did not meet its primary endpoint for lowering intraocular pressure, leading Skye to discontinue further development of SBI-100 OE.

When is the Phase 2 clinical trial for nimacimab expected to start?

The Phase 2 clinical trial for nimacimab is expected to begin dosing in mid-2024.

What diseases does nimacimab target?

Nimacimab targets diseases such as obesity, chronic kidney disease, and metabolic dysfunction-associated steatohepatitis (MASH) by inhibiting peripheral CB1 receptors.

Who are Skye Bioscience's key investors?

Key investors include Perceptive Advisors, 5AM Ventures, Velan Capital, and Schonfeld Strategic Advisors, among others.

What is Skye Bioscience's strategy for clinical development?

Skye focuses on leveraging biologic targets with substantial human proof of mechanism to develop first-in-class therapeutics with significant clinical and commercial differentiation.

How can I contact Skye Bioscience for more information?

You can contact Skye Bioscience's Investor Relations via email at ir@skyebioscience.com or phone at (858) 410-0266.

What is the focus of Skye Bioscience's current research and development efforts?

Skye is currently focusing all its efforts on broadening its metabolic clinical pipeline, following the discontinuation of its ophthalmology program.

Skye Bioscience, Inc.

OTC:SKYE

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SKYE Stock Data

88.13M
29.94M
1.32%
86.09%
6.57%
Biotechnology
Pharmaceutical Preparations
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United States of America
SAN DIEGO